| 19733189 |
12064 |
Bdnf
|
Nerve |
We also studied any changes due to EA or social isolation in neurotrophic factors as nerve growth factor (NGF) or brain-derived neurotrophic factor (BDNF) known to have a role in regulating memory and learning processes. |
| 19733189 |
12064 |
Bdnf
|
Nerve |
We also studied any changes due to EA or social isolation in neurotrophic factors as nerve growth factor (NGF) or brain-derived neurotrophic factor (BDNF) known to have a role in regulating memory and learning processes. |
| 19733189 |
18049 |
Ngf
|
Nerve |
We also studied any changes due to EA or social isolation in neurotrophic factors as nerve growth factor (NGF) or brain-derived neurotrophic factor (BDNF) known to have a role in regulating memory and learning processes. |
| 22524543 |
11539 |
Adora1
|
Nerve |
Likewise, in the spared nerve injury (SNI) model of neuropathic pain, hPAP (250 mU) inhibited thermal and mechanical hypersensitivity for three days in the ipsilateral (injured) hindpaw of wild-type mice but not A1R-/- mice (Figure 4C,D). |
| 22524543 |
11539 |
Adora1
|
Nerve |
hPAP reduced nerve-injury induced thermal hyperalgesia for two days in wild-type but not A1R-/- mice (Figure 4E). |
| 22524543 |
56318 |
Acp3
|
Nerve |
Likewise, in the spared nerve injury (SNI) model of neuropathic pain, hPAP (250 mU) inhibited thermal and mechanical hypersensitivity for three days in the ipsilateral (injured) hindpaw of wild-type mice but not A1R-/- mice (Figure 4C,D). |
| 22524543 |
56318 |
Acp3
|
Nerve |
hPAP reduced nerve-injury induced thermal hyperalgesia for two days in wild-type but not A1R-/- mice (Figure 4E). |
| 22524543 |
56318 |
Acp3
|
Nerve |
In addition, injection of hPAP prior to nerve injury reduced mechanical allodynia for six days in wild-type mice (Figure 4F), three days longer than when hPAP was injected after nerve injury (Figure 4D). |
| 23097675 |
26417 |
Mapk3
|
Nerve |
Western blot results indicated that ion channel and TrpV1 expression in colorectum as well as ERK1/2 MAPK pathway activation in peripheral and central nerve system might be involved in this process. |
| 23097675 |
22223 |
Uchl1
|
Nerve |
PGP9.5 is in neurones and nerve fibers at all levels of the central and peripheral nervous system. |
| 23097675 |
193034 |
Trpv1
|
Nerve |
Western blot results indicated that ion channel and TrpV1 expression in colorectum as well as ERK1/2 MAPK pathway activation in peripheral and central nerve system might be involved in this process. |
| 24612851 |
55991 |
Panx1
|
Nerve |
The results showed that pannexin 1, connexin 43, P2Y1, and P2Y2 were expressed in nerve, muscle, and connective tissue. |
| 24612851 |
14609 |
Gja1
|
Nerve |
The results showed that pannexin 1, connexin 43, P2Y1, and P2Y2 were expressed in nerve, muscle, and connective tissue. |
| 24612851 |
18441 |
P2ry1
|
Nerve |
The results showed that pannexin 1, connexin 43, P2Y1, and P2Y2 were expressed in nerve, muscle, and connective tissue. |
| 24612851 |
18442 |
P2ry2
|
Nerve |
The results showed that pannexin 1, connexin 43, P2Y1, and P2Y2 were expressed in nerve, muscle, and connective tissue. |
| 31871478 |
21823 |
Th
|
Nerve |
To quantify TH-positive cells, we measured the OD values of TH-positive dopaminergic nerve fibers in the striatum (Figure 8) and counted the number of TH-positive dopaminergic neurons in the SNpc (Figure 9). |
| 34393735 |
18049 |
Ngf
|
Nerve |
In contrast, acupuncture stimulation suppressed nerve growth factor (NGF) expression induced by SDS. |
| 35138669 |
56318 |
Acp3
|
Nerve |
CONCLUSIONS: EA treatment alleviated peripheral nerve injury-induced mechanical pain hypersensitivity in mice by inhibiting membrane PAP degradation via reduced endocytosis and subsequently promote ATP dephosphorylation in DRGs. |
| 35579004 |
12064 |
Bdnf
|
Nerve |
METHODS: We compared the antidepressant effects of manual acupuncture (MA) stimulation at GV20 and Yintang, compared to acupuncture stimulation at two control point locations on the back of the mice (overlying the spinal column) and imipramine administration in a forced swimming (FS)-induced mouse model of depression, and examined the mRNA and protein expression of neurotrophic factors, including nerve growth factor (NGF), brain-derived neurotrophic factor (BDNF), neurotrophin (NT)-3, and NT-4/5 in the brains by real-time polymerase chain reaction in two different experimental schedules - preventive (MA given alongside FS modelling) and therapeutic (MA given after FS-induced depression was already established). |
| 35579004 |
12064 |
Bdnf
|
Nerve |
