Gene Name	TMEM63C
Gene ID	57156
Gene Full Name	transmembrane protein 63C
Gene Alias	C14orf171|CSC1|SPG87|hsCSC1
Transcripts	ENSG00000165548
Virus	HTLV1
Gene Type	protein-coding
HPA Location Info	Centrosome;
Membrane Info	Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters
Uniport_ID	Q9P1W3
HGNC ID	HGNC:23787
OMIM ID	619953
Summary	Enables calcium-activated cation channel activity. Involved in monoatomic cation transport. Predicted to be located in endoplasmic reticulum membrane. Predicted to be active in plasma membrane. Implicated in hereditary spastic paraplegia 87. Biomarker of focal segmental glomerulosclerosis. [provided by Alliance of Genome Resources, Apr 2025]

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
6009593	chr14	32	4	0	36	View
6014512	chr14	2	13	1	16	View
6014601	chr14	13	3	0	16	View
6015137	chr14	14	1	0	15	View
6023968	chr14	4	0	0	4	View

Data ID	Experiment type	Sample number	Platform
C   GSE94732	Chip-seq	24	Illumina NextSeq 500 (Homo sapiens);illumina Genome Analyzer IIx (Homo sapiens)
GSE168557	Expression array	6	Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Feature Number version)
GSE224047	RNA-seq	10	Illumina NextSeq 500 (Homo sapiens)
GSE189602	Methylation profiling (Array)	4	Infinium MethylationEPIC
GSE136189	Methylation profiling (Array)	40	Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482);Illumina Infinium HumanMethylation850 BeadChip

• Genome binding/occupancy profiling

When the gene can detect a peak in the dataset, a peak plot will be displayed.

> Dataset: GSE94732 - TMEM63C peak across samples

Peak Plot