HBV Target gene Detail Information

> YAP1 Gene Search Result


Gene Information
Gene Name YAP1
Gene ID 10413
Gene Full Name Yes1 associated transcriptional regulator
Gene Alias COB1|YAP|YAP-1|YAP2|YAP65|YKI
Transcripts ENSG00000137693
Virus HBV
Gene Type protein-coding
HPA Location Info Nucleoplasm;Nucleoli, Cytosol;
Membrane Info Disease related genes, Human disease related genes, Predicted intracellular proteins
Uniport_ID P46937
HGNC ID HGNC:16262
OMIM ID 606608
Summary This gene encodes a downstream nuclear effector of the Hippo signaling pathway which is involved in development, growth, repair, and homeostasis. This gene is known to play a role in the development and progression of multiple cancers as a transcriptional regulator of this signaling pathway and may function as a potential target for cancer treatment. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2013]
Target gene [YAP1] related to VISs

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section


DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1009400 chr11 15 1 0 16 View
1014224 chr11 0 4 0 4 View
1017323 chr11 1 0 0 1 View
1024450 chr11 7 1 0 8 View

Target gene [YAP1] related to Omics data
Data ID Experiment type Sample number Platform
GSE236281 RNA-seq 12 Illumina MiSeq (Homo sapiens)
C
  GSE35465
Chip-seq;RNA-seq 6 Illumina HiSeq 2000 (Homo sapiens)
GSE199850 scRNA-seq 1 HiSeq X Ten (Homo sapiens)
C
  GSE68402
Chip-seq 26 Illumina MiSeq (Homo sapiens);Illumina HiSeq 2500 (Homo sapiens)
TCGA_LIHC_HBV DNA methylation sequencing;RNA-seq 97 TCGA
C
  GSE270130
Chip-seq 27 Illumina NovaSeq 6000 (Homo sapiens)
GSE224901 RNA-seq 21 Illumina NovaSeq 6000 (Homo sapiens)
E
 
C
  GSE100400
Chip-seq;RNA-seq;4C_cccDNA 31 Illumina NextSeq 500 (Homo sapiens);Illumina NextSeq 500 (Mus musculus)
GSE173897 RNA-seq 95 Illumina HiSeq 4000 (Homo sapiens)
GSE262515 RNA-seq 21 Illumina HiSeq 2500 (Homo sapiens);Illumina HiSeq 2500 (Mus musculus)
GSE110345 RNA-seq 4 Illumina HiSeq 2500 (Homo sapiens)
C
  GSE131257
ATAC-seq;RNA-seq 19 Illumina HiSeq 2500 (Homo sapiens)
E
  GSE94660
RNA-seq 42 Illumina HiSeq 2500 (Homo sapiens)


When the query gene is differentially changed in the dataset, a volcano/bar plot will be displayed.


> Dataset: GSE100400 - YAP1 expression across samples

Volcano Plot


Bar Plot


> Dataset: GSE94660 - YAP1 expression across samples

Volcano Plot


Bar Plot