METHODS: We compared the antidepressant effects of manual acupuncture (MA) stimulation at GV20 and Yintang, compared to acupuncture stimulation at two control point locations on the back of the mice (overlying the spinal column) and imipramine administration in a forced swimming (FS)-induced mouse model of depression, and examined the mRNA and protein expression of neurotrophic factors, including nerve growth factor (NGF), brain-derived neurotrophic factor (BDNF), neurotrophin (NT)-3, and NT-4/5 in the brains by real-time polymerase chain reaction in two different experimental schedules - preventive (MA given alongside FS modelling) and therapeutic (MA given after FS-induced depression was already established). |
| 35579004 |
18049 |
Ngf
|
Nerve |
METHODS: We compared the antidepressant effects of manual acupuncture (MA) stimulation at GV20 and Yintang, compared to acupuncture stimulation at two control point locations on the back of the mice (overlying the spinal column) and imipramine administration in a forced swimming (FS)-induced mouse model of depression, and examined the mRNA and protein expression of neurotrophic factors, including nerve growth factor (NGF), brain-derived neurotrophic factor (BDNF), neurotrophin (NT)-3, and NT-4/5 in the brains by real-time polymerase chain reaction in two different experimental schedules - preventive (MA given alongside FS modelling) and therapeutic (MA given after FS-induced depression was already established). |
| 35579004 |
78405 |
Ntf5
|
Nerve |
METHODS: We compared the antidepressant effects of manual acupuncture (MA) stimulation at GV20 and Yintang, compared to acupuncture stimulation at two control point locations on the back of the mice (overlying the spinal column) and imipramine administration in a forced swimming (FS)-induced mouse model of depression, and examined the mRNA and protein expression of neurotrophic factors, including nerve growth factor (NGF), brain-derived neurotrophic factor (BDNF), neurotrophin (NT)-3, and NT-4/5 in the brains by real-time polymerase chain reaction in two different experimental schedules - preventive (MA given alongside FS modelling) and therapeutic (MA given after FS-induced depression was already established). |
| 11058557 |
310738 |
Ngf
|
Nerve |
Effects of electro-acupuncture on nerve growth factor and ovarian morphology in rats with experimentally induced polycystic ovaries. |
| 11058557 |
310738 |
Ngf
|
Nerve |
Nerve growth factor (NGF) is known to serve as a neurotrophin for both the sympathetic and the sensory nervous systems and to enhance the activity of catecholaminergic and possibly other neuron types. |
| 11058557 |
310738 |
Ngf
|
Nerve |
Effects of electro-acupuncture on nerve growth factor and ovarian morphology in rats with experimentally induced polycystic ovaries. |
| 11058557 |
310738 |
Ngf
|
Nerve |
Nerve growth factor (NGF) is known to serve as a neurotrophin for both the sympathetic and the sensory nervous systems and to enhance the activity of catecholaminergic and possibly other neuron types. |
| 11058557 |
310738 |
Ngf
|
Nerve |
Other evidence of neuronal involvement is that ovarian sympathetic innervation is under trophic control by nerve growth factor (NGF) |
| 23878591 |
65036 |
Bche
|
Nerve |
Cholinesterase-positive nerve fibers (Acher) with different thickness were clearly visible, surrounding the blood vessels in the arterial wall, which has the close relationship with the vascular smooth muscle (Figures 1(a) and 1(e)). |
| 23878591 |
65036 |
Bche
|
Nerve |
There are thick cholinesterase-positive nerve fibers near the vascular form into the sparse network. |
| 25074385 |
25712 |
Ifng
|
Nerve |
Since excessive release of interferon-gamma (IFN-gamma) after nerve injury transforms quiescent spinal microglia into an activated state with more neuropathic pain, associated with purinergic receptor P2X4 expression, it is possible that EA may mediate its analgesic effect by attenuating IFN-gamma release and subsequent generation of P2X4R(+) microglia. |
| 25074385 |
25712 |
Ifng
|
Nerve |
CONCLUSIONS: EA ameliorated tactile allodynia after peripheral nerve injury by down-regulating excessive expression of IFN-gamma in the spinal cord and subsequently reducing expression of P2X4R. |
| 25206406 |
24387 |
Gfap
|
Nerve |
Glial fibrillary acidic protein expression following electroacupuncture treatment in middle cerebral artery occluded rats. Glial fibrillary acidic protein positive cells were stained as brown yellow, yellow or light yellow, and staining was visible in cell bodies, nerve fibers and terminals. |
| 25206406 |
24387 |
Gfap
|
Nerve |
Glial fibrillary acidic protein positive cells were stained as brown yellow, yellow or light yellow, and staining was visible in cell bodies, nerve fibers and terminals. |
| 25878596 |
25496 |
Notch1
|
Nerve |
Notch pathway activation maintains neural stem cells in a proliferating state and increases nerve repair capacity. |
| 26148746 |
