HBV Target gene Detail Information

> UNC13B Gene Search Result


Gene Information
Gene Name UNC13B
Gene ID 10497
Gene Full Name unc-13 homolog B
Gene Alias MUNC13|UNC13|Unc13h2|munc13-2
Transcripts ENSG00000198722
Virus HBV
Gene Type protein-coding
HPA Location Info Vesicles;Nucleoplasm, Golgi apparatus, Intermediate filaments;
Membrane Info Predicted intracellular proteins
Uniport_ID O14795
HGNC ID HGNC:12566
OMIM ID 605836
Summary This gene is expressed in the kidney cortical epithelial cells and is upregulated by hyperglycemia. The encoded protein shares a high level of similarity to the rat homolog, and contains 3 C2 domains and a diacylglycerol-binding C1 domain. Hyperglycemia increases the levels of diacylglycerol, which has been shown to induce apoptosis in cells transfected with this gene and thus contribute to the renal cell complications of hyperglycemia. Studies in other species also indicate a role for this protein in the priming step of synaptic vesicle exocytosis. [provided by RefSeq, Jul 2008]
Target gene [UNC13B] related to VISs

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section


DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1006900 chr9 31 0 1 32 View
1008228 chr9 19 3 0 22 View
1008714 chr9 4 12 3 19 View
1008907 chr9 4 11 3 18 View
1013134 chr9 4 1 0 5 View
1021219 chr9 4 11 3 18 View
1021220 chr9 31 0 1 32 View
1021221 chr9 4 12 3 19 View
1021222 chr9 4 1 0 5 View
1043447 chr9 50 9 13 72 View
1043448 chr9 31 5 0 36 View
1043449 chr9 4 3 0 7 View
1043450 chr9 4 14 13 31 View

Target gene [UNC13B] related to Omics data
Data ID Experiment type Sample number Platform
GSE236281 RNA-seq 12 Illumina MiSeq (Homo sapiens)
C
  GSE35465 		Chip-seq;RNA-seq 6 Illumina HiSeq 2000 (Homo sapiens)
C
  GSE68402 		Chip-seq 26 Illumina MiSeq (Homo sapiens);Illumina HiSeq 2500 (Homo sapiens)
TCGA_LIHC_HBV DNA methylation sequencing;RNA-seq 97 TCGA
C
  GSE270130 		Chip-seq 27 Illumina NovaSeq 6000 (Homo sapiens)
GSE224901 RNA-seq 21 Illumina NovaSeq 6000 (Homo sapiens)
C
  GSE100400 		Chip-seq;RNA-seq;4C_cccDNA 31 Illumina NextSeq 500 (Homo sapiens);Illumina NextSeq 500 (Mus musculus)
GSE173897 RNA-seq 95 Illumina HiSeq 4000 (Homo sapiens)
GSE262515 RNA-seq 21 Illumina HiSeq 2500 (Homo sapiens);Illumina HiSeq 2500 (Mus musculus)
GSE110345 RNA-seq 4 Illumina HiSeq 2500 (Homo sapiens)
C
  GSE131257 		ATAC-seq;RNA-seq 19 Illumina HiSeq 2500 (Homo sapiens)
GSE94660 RNA-seq 42 Illumina HiSeq 2500 (Homo sapiens)


When the gene can detect a peak in the dataset, a peak plot will be displayed.


> Dataset: GSE35465 - UNC13B peak across samples

Peak Plot

> Dataset: GSE68402 - UNC13B peak across samples

Peak Plot

> Dataset: GSE270130 - UNC13B peak across samples

Peak Plot

> Dataset: GSE100400 - UNC13B peak across samples

Peak Plot

> Dataset: GSE131257 - UNC13B peak across samples

Peak Plot