Gene symbol: Kiss1

Also known as: Eseptin

Organism: Rattus norvegicus

Summary: Enables kisspeptin receptor binding activity. Involved in several processes, including generation of ovulation cycle rhythm; positive regulation of cell communication; and positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway. Located in several cellular components, including apical plasma membrane; extracellular space; and neuronal cell body. Human ortholog(s) of this gene implicated in hypogonadotropic hypogonadism 13 with or without anosmia. Orthologous to human KISS1 (KiSS-1 metastasis suppressor). [provided by Alliance of Genome Resources, Apr 2022]

NCBI gene ID: 289023 EnsemblRapid:ENSRNOG00000047481 AllianceGenome:RGD:727850


GO Annotation


Category Term ID Term description
Process GO:0000003 Reproduction
Process GO:0001890 Placenta development
Process GO:0001893 Maternal placenta development
Process GO:0002791 Regulation of peptide secretion
Process GO:0002793 Positive regulation of peptide secretion
Process GO:0003006 Developmental process involved in reproduction
Process GO:0007154 Cell communication
Process GO:0007165 Signal transduction
Process GO:0007186 G protein-coupled receptor signaling pathway
Process GO:0007200 Phospholipase C-activating G protein-coupled receptor signaling pathway
Process GO:0007204 Positive regulation of cytosolic calcium ion concentration
Process GO:0007275 Multicellular organism development
Process GO:0007565 Female pregnancy
Process GO:0008285 Negative regulation of cell population proliferation
Process GO:0009888 Tissue development
Process GO:0009966 Regulation of signal transduction
Process GO:0009967 Positive regulation of signal transduction
Process GO:0009987 Cellular process
Process GO:0010646 Regulation of cell communication
Process GO:0010647 Positive regulation of cell communication
Process GO:0010817 Regulation of hormone levels
Process GO:0022414 Reproductive process
Process GO:0022602 Ovulation cycle process
Process GO:0023051 Regulation of signaling
Process GO:0023052 Signaling
Process GO:0023056 Positive regulation of signaling
Process GO:0030334 Regulation of cell migration
Process GO:0030336 Negative regulation of cell migration
Process GO:0032276 Regulation of gonadotropin secretion
Process GO:0032278 Positive regulation of gonadotropin secretion
Process GO:0032501 Multicellular organismal process
Process GO:0032502 Developmental process
Process GO:0032504 Multicellular organism reproduction
Process GO:0032879 Regulation of localization
Process GO:0033684 Regulation of luteinizing hormone secretion
Process GO:0033686 Positive regulation of luteinizing hormone secretion
Process GO:0040012 Regulation of locomotion
Process GO:0040013 Negative regulation of locomotion
Process GO:0042127 Regulation of cell population proliferation
Process GO:0042698 Ovulation cycle
Process GO:0043408 Regulation of MAPK cascade
Process GO:0043410 Positive regulation of MAPK cascade
Process GO:0044057 Regulation of system process
Process GO:0044060 Regulation of endocrine process
Process GO:0044703 Multi-organism reproductive process
Process GO:0044706 Multi-multicellular organism process
Process GO:0046697 Decidualization
Process GO:0046883 Regulation of hormone secretion
Process GO:0046887 Positive regulation of hormone secretion