24241 |
Calca
|
Nerve |
Our results showed that SP and CGRP were expressed more highly on the cutaneous nerve fibers of LI4 after MA stimulation than that of the control. |
| 26148746 |
24241 |
Calca
|
Nerve |
The results indicated that local cutaneous nerve terminals and mast cells responded to MA with higher expression of SP and CGRP in nerve fibers, |
| 26148746 |
24241 |
Calca
|
Nerve |
in which we exposed sensory nerve fibers using substance P (SP) and CGRP, |
| 26148746 |
24241 |
Calca
|
Nerve |
We hypothesized that acupuncture stimulation could activate the cutaneous sensory nerves to propagate impulses and release inflammatory neuropeptides CGRP and SP, |
| 26148746 |
24241 |
Calca
|
Nerve |
(1) mast cells and blood vessels, (2) mast cells and SP-positive nerve fibers, (3) mast cells and CGRP-positive nerve fibers, (4) HA-expression on mast cells, and (5) 5-HT-expression on mast cells. |
| 26148746 |
24241 |
Calca
|
Nerve |
We used a similar procedure in the double immunohistochemical staining to examine the correlation between mast cells and SP or CGRP-positive nerve fibers, |
| 26148746 |
24241 |
Calca
|
Nerve |
Rabbit polyclonal anti-mast cell tryptase antibody and mouse monoclonal anti-CGRP antibody were employed to examine the correlation between mast cells and CGRP-positive nerve fibers. |
| 26148746 |
24241 |
Calca
|
Nerve |
After MA stimulation, the SP and CGRP were distributed more around the local nerve fibers, and mast cells tended to gather around the SP- and CGRP-positive nerve fibers |
| 26148746 |
24241 |
Calca
|
Nerve |
The correlation of mast cells and SP- or CGRP-positive nerve fibers in the area of LI4 were examined by double immunohistochemical staining (Fig. 3, Fig. 4). |
| 26148746 |
24241 |
Calca
|
Nerve |
In this study we examined the distributions of SP- and CGRP-positive nerve fibers and morphological and chemical changes of mast cells in the area of acupoint LI4 after MA stimulation. |
| 26148746 |
24241 |
Calca
|
Nerve |
(2) SP- and CGRP-positive nerve fibers responded to MA stimulation, displaying higher expression of SP and CGRP than those of the control, and, in turn, mast cells migrated toward SP- and CGRP-positive nerve fibers; |
| 26148746 |
24241 |
Calca
|
Nerve |
In this study the higher expression of SP and CGRP on cutaneous nerve fibers in the area of LI4 suggests that the nerve fibers might be responding to MA stimulation. |
| 26148746 |
24806 |
Tac1
|
Nerve |
in which we exposed sensory nerve fibers using substance P (SP) and CGRP, |
| 26148746 |
24806 |
Tac1
|
Nerve |
in which we exposed sensory nerve fibers using substance P (SP) and CGRP, |
| 26148746 |
24806 |
Tac1
|
Nerve |
Our results showed that SP and CGRP were expressed more highly on the cutaneous nerve fibers of LI4 after MA stimulation than that of the control. |
| 26148746 |
24806 |
Tac1
|
Nerve |
The results indicated that local cutaneous nerve terminals and mast cells responded to MA with higher expression of SP and CGRP in nerve fibers, |
| 26148746 |
24806 |
Tac1
|
Nerve |
We used a similar procedure in the double immunohistochemical staining to examine the correlation between mast cells and SP or CGRP-positive nerve fibers, |
| 26148746 |
24806 |
Tac1
|
Nerve |
After MA stimulation, the SP and CGRP were distributed more around the local nerve fibers, and mast cells tended to gather around the SP- and CGRP-positive nerve fibers |
| 26148746 |
24806 |
Tac1
|
Nerve |
(2) SP- and CGRP-positive nerve fibers responded to MA stimulation, displaying higher expression of SP and CGRP than those of the control, and, in turn, mast cells migrated toward SP- and CGRP-positive nerve fibers; |
| 26148746 |
24806 |
Tac1
|
Nerve |
In this study the higher expression of SP and CGRP on cutaneous nerve fibers in the area of LI4 suggests that the nerve fibers might be responding to MA stimulation. |
| 26148746 |
24806 |
Tac1
|
Nerve |
(2) nociceptive neuropeptides SP and CGRP are abundantly expressed in the nerve fibers to activate local blood vessels and mast cells (Bienenstock et al., 1991); |
| 26148746 |
24806 |
Tac1
|
Nerve |
MA stimulation induces high expression of nociceptive neuropeptides of SP and CGRP in the subepidermal nerve fibers, |
| 26631142 |
24806 |
Tac1
|
Nerve |
In addition, it is known that antidromic electrical stimulation of peripheral nerve at A or A+C fibers intensity results in the release of some neurotransmitters such as glutamate and neuropeptide such as substance P and calcitonin gene-related peptide from the central and peripheral terminals of primary afferents. |
| 26631142 |
24241 |
Calca
|
Nerve |
