Gene Name	ZNF423
Gene ID	23090
Gene Full Name	zinc finger protein 423
Gene Alias	Ebfaz|JBTS19|NPHP14|OAZ|Roaz|ZFP423|Zfp104|hOAZ
Transcripts	ENSG00000102935
Virus	HBV
Gene Type	protein-coding
HPA Location Info	Nucleoplasm;
Membrane Info	Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors
Uniport_ID	Q2M1K9
HGNC ID	HGNC:16762
OMIM ID	604557
Summary	The protein encoded by this gene is a nuclear protein that belongs to the family of Kruppel-like C2H2 zinc finger proteins. It functions as a DNA-binding transcription factor by using distinct zinc fingers in different signaling pathways. Thus, it is thought that this gene may have multiple roles in signal transduction during development. Mutations in this gene are associated with nephronophthisis-14 and Joubert syndrome-19. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2012]

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1003934	chr16	59	37	4	100	View
1015201	chr16	2	0	0	2	View
1022117	chr16	2	0	0	2	View
1042191	chr16	3	0	0	3	View

Data ID	Experiment type	Sample number	Platform
GSE236281	RNA-seq	12	Illumina MiSeq (Homo sapiens)
C   GSE35465	Chip-seq;RNA-seq	6	Illumina HiSeq 2000 (Homo sapiens)
C   GSE68402	Chip-seq	26	Illumina MiSeq (Homo sapiens);Illumina HiSeq 2500 (Homo sapiens)
TCGA_LIHC_HBV	DNA methylation sequencing;RNA-seq	97	TCGA
C   GSE270130	Chip-seq	27	Illumina NovaSeq 6000 (Homo sapiens)
GSE224901	RNA-seq	21	Illumina NovaSeq 6000 (Homo sapiens)
C   GSE100400	Chip-seq;RNA-seq;4C_cccDNA	31	Illumina NextSeq 500 (Homo sapiens);Illumina NextSeq 500 (Mus musculus)
GSE173897	RNA-seq	95	Illumina HiSeq 4000 (Homo sapiens)
GSE262515	RNA-seq	21	Illumina HiSeq 2500 (Homo sapiens);Illumina HiSeq 2500 (Mus musculus)
GSE110345	RNA-seq	4	Illumina HiSeq 2500 (Homo sapiens)
C   GSE131257	ATAC-seq;RNA-seq	19	Illumina HiSeq 2500 (Homo sapiens)
GSE94660	RNA-seq	42	Illumina HiSeq 2500 (Homo sapiens)

• Genome binding/occupancy profiling

When the gene can detect a peak in the dataset, a peak plot will be displayed.

> Dataset: GSE35465 - ZNF423 peak across samples

Peak Plot

> Dataset: GSE68402 - ZNF423 peak across samples

Peak Plot

> Dataset: GSE270130 - ZNF423 peak across samples

Peak Plot

> Dataset: GSE100400 - ZNF423 peak across samples

Peak Plot

> Dataset: GSE131257 - ZNF423 peak across samples

Peak Plot