Gene Information
|
Gene Name
|
WDR77 |
|
Gene ID
|
79084
|
|
Gene Full Name
|
WD repeat domain 77 |
|
Gene Alias
|
HKMT1069|MEP-50|MEP50|Nbla10071|p44|p44/Mep50 |
|
Transcripts
|
ENSG00000116455
|
|
Virus
|
HEV |
|
Gene Type
|
protein-coding |
|
HPA Location Info
|
Nucleoplasm, Cytosol;Golgi apparatus;
|
|
Membrane Info
|
Predicted intracellular proteins |
|
Uniport_ID
|
Q9BQA1
|
|
HGNC ID
|
HGNC:29652
|
|
OMIM ID
|
611734 |
|
Summary
|
The protein encoded by this gene is an androgen receptor coactivator that forms a complex with protein arginine methyltransferase 5, which modifies specific arginines to dimethylarginines in several spliceosomal Sm proteins. The encoded protein may be involved in the early stages of prostate cancer, with most of the protein being nuclear-localized in benign cells but cytoplasmic in cancer cells. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2015] |
Target gene [WDR77] related to virus gene/protein/region
Mutation Table: if previous studies reported that target gene was related to virus gene/region/protein, the information in this literature was listed in this section
| ID |
PMID |
Mutation |
Gene/Protein/Region |
Encoding Gene/Protein |
Disease |
Description |
Detail |
| 1 |
37276230 |
R458K |
ORF1
|
ORF1
|
Cell line
|
I
T
|
View |
Target gene [WDR77] related to Omics data
| Data ID |
Experiment type |
Sample number |
Platform |
|
GSE262469
|
RNA-seq |
15 |
Illumina NovaSeq 6000 (Homo sapiens) |
|
GSE251924
|
RNA-seq |
6 |
Illumina NovaSeq 6000 (Homo sapiens) |
|
GSE274780
|
RNA-seq |
12 |
Illumina NextSeq 500 (Homo sapiens) |
|
|