In addition, it is known that antidromic electrical stimulation of peripheral nerve at A or A+C fibers intensity results in the release of some neurotransmitters such as glutamate and neuropeptide such as substance P and calcitonin gene-related peptide from the central and peripheral terminals of primary afferents. |
| 27127487 |
170945 |
Chrna2
|
Nerve |
We found that area and the integrated optical density of the immunoreactivity for the acetylcholine receptor at the neuromuscular junction of the phrenic nerve was significantly increased following acupuncture treatment. |
| 27127487 |
170945 |
Chrna2
|
Nerve |
Compared with the control group, the averages of the immunofluorescence-positive area and the integrated optical density of the nicotinic AChR antibody immunoreactivity at neuromuscular junction in the phrenic nerve were lower in all three groups of rats with EAMG (P < 0.01). |
| 27127487 |
170945 |
Chrna2
|
Nerve |
Here, we used confocal laser scanning microscopy to examine the area and density of immunoreactivity for an antibody to the nicotinic acetylcholine receptor at the neuromuscular junction in the phrenic nerve of rats with experimental autoimmune myasthenia gravis following warming yang and invigorating qi acupuncture therapy. |
| 27664868 |
81687 |
Mmp9
|
Nerve |
Electroacupuncture alleviates nerve injury after cerebra ischemia in rats through inhibiting cell apoptosis and changing the balance of MMP-9/TIMP-1 expression. |
| 27664868 |
116510 |
Timp1
|
Nerve |
Electroacupuncture alleviates nerve injury after cerebra ischemia in rats through inhibiting cell apoptosis and changing the balance of MMP-9/TIMP-1 expression. |
| 28546432 |
29467 |
Ddit3
|
Nerve |
Inhibition of CHOP and JNK upregulation and reduction of nerve cell apoptosis may be the main mechanisms underlying the effects of acupuncture on heroin addiction-induced brain injury. |
| 28546432 |
116554 |
Mapk8
|
Nerve |
Inhibition of CHOP and JNK upregulation and reduction of nerve cell apoptosis may be the main mechanisms underlying the effects of acupuncture on heroin addiction-induced brain injury. |
| 28600329 |
24241 |
Calca
|
Nerve |
The SP- and CGRP-IR positive nerve fibres were also found between neuronal cell bodies. |
| 29033603 |
24241 |
Calca
|
Nerve |
These data suggest that ligation of the two branches of the sciatic nerve could increase the expression of CGRP and SP in a similar manner to the ligation of the trunk of the sciatic nerve. |
| 29436370 |
310738 |
Ngf
|
Nerve |
In total, 140 male Wistar rats were used; isoflurane-induced nociceptive response was evaluated using the von Frey test, serum calcium-binding protein beta (S100beta) levels and nerve growth factor (NGF) levels in the left sciatic nerve. |
| 29436370 |
310738 |
Ngf
|
Nerve |
There was an interaction between the independent variables: pain, treatments, and anesthesia in serum S100beta levels and NGF levels in the left sciatic nerve. |
| 29436370 |
310738 |
Ngf
|
Nerve |
Isoflurane enhanced the analgesic effects of Ac and EA and altered serum S100beta and left sciatic nerve NGF levels in rats with NP. |
| 34646326 |
170911 |
Pik3ca
|
Nerve |
Hyperalgesia is attenuated by inflammatory mediators that activate transient receptor potential vanilloid 1 (TRPV1), and TRPV1 is regulated by nerve growth factor (NGF)-induced phosphatidylinositol 3-kinase (PI3K)/Akt pathway. |
| 34646326 |
310738 |
Ngf
|
Nerve |
Hyperalgesia is attenuated by inflammatory mediators that activate transient receptor potential vanilloid 1 (TRPV1), and TRPV1 is regulated by nerve growth factor (NGF)-induced phosphatidylinositol 3-kinase (PI3K)/Akt pathway. |
| 34646326 |
24185 |
Akt1
|
Nerve |
Hyperalgesia is attenuated by inflammatory mediators that activate transient receptor potential vanilloid 1 (TRPV1), and TRPV1 is regulated by nerve growth factor (NGF)-induced phosphatidylinositol 3-kinase (PI3K)/Akt pathway. |
| 34646326 |
83810 |
Trpv1
|
Nerve |
Hyperalgesia is attenuated by inflammatory mediators that activate transient receptor potential vanilloid 1 (TRPV1), and TRPV1 is regulated by nerve growth factor (NGF)-induced phosphatidylinositol 3-kinase (PI3K)/Akt pathway. |
| 31217804 |
24604 |
Npy
|
Nerve |
Repeated DES did not significantly alter plasma levels of NPY released from sympathetic nerves (Figure 4(e)). |
| 31217804 |
24166 |
Adcyap1
|
Nerve |
To evaluate the effects of EA at GB20+GB34, GB20, and GB34 on parasympathetic nerve activation in our rat model, we assessed plasma levels of VIP and PACAP release from parasympathetic nerves. |
| 31217804 |
117064 |
Vip
|
Nerve |
To evaluate the effects of EA at GB20+GB34, GB20, and GB34 on parasympathetic nerve activation in our rat model, we assessed plasma levels of VIP and PACAP release from parasympathetic nerves. |
| 33398365 |
29659 |
P2rx4
|
Nerve |
