Gene Name	UFD1
Gene ID	7353
Gene Full Name	ubiquitin recognition factor in ER associated degradation 1
Gene Alias	UFD1L
Transcripts	ENSG00000070010
Virus	HTLV1
Gene Type	protein-coding
HPA Location Info	Nucleoplasm, Cytosol;Nucleoli;
Membrane Info	Predicted intracellular proteins, Transporters
Uniport_ID	Q92890
HGNC ID	HGNC:12520
OMIM ID	601754
Summary	The protein encoded by this gene forms a complex with two other proteins, nuclear protein localization-4 and valosin-containing protein, and this complex is necessary for the degradation of ubiquitinated proteins. In addition, this complex controls the disassembly of the mitotic spindle and the formation of a closed nuclear envelope after mitosis. Mutations in this gene have been associated with Catch 22 syndrome as well as cardiac and craniofacial defects. Alternative splicing results in multiple transcript variants encoding different isoforms. A related pseudogene has been identified on chromosome 18. [provided by RefSeq, Jun 2009]

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
6020387	chr22	6	1	0	7	View

Data ID	Experiment type	Sample number	Platform
GSE52244	Expression array	15	[HuEx-1_0-st] Affymetrix Human Exon 1.0 ST Array [probe set (exon) version]
GSE224047	RNA-seq	10	Illumina NextSeq 500 (Homo sapiens)
C   GSE94732	Chip-seq	24	Illumina NextSeq 500 (Homo sapiens);illumina Genome Analyzer IIx (Homo sapiens)

• Genome binding/occupancy profiling

When the gene can detect a peak in the dataset, a peak plot will be displayed.

> Dataset: GSE94732 - UFD1 peak across samples

Peak Plot