Process GO:0048511 Rhythmic process
Process GO:0048513 Animal organ development
Process GO:0048518 Positive regulation of biological process
Process GO:0048519 Negative regulation of biological process
Process GO:0048522 Positive regulation of cellular process
Process GO:0048523 Negative regulation of cellular process
Process GO:0048583 Regulation of response to stimulus
Process GO:0048584 Positive regulation of response to stimulus
Process GO:0048608 Reproductive structure development
Process GO:0048609 Multicellular organismal reproductive process
Process GO:0048731 System development
Process GO:0048856 Anatomical structure development
Process GO:0050789 Regulation of biological process
Process GO:0050794 Regulation of cellular process
Process GO:0050804 Modulation of chemical synaptic transmission
Process GO:0050806 Positive regulation of synaptic transmission
Process GO:0050896 Response to stimulus
Process GO:0051046 Regulation of secretion
Process GO:0051047 Positive regulation of secretion
Process GO:0051049 Regulation of transport
Process GO:0051050 Positive regulation of transport
Process GO:0051239 Regulation of multicellular organismal process
Process GO:0051240 Positive regulation of multicellular organismal process
Process GO:0051482 Positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway
Process GO:0051716 Cellular response to stimulus
Process GO:0060112 Generation of ovulation cycle rhythm
Process GO:0060123 Regulation of growth hormone secretion
Process GO:0060124 Positive regulation of growth hormone secretion
Process GO:0060135 Maternal process involved in female pregnancy
Process GO:0061458 Reproductive system development
Process GO:0065007 Biological regulation
Process GO:0065008 Regulation of biological quality
Process GO:0090087 Regulation of peptide transport
Process GO:0090276 Regulation of peptide hormone secretion
Process GO:0090277 Positive regulation of peptide hormone secretion
Process GO:0099177 Regulation of trans-synaptic signaling
Process GO:1902531 Regulation of intracellular signal transduction
Process GO:1902533 Positive regulation of intracellular signal transduction
Process GO:1903530 Regulation of secretion by cell
Process GO:1903532 Positive regulation of secretion by cell
Process GO:2000145 Regulation of cell motility
Process GO:2000146 Negative regulation of cell motility
Component GO:0005576 Extracellular region
Component GO:0005615 Extracellular space
Component GO:0005622 Intracellular anatomical structure
Component GO:0005737 Cytoplasm
Component GO:0005886 Plasma membrane
Component GO:0016020 Membrane
Component GO:0016324 Apical plasma membrane
Component GO:0036477 Somatodendritic compartment
Component GO:0042995 Cell projection
Component GO:0043005 Neuron projection
Component GO:0043025 Neuronal cell body
Component GO:0044297 Cell body
Component GO:0045177 Apical part of cell
Component GO:0071944 Cell periphery
Component GO:0098590 Plasma membrane region
Component GO:0110165 Cellular anatomical entity
Component GO:0120025 Plasma membrane bounded cell projection
Function GO:0001664 G protein-coupled receptor binding
Function GO:0005102 Signaling receptor binding
Function GO:0005488 Binding
Function GO:0005515 Protein binding
Function GO:0031773 Kisspeptin receptor binding
Function GO:0071855 Neuropeptide receptor binding