In order to demonstrate the possibility that EA analgesia is mediated in part by P2X4R in hyperactive microglia, the present study performed mechanical withdrawal threshold (MWT) and thermal withdrawal latency (TWL) tests in male Sprague-Dawley rats that had undergone spinal nerve ligation (SNL). |
| 35100811 |
54250 |
Fgf2
|
Nerve |
Electroacupuncture suppresses spinal nerve ligation-induced neuropathic pain via regulation of synaptic plasticity through upregulation of basic fibroblast growth factor expression. |
| 35100811 |
54250 |
Fgf2
|
Nerve |
Evidence has suggested that basic fibroblast growth factor (bFGF) plays an important role in promoting nerve regeneration and can promote the expression of vascular endothelial growth factor (VEGF). |
| 35100811 |
83785 |
Vegfa
|
Nerve |
Evidence has suggested that basic fibroblast growth factor (bFGF) plays an important role in promoting nerve regeneration and can promote the expression of vascular endothelial growth factor (VEGF). |
| 30341024 |
83817 |
Ache
|
Nerve |
RESULTS: Compared with normal rats, there were a significant decline in lung function and discharge of the vagus nerve (P < 0.01), a marked sign of lung inflammation and an increase of ACh, AChE, IL-6 and TNF-alpha level in BALF or lung tissue (P < 0.05, P < 0.01) and higher expression of alpha7nAChR, JAK2, STAT3 and NF-kappaB (P < 0.05, P < 0.01) in the COPD rats. |
| 30341024 |
24498 |
Il6
|
Nerve |
RESULTS: Compared with normal rats, there were a significant decline in lung function and discharge of the vagus nerve (P < 0.01), a marked sign of lung inflammation and an increase of ACh, AChE, IL-6 and TNF-alpha level in BALF or lung tissue (P < 0.05, P < 0.01) and higher expression of alpha7nAChR, JAK2, STAT3 and NF-kappaB (P < 0.05, P < 0.01) in the COPD rats. |
| 30341024 |
24514 |
Jak2
|
Nerve |
RESULTS: Compared with normal rats, there were a significant decline in lung function and discharge of the vagus nerve (P < 0.01), a marked sign of lung inflammation and an increase of ACh, AChE, IL-6 and TNF-alpha level in BALF or lung tissue (P < 0.05, P < 0.01) and higher expression of alpha7nAChR, JAK2, STAT3 and NF-kappaB (P < 0.05, P < 0.01) in the COPD rats. |
| 30341024 |
25125 |
Stat3
|
Nerve |
RESULTS: Compared with normal rats, there were a significant decline in lung function and discharge of the vagus nerve (P < 0.01), a marked sign of lung inflammation and an increase of ACh, AChE, IL-6 and TNF-alpha level in BALF or lung tissue (P < 0.05, P < 0.01) and higher expression of alpha7nAChR, JAK2, STAT3 and NF-kappaB (P < 0.05, P < 0.01) in the COPD rats. |
| 30341024 |
24835 |
Tnf
|
Nerve |
RESULTS: Compared with normal rats, there were a significant decline in lung function and discharge of the vagus nerve (P < 0.01), a marked sign of lung inflammation and an increase of ACh, AChE, IL-6 and TNF-alpha level in BALF or lung tissue (P < 0.05, P < 0.01) and higher expression of alpha7nAChR, JAK2, STAT3 and NF-kappaB (P < 0.05, P < 0.01) in the COPD rats. |
| 30341024 |
25302 |
Chrna7
|
Nerve |
RESULTS: Compared with normal rats, there were a significant decline in lung function and discharge of the vagus nerve (P < 0.01), a marked sign of lung inflammation and an increase of ACh, AChE, IL-6 and TNF-alpha level in BALF or lung tissue (P < 0.05, P < 0.01) and higher expression of alpha7nAChR, JAK2, STAT3 and NF-kappaB (P < 0.05, P < 0.01) in the COPD rats. |
| 30341024 |
81736 |
Nfkb1
|
Nerve |
RESULTS: Compared with normal rats, there were a significant decline in lung function and discharge of the vagus nerve (P < 0.01), a marked sign of lung inflammation and an increase of ACh, AChE, IL-6 and TNF-alpha level in BALF or lung tissue (P < 0.05, P < 0.01) and higher expression of alpha7nAChR, JAK2, STAT3 and NF-kappaB (P < 0.05, P < 0.01) in the COPD rats. |
| 36651839 |
54250 |
Fgf2
|
Nerve |
Acupuncture combined with exercise training at different time points on nerve repair of cerebral ischemia-reperfusion injury in rats and its effects on the expressions of Nestin, bFGF and EGF. |
| 36651839 |
25313 |
Egf
|
Nerve |
Acupuncture combined with exercise training at different time points on nerve repair of cerebral ischemia-reperfusion injury in rats and its effects on the expressions of Nestin, bFGF and EGF. |
| 37384285 |
24241 |
Calca
|
Nerve |
To investigate whether the nerve fibers of the skin were chemically ablated by RTX, we double-stained the nerve fibers with anti-PGP 9.5 antibody (a marker for intraepidermal general nerve fibers) and anti-CGRP antibody (a marker for peripheral peptidergic nerve fibers). |
| 32956833 |
24806 |
Tac1
|
Nerve |
The roles of increased SP in Neuro-Sps were also investigated by using immunohistochemistry, in vivo single-fiber peripheral nerve recordings, and in vivo midbrain extracellular recordings. |
| 32956833 |
24806 |
Tac1
|
