HTLV1 Target gene Detail Information

> SPIRE2 Gene Search Result


Gene Information
Gene Name SPIRE2
Gene ID 84501
Gene Full Name spire type actin nucleation factor 2
Gene Alias Spir-2
Transcripts ENSG00000204991
Virus HTLV1
Gene Type protein-coding
HPA Location Info Nucleoplasm;Vesicles, Intermediate filaments;
Membrane Info Predicted intracellular proteins
Uniport_ID Q8WWL2
HGNC ID HGNC:30623
OMIM ID 609217
Summary Predicted to enable microtubule binding activity. Involved in establishment of meiotic spindle localization; formin-nucleated actin cable assembly; and positive regulation of double-strand break repair. Predicted to be located in cleavage furrow. Predicted to be active in cell cortex and cytoplasmic vesicle membrane. [provided by Alliance of Genome Resources, Apr 2025]
Target gene [SPIRE2] related to VISs

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section


DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
6003000 chr16 125 32 34 191 View
6005352 chr16 87 1 1 89 View
6023203 chr16 2 2 0 4 View

Target gene [SPIRE2] related to Omics data
Data ID Experiment type Sample number Platform
C
  GSE94732 		Chip-seq 24 Illumina NextSeq 500 (Homo sapiens);illumina Genome Analyzer IIx (Homo sapiens)
GSE168557 Expression array 6 Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Feature Number version)
GSE10789 Expression array 6 NCI/ATC Hs-OperonV3
GSE189602 Methylation profiling (Array) 4 Infinium MethylationEPIC
GSE136189 Methylation profiling (Array) 40 Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482);Illumina Infinium HumanMethylation850 BeadChip


When the gene can detect a peak in the dataset, a peak plot will be displayed.


> Dataset: GSE94732 - SPIRE2 peak across samples

Peak Plot