Pathway annotation


Category Term ID Term description
RCTM RNO-162582 Signal Transduction
RCTM RNO-372790 Signaling by GPCR
RCTM RNO-373076 Class A/1 (Rhodopsin-like receptors)
RCTM RNO-375276 Peptide ligand-binding receptors
RCTM RNO-388396 GPCR downstream signalling
RCTM RNO-416476 G alpha (q) signalling events
RCTM RNO-500792 GPCR ligand binding

Expression profile of Kiss1 in omics data



ID GSE100499
Title Exploring acupuncture mechanism in preconditioning of IRI
Organism Rattus norvegicus
GSM Sample info Characteristics Value
GSM2685201 MX1 tissue: Myocardium gender: male 4.3628182
GSM2685202 MX2 tissue: Myocardium gender: female 4.4743385
GSM2685203 MX3 tissue: Myocardium gender: female 3.6610658
GSM2685204 MX4 tissue: Myocardium gender: male 4.2817626
GSM2685205 DZ1 tissue: Myocardium gender: male 4.3726788
GSM2685206 DZ2 tissue: Myocardium gender: male 4.602354
GSM2685207 DZ3 tissue: Myocardium gender: female 4.095042
GSM2685208 DZ4 tissue: Myocardium gender: female 3.8836045
GSM2685209 JJ1 tissue: Myocardium gender: male 4.4916506
GSM2685210 JJ2 tissue: Myocardium gender: female 5.163313
GSM2685211 JJ3 tissue: Myocardium gender: female 4.511131
GSM2685212 JJ4 tissue: Myocardium gender: male 4.296642
GSM2685213 NG1 tissue: Myocardium gender: male 7.3250213
GSM2685214 NG2 tissue: Myocardium gender: female 4.2420607
GSM2685215 NG3 tissue: Myocardium gender: male 4.19902
GSM2685216 NG4 tissue: Myocardium gender: female 4.6805105
GSM2685217 YL1 tissue: Myocardium gender: male 3.4044175
GSM2685218 YL2 tissue: Myocardium gender: male 2.740888
GSM2685219 YL3 tissue: Myocardium gender: female 3.3018079
GSM2685220 YL4 tissue: Myocardium gender: female 2.5710938
GSM2685221 QC1 tissue: Myocardium gender: male 2.4375904
GSM2685222 QC2 tissue: Myocardium gender: male 2.7012255
GSM2685223 QC3 tissue: Myocardium gender: female 4.3285756
GSM2685224 QC4 tissue: Myocardium gender: female 3.8855171

ID GSE138454
Title Impact of inflammation on hepatic subcellular energetics in anesthetized rats
Organism Rattus norvegicus
GSM Sample info Characteristics Value
GSM4108997 Sample 1 Isoflurane sepsis anesthetic background: Isoflurane strain: Sprague-Dawley age: 10 weeks old sepsis/control: sepsis gender: male 5.0
GSM4108998 Sample 2 Isoflurane sepsis anesthetic background: Isoflurane strain: Sprague-Dawley age: 10 weeks old sepsis/control: sepsis gender: male 2.0
GSM4108999 Sample 3 Isoflurane sepsis anesthetic background: Isoflurane strain: Sprague-Dawley age: 10 weeks old sepsis/control: sepsis gender: male 2.0
GSM4109000 Sample 4 Isoflurane sepsis anesthetic background: Isoflurane strain: Sprague-Dawley age: 10 weeks old sepsis/control: sepsis gender: male 1.0
GSM4109001 Sample 5 Isoflurane control anesthetic background: Isoflurane strain: Sprague-Dawley age: 10 weeks old sepsis/control: control gender: male 15.0
GSM4109002 Sample 6 Isoflurane control anesthetic background: Isoflurane strain: Sprague-Dawley age: 10 weeks old sepsis/control: control gender: male 16.0
GSM4109003 Sample 7 Isoflurane control anesthetic background: Isoflurane strain: Sprague-Dawley age: 10 weeks old sepsis/control: control gender: male 10.0
GSM4109004 Sample 8 Isoflurane control anesthetic background: Isoflurane strain: Sprague-Dawley age: 10 weeks old sepsis/control: control gender: male 14.0
GSM4109005 Sample9 Propofol sepsis anesthetic background: Propofol strain: Sprague-Dawley age: 10 weeks old sepsis/control: sepsis gender: male 1.0
GSM4109006 Sample10 Propofol sepsis anesthetic background: Propofol strain: Sprague-Dawley age: 10 weeks old sepsis/control: sepsis gender: male 4.0
GSM4109007 Sample11 Propofol sepsis anesthetic background: Propofol strain: Sprague-Dawley age: 10 weeks old sepsis/control: sepsis gender: male 5.0
GSM4109008 Sample12 Propofol sepsis anesthetic background: Propofol strain: Sprague-Dawley age: 10 weeks old sepsis/control: sepsis gender: male 6.0
GSM4109009 Sample13 Propofol control anesthetic background: Propofol strain: Sprague-Dawley age: 10 weeks old sepsis/control: control gender: male 0.0
GSM4109010 Sample14 Propofol control anesthetic background: Propofol strain: Sprague-Dawley age: 10 weeks old sepsis/control: control gender: male 7.0
GSM4109011 Sample 15 Propofol control anesthetic background: Propofol strain: Sprague-Dawley age: 10 weeks old sepsis/control: control gender: male 9.0
GSM4109012 Sample16 Propofol control anesthetic background: Propofol strain: Sprague-Dawley age: 10 weeks old sepsis/control: control gender: male 6.0