Nerve |
The Neuro-Sps showed an increased release of SP from afferent nerve terminals. |
| 32956833 |
24806 |
Tac1
|
Nerve |
Single fiber recordings of peripheral nerves showed that increased SP into the Neuro-Sps elevated the sensitivity of A- and C-fibers in response to acupuncture stimulation. |
| 32956833 |
24806 |
Tac1
|
Nerve |
To examine the increased release of SP from afferent nerves in Neuro-Sps, immunohistochemical detection of SP was performed on tissue samples from wrist areas of naive (Control) and IMH rats (Fig. |
| 32956833 |
24806 |
Tac1
|
Nerve |
To determine whether SP increases the sensitivity of primary afferent fibers to acupuncture, single fiber recordings of peripheral nerves were performed in 15 somatic afferent neurons innervating the wrist area in 15 naive rats (Fig. |
| 29972006 |
29423 |
Gap43
|
Nerve |
The level of nerve growth associated protein (GAP-43) and energy metabolism-related protein monocarboxylate transporter protien 1(MCT 1) were detected by Western blot. |
| 29972006 |
29423 |
Gap43
|
Nerve |
CONCLUSION: Acupuncture combined with NGF could improve the neurobehavioral ability of cerebral palsy infant rats, inhibit the nerve cell apoptosis and improve the brain tissue injure and energy metabolism by up-regulating the expressions of GAP-43 and MCT 1. |
| 29972006 |
25027 |
Slc16a1
|
Nerve |
The level of nerve growth associated protein (GAP-43) and energy metabolism-related protein monocarboxylate transporter protien 1(MCT 1) were detected by Western blot. |
| 29972006 |
25027 |
Slc16a1
|
Nerve |
CONCLUSION: Acupuncture combined with NGF could improve the neurobehavioral ability of cerebral palsy infant rats, inhibit the nerve cell apoptosis and improve the brain tissue injure and energy metabolism by up-regulating the expressions of GAP-43 and MCT 1. |
| 29972006 |
310738 |
Ngf
|
Nerve |
[Study of acupuncture combined with rat nerve growth factor on neurobehavioral ability of cerebral palsy infant rats and its brain tissue growth and metabolism associated proteins]. |
| 29972006 |
310738 |
Ngf
|
Nerve |
OBJECTIVE: To study the effects of acupuncture combined with rat nerve growth factor (NGF) on the cerebral palsy infant rats and the proteins which associated with growth, apoptosis and metabolism. |
| 29972006 |
310738 |
Ngf
|
Nerve |
CONCLUSION: Acupuncture combined with NGF could improve the neurobehavioral ability of cerebral palsy infant rats, inhibit the nerve cell apoptosis and improve the brain tissue injure and energy metabolism by up-regulating the expressions of GAP-43 and MCT 1. |
| 34405366 |
25319 |
Fth1
|
Nerve |
In order to determine whether the enhanced degree of FTH1 was involved in mitigating nerve cell lipid peroxidation damage induced by surplus iron, MDA was assayed at day 3 following ICH, i.e. |
| 34405366 |
25319 |
Fth1
|
Nerve |
In combination, these data infer that SA treatment is efficacious in reducing nerve cell lipid peroxidation damage as a result of excess iron through the amplification of FTH1 expression. |
| 34405366 |
287847 |
Rbfox3
|
Nerve |
NeuN expression was established using Western blot assay to affirm that nerve cells were susceptible to damage following ICH (Fig. |
| 36422883 |
56718 |
Mtor
|
Nerve |
Acupuncture promotes nerve repair through the benign regulation of mTOR-mediated neuronal autophagy in traumatic brain injury rats Acupuncture promotes nerve repair through the benign regulation of mTOR-mediated neuronal autophagy in TBI rats |
| 36046956 |
29260 |
Tlr4
|
Nerve |
CONCLUSION: The results of this study demonstrate that one of the mechanisms through which acupuncture mitigates neuroinflammation and promotes nerve repair in TBI rats may be inhibition of M1 phenotypic polarization and promotion of M2 phenotypic polarization through inhibition of the TLR4/TRIF/MyD88 signaling pathway. |
| 36046956 |
94196 |
Rnf138
|
Nerve |
CONCLUSION: The results of this study demonstrate that one of the mechanisms through which acupuncture mitigates neuroinflammation and promotes nerve repair in TBI rats may be inhibition of M1 phenotypic polarization and promotion of M2 phenotypic polarization through inhibition of the TLR4/TRIF/MyD88 signaling pathway. |
| 36046956 |
301059 |
Myd88
|
Nerve |
CONCLUSION: The results of this study demonstrate that one of the mechanisms through which acupuncture mitigates neuroinflammation and promotes nerve repair in TBI rats may be inhibition of M1 phenotypic polarization and promotion of M2 phenotypic polarization through inhibition of the TLR4/TRIF/MyD88 signaling pathway. |
| 29623933 |
310738 |
Ngf
|
Nerve |
Electroacupuncture and moxibustion promote regeneration of injured sciatic nerve through Schwann cell proliferation and nerve growth factor secretion |
| 29623933 |
