HEV Target gene Detail Information

> WDR77 Gene Search Result


Gene Information
Gene Name WDR77
Gene ID 79084
Gene Full Name WD repeat domain 77
Gene Alias HKMT1069|MEP-50|MEP50|Nbla10071|p44|p44/Mep50
Transcripts ENSG00000116455
Virus HEV
Gene Type protein-coding
HPA Location Info Nucleoplasm, Cytosol;Golgi apparatus;
Membrane Info Predicted intracellular proteins
Uniport_ID Q9BQA1
HGNC ID HGNC:29652
OMIM ID 611734
Summary The protein encoded by this gene is an androgen receptor coactivator that forms a complex with protein arginine methyltransferase 5, which modifies specific arginines to dimethylarginines in several spliceosomal Sm proteins. The encoded protein may be involved in the early stages of prostate cancer, with most of the protein being nuclear-localized in benign cells but cytoplasmic in cancer cells. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2015]
Target gene [WDR77] related to virus gene/protein/region

Mutation Table: if previous studies reported that target gene was related to virus gene/region/protein, the information in this literature was listed in this section


ID PMID Mutation Gene/Protein/Region Encoding Gene/Protein Disease Description Detail
1 37276230 R458K
ORF1
ORF1
Cell line
I
T
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Target gene [WDR77] related to Omics data
Data ID Experiment type Sample number Platform
GSE262469 RNA-seq 15 Illumina NovaSeq 6000 (Homo sapiens)
GSE251924 RNA-seq 6 Illumina NovaSeq 6000 (Homo sapiens)
GSE274780 RNA-seq 12 Illumina NextSeq 500 (Homo sapiens)