ID GSE143895
Title GPR160 de-orphanization reveals critical roles in neuropathic pain in rodents
Organism Rattus norvegicus
GSM Sample info Characteristics Value
GSM4276356 dhsc01 strain: Sprague Dawley tissue: DHSC treatment: CCI 0.0
GSM4276357 dhsc03 strain: Sprague Dawley tissue: DHSC treatment: CCI 1.363
GSM4276358 dhsc05 strain: Sprague Dawley tissue: DHSC treatment: CCI 0.671
GSM4276359 dhsc13 strain: Sprague Dawley tissue: DHSC treatment: SHAM 0.0
GSM4276360 dhsc15 strain: Sprague Dawley tissue: DHSC treatment: SHAM 0.618

ID GSE21258
Title Transcript Profiling of Spinal Dorsal Horn in Response to Electroacupuncture on Rats at 1h
Organism Rattus norvegicus
GSM Sample info Characteristics Value
GSM531353 2Hz_HR_1h_DH1 rat time point: 1h strain: Sprague-Dawley tissue type: spinal dorsal horn frequency: 2Hz group: high responder (HR) rats;strain: Sprague-Dawley reference: rats sacrificed after stayed in their home cages without receiving electroacupuncture stimulation. 0.0
GSM531354 2Hz_HR_1h_DH2 rat time point: 1h strain: Sprague-Dawley tissue type: spinal dorsal horn frequency: 2Hz group: high responder (HR) rats;strain: Sprague-Dawley reference: rats sacrificed after stayed in their home cages without receiving electroacupuncture stimulation. 0.0
GSM531355 2Hz_HR_1h_DH3 rat time point: 1h strain: Sprague-Dawley tissue type: spinal dorsal horn frequency: 2Hz group: high responder (HR) rats;strain: Sprague-Dawley reference: rats sacrificed after stayed in their home cages without receiving electroacupuncture stimulation. 0.0
GSM531356 2Hz_HR_1h_DH4 rat time point: 1h strain: Sprague-Dawley tissue type: spinal dorsal horn frequency: 2Hz group: high responder (HR) rats;strain: Sprague-Dawley reference: rats sacrificed after stayed in their home cages without receiving electroacupuncture stimulation. 0.0
GSM531357 2Hz_HR_1h_DH5 rat time point: 1h strain: Sprague-Dawley tissue type: spinal dorsal horn frequency: 2Hz group: high responder (HR) rats;strain: Sprague-Dawley reference: rats sacrificed after stayed in their home cages without receiving electroacupuncture stimulation. 0.0
GSM531358 2Hz_LR_1h_DH1 rat time point: 1h strain: Sprague-Dawley tissue type: spinal dorsal horn frequency: 2Hz group: low responder (LR) rats;strain: Sprague-Dawley reference: rats sacrificed after stayed in their home cages without receiving electroacupuncture stimulation. 0.0
GSM531359 2Hz_LR_1h_DH2 rat time point: 1h strain: Sprague-Dawley tissue type: spinal dorsal horn frequency: 2Hz group: low responder (LR) rats;strain: Sprague-Dawley reference: rats sacrificed after stayed in their home cages without receiving electroacupuncture stimulation. 0.0
GSM531360 2Hz_LR_1h_DH3 rat time point: 1h strain: Sprague-Dawley tissue type: spinal dorsal horn frequency: 2Hz group: low responder (LR) rats;strain: Sprague-Dawley reference: rats sacrificed after stayed in their home cages without receiving electroacupuncture stimulation. 0.0
GSM531361 2Hz_LR_1h_DH4 rat time point: 1h strain: Sprague-Dawley tissue type: spinal dorsal horn frequency: 2Hz group: low responder (LR) rats;strain: Sprague-Dawley reference: rats sacrificed after stayed in their home cages without receiving electroacupuncture stimulation. 0.0