310738 |
Ngf
|
Nerve |
We used immunohistochemistry to observe changes in the expression of S100:a specific marker for Schwann cells:and an enzyme-linked immunosorbent assay to detect serum level of nerve growth factor. |
| 29623933 |
310738 |
Ngf
|
Nerve |
Results showed that compared with the model-only group, sciatic functional index, recovery rate of conduction velocity, diameter recovery of the gastrocnemius muscle fibers, number of S100-immunoreactive cells, and level of nerve growth factor were greater in the electroacupuncture and moxibustion groups. |
| 29623933 |
310738 |
Ngf
|
Nerve |
These findings indicate that electroacupuncture and moxibustion promoted nerve regeneration and functional recovery; its mechanism might be associated with the enhancement of Schwann cell proliferation and upregulation of nerve growth factor. |
| 29623933 |
310738 |
Ngf
|
Nerve |
NGF is a neurotrophic factor that promotes nerve regeneration after peripheral nerve injury (Tang et al., 2013). |
| 30884162 |
156117 |
Casp12
|
Nerve |
Immunofluorescence and western blot analysis were used to determine GRP78 and caspase-12 levels in sciatic nerves. |
| 30884162 |
156117 |
Casp12
|
Nerve |
Moreover, electroacupuncture significantly downregulated GRP78 and caspase-12 and reduced cell apoptosis of sciatic nerves in DPN rats. |
| 30884162 |
156117 |
Casp12
|
Nerve |
CONCLUSIONS: Electroacupuncture improved DPN by downregulating GRP78 and caspase-12 and reducing cell apoptosis of sciatic nerves in STZ-diabetic rats, and further inhibited the occurrence of endoplasmic reticulum stress, thus preventing sciatic nerve injuries. |
| 30884162 |
25617 |
Hspa5
|
Nerve |
Immunofluorescence and western blot analysis were used to determine GRP78 and caspase-12 levels in sciatic nerves. |
| 30884162 |
25617 |
Hspa5
|
Nerve |
Moreover, electroacupuncture significantly downregulated GRP78 and caspase-12 and reduced cell apoptosis of sciatic nerves in DPN rats. |
| 30884162 |
25617 |
Hspa5
|
Nerve |
CONCLUSIONS: Electroacupuncture improved DPN by downregulating GRP78 and caspase-12 and reducing cell apoptosis of sciatic nerves in STZ-diabetic rats, and further inhibited the occurrence of endoplasmic reticulum stress, thus preventing sciatic nerve injuries. |
| 36522251 |
314322 |
Fos
|
Nerve |
Finally, the activities of brain regions related to autonomic nerve regulation were assessed by c-Fos immunofluorescence and multichannel recording. |
| 30872987 |
25246 |
Bsg
|
Nerve |
While acupuncture at HT7 attenuated cocaine-induced enhancement of locomotor activity, such effects were inhibited by pretreatment of bupivacaine, but not collagenase, indicating mediation of the afferent nerve [one-way ANOVA, F(3, 21) = 4.998; *p < 0.05 vs. |
| 30872987 |
29545 |
Uchl1
|
Nerve |
On the other hand, in a quantitative immunohistochemical analysis for PGP 9.5, a marker for nerve fibers (Beiswenger et al.,), the morphological changes of the peripheral nerve were not observed in collagenase-treated skin compared to the normal group (Figures 5C,D). |
| 35579008 |
24241 |
Calca
|
Nerve |
Here, calcitonin gene-related peptide (CGRP), tyrosine hydroxylase (TH) and vesicular acetylcholine transporter (VAChT) were used to label the sensory, sympathetic and parasympathetic nerve fibers, respectively. |
| 35579008 |
24241 |
Calca
|
Nerve |
RESULTS: The CGRP+ sensory, TH+ sympathetic and VAChT+ parasympathetic nerve fibers were simultaneously demonstrated in the local tissues at GB14, ST2 and ST6. |
| 35579008 |
24241 |
Calca
|
Nerve |
CONCLUSION: Our study demonstrated the sensory and autonomic innervation of the local tissues at GB14, ST2 and ST6, providing neurochemical evidence indicating that the CGRP+ sensory, TH+ sympathetic and VAChT+ parasympathetic nerve fibers form a neural network at these point locations that may respond to acupuncture stimulation. |
| 35579008 |
60422 |
Slc18a3
|
Nerve |
Here, calcitonin gene-related peptide (CGRP), tyrosine hydroxylase (TH) and vesicular acetylcholine transporter (VAChT) were used to label the sensory, sympathetic and parasympathetic nerve fibers, respectively. |
| 35579008 |
60422 |
Slc18a3
|
Nerve |
RESULTS: The CGRP+ sensory, TH+ sympathetic and VAChT+ parasympathetic nerve fibers were simultaneously demonstrated in the local tissues at GB14, ST2 and ST6. |
| 35579008 |
60422 |
Slc18a3
|
Nerve |
CONCLUSION: Our study demonstrated the sensory and autonomic innervation of the local tissues at GB14, ST2 and ST6, providing neurochemical evidence indicating that the CGRP+ sensory, TH+ sympathetic and VAChT+ parasympathetic nerve fibers form a neural network at these point locations that may respond to acupuncture stimulation. |
| 2469996 |
24806 |
Tac1
|
Nerve |
