Gene Name	VIM
Gene ID	7431
Gene Full Name	vimentin
Gene Alias	-
Transcripts	ENSG00000026025
Virus	JEV
Gene Type	protein-coding
HPA Location Info	Intermediate filaments;
Membrane Info	Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins
Uniport_ID	P08670
HGNC ID	HGNC:12692
OMIM ID	193060
Summary	This gene encodes a type III intermediate filament protein. Intermediate filaments, along with microtubules and actin microfilaments, make up the cytoskeleton. The encoded protein is responsible for maintaining cell shape and integrity of the cytoplasm, and stabilizing cytoskeletal interactions. This protein is involved in neuritogenesis and cholesterol transport and functions as an organizer of a number of other critical proteins involved in cell attachment, migration, and signaling. Bacterial and viral pathogens have been shown to attach to this protein on the host cell surface. Mutations in this gene are associated with congenital cataracts in human patients. [provided by RefSeq, Aug 2017]

Mutation Table: if previous studies reported that target gene was related to virus gene/region/protein, the information in this literature was listed in this section

ID	PMID	Mutation	Gene/Protein/Region	Encoding Gene/Protein	Disease	Description	Detail
1	21707907	E138K	E	envelope	Cell line	T	View

Data ID	Experiment type	Sample number	Platform
GSE221680	RNA-seq	6	Illumina HiSeq 2500 (Homo sapiens)