It has been shown that nerve fibers containing SP, neurokinin A (NKA) and CGRP are found in the human skin [4]. |
| 8791904 |
24806 |
Tac1
|
Nerve |
Neurogenic Inflammation, includes vasodilation, the increase of vasal permeability and edema due to the release of neuromediators from nerve endings.The aim of this study is to verify the effect of acupuncture on the peripheral release of Substance P due to the injection of capsaicin in rat paw. |
| 8823756 |
|
|
Nerve |
Neurogenic inflammation and other local efferent functions of the capsaicin-sensitive nerve endings is well established. Here, we describe evidence for a systemic neurogenic anti-inflammatory effect initiated in the rat by this local response. |
| 9048220 |
|
|
Nerve |
The effects of acupuncture-like stimulation of the abdomen and a hindlimb on the secretion rates of adrenal medullary catecholamine hormones (adrenaline and noradrenaline) and adrenal sympathetic efferent nerve activity were studied using urethane-anesthetized rats. |
| 14671415 |
310738 |
Ngf
|
Nerve |
There is some evidence that nerve growth factor (NGF) is involved in the pathogenesis of PCOS. |
| 17359642 |
116510 |
Timp1
|
Nerve |
Compared to control group, three cytokines, interleukin-6 (IL-6), beta-nerve growth factor (beta-NGF) and tissue inhibitors of metalloproteinase-1 (TIMP-1), showed significantly decreased expression levels in the acupuncture group. |
| 17359642 |
24498 |
Il6
|
Nerve |
Compared to control group, three cytokines, interleukin-6 (IL-6), beta-nerve growth factor (beta-NGF) and tissue inhibitors of metalloproteinase-1 (TIMP-1), showed significantly decreased expression levels in the acupuncture group. |
| 17359642 |
310738 |
Ngf
|
Nerve |
Compared to control group, three cytokines, interleukin-6 (IL-6), beta-nerve growth factor (beta-NGF) and tissue inhibitors of metalloproteinase-1 (TIMP-1), showed significantly decreased expression levels in the acupuncture group. |
| 17359642 |
116510 |
Timp1
|
Nerve |
Compared to control group, three cytokines, interleukin-6 (IL-6), beta-nerve growth factor (beta-NGF) and tissue inhibitors of metalloproteinase-1 (TIMP-1), showed significantly decreased expression levels in the acupuncture group. |
| 17645478 |
100009276 |
MLN
|
Nerve |
Motilin in plasma, cholecystokinin (CCK) in serum, the activity of acetylcholine esterase, nitric oxide synthase (NOS), and the vesicle of nerve endings in the stomach tissue and jejunum were investigated. |
| 17645478 |
100009243 |
NOS1
|
Nerve |
In our study, we focused on motilin, CCK, NOS, and cholinergic nerves. |
| 19387577 |
310738 |
Ngf
|
Nerve |
Our previous study on the role of Korean red ginseng total saponins in a steroid-induced PCO rat model demonstrated that electro-acupuncture modulates nerve growth factor (NGF) concentration in the ovaries. |
| 19556171 |
24505 |
Ins1
|
Nerve |
These results show that EA in diabetic rats has no effect on plasma glucose concentration while it augments the responsiveness to insulin, and we show that this occurs via a mechanism that involves the somatic afferent nerves. |
| 20654703 |
29527 |
Ptgs2
|
Nerve |
Our recent study has shown that it may inhibit cyclooxygenase-2 (COX-2) in the spinal dorsal horn where COX-2 is upregulated after the development of neuropathic pain following spinal nerve ligation (SNL). |
| 21470565 |
81651 |
Cspg4
|
Nerve |
Compared with the sham group, more NG2-positive OPCs were distributed between neurofilament (NF)-positive nerve fibres or closely associated with them in the lesion site and nearby tissue. |
| 21470565 |
116690 |
Nfasc
|
Nerve |
Compared with the sham group, more NG2-positive OPCs were distributed between neurofilament (NF)-positive nerve fibres or closely associated with them in the lesion site and nearby tissue. |
| 24875645 |
100348561 |
MAPK3
|
Nerve |
Our study suggests that a potential mechanism by which acupuncture has an antihypertensive effect and can significantly halt deteriorating renal function due to cBSA GN might be mediated by inhibiting the Erk1/2 MAPK pathway to reduce renal sympathetic nerve activity (RSNA). |
| 24875645 |
100347345 |
MAPK1
|
Nerve |
Our study suggests that a potential mechanism by which acupuncture has an antihypertensive effect and can significantly halt deteriorating renal function due to cBSA GN might be mediated by inhibiting the Erk1/2 MAPK pathway to reduce renal sympathetic nerve activity (RSNA). |
| 33478541 |
103350089 |
NGF
|
Nerve |
Effects of exogenous nerve growth factor on the expression of BMP-9 and VEGF in the healing of rabbit mandible fracture with local nerve injury |
| 33478541 |
100008899 |
VEGFA
|
Nerve |
Effects of exogenous nerve growth factor on the expression of BMP-9 and VEGF in the healing of rabbit mandible fracture with local nerve injury |