GSM531362 100Hz_HR_1h_DH1 rat time point: 1h strain: Sprague-Dawley tissue type: spinal dorsal horn frequency: 100Hz group: high responder (HR) rats;strain: Sprague-Dawley reference: rats sacrificed after stayed in their home cages without receiving electroacupuncture stimulation. 0.0
GSM531363 100Hz_HR_1h_DH2 rat time point: 1h strain: Sprague-Dawley tissue type: spinal dorsal horn frequency: 100Hz group: high responder (HR) rats;strain: Sprague-Dawley reference: rats sacrificed after stayed in their home cages without receiving electroacupuncture stimulation. 0.0
GSM531364 100Hz_HR_1h_DH3 rat time point: 1h strain: Sprague-Dawley tissue type: spinal dorsal horn frequency: 100Hz group: high responder (HR) rats;strain: Sprague-Dawley reference: rats sacrificed after stayed in their home cages without receiving electroacupuncture stimulation. 0.0
GSM531365 100Hz_HR_1h_DH4 rat time point: 1h strain: Sprague-Dawley tissue type: spinal dorsal horn frequency: 100Hz group: high responder (HR) rats;strain: Sprague-Dawley reference: rats sacrificed after stayed in their home cages without receiving electroacupuncture stimulation. 0.0
GSM531366 100Hz_HR_1h_DH5 rat time point: 1h strain: Sprague-Dawley tissue type: spinal dorsal horn frequency: 100Hz group: high responder (HR) rats;strain: Sprague-Dawley reference: rats sacrificed after stayed in their home cages without receiving electroacupuncture stimulation. 0.0
GSM531367 100Hz_LR_1h_DH1 rat time point: 1h;strain: Sprague-Dawley reference: rats sacrificed after stayed in their home cages without receiving electroacupuncture stimulation. strain: Sprague-Dawley tissue type: spinal dorsal horn frequency: 100Hz group: low responder (LR) rats 0.0
GSM531368 100Hz_LR_1h_DH2 rat time point: 1h strain: Sprague-Dawley tissue type: spinal dorsal horn frequency: 100Hz group: low responder (LR) rats;strain: Sprague-Dawley reference: rats sacrificed after stayed in their home cages without receiving electroacupuncture stimulation. 0.0
GSM531369 100Hz_LR_1h_DH3 rat time point: 1h strain: Sprague-Dawley tissue type: spinal dorsal horn frequency: 100Hz group: low responder (LR) rats;strain: Sprague-Dawley reference: rats sacrificed after stayed in their home cages without receiving electroacupuncture stimulation. 0.0
GSM531370 100Hz_LR_1h_DH4 rat time point: 1h strain: Sprague-Dawley tissue type: spinal dorsal horn frequency: 100Hz group: low responder (LR) rats;strain: Sprague-Dawley reference: rats sacrificed after stayed in their home cages without receiving electroacupuncture stimulation. 0.0
GSM531371 100Hz_LR_1h_DH5 rat time point: 1h strain: Sprague-Dawley tissue type: spinal dorsal horn frequency: 100Hz group: low responder (LR) rats;strain: Sprague-Dawley reference: rats sacrificed after stayed in their home cages without receiving electroacupuncture stimulation. 0.0

ID GSE21733
Title Transcript Profiling of Spinal Dorsal Horn in Response to Electroacupuncture on Rats at 24h
Organism Rattus norvegicus
GSM Sample info Characteristics Value
GSM542196 2Hz_HR_24h_DH1 rat time point: 24h strain: Sprague-Dawley electroacupuncture frequency: 2Hz group: high responder (HR) rats tissue type: dorsal horn (DH); strain: Sprague-Dawley reference: rats sacrificed after stayed in their home cages without receiving electroacupuncture stimulation tissue type: dorsal horn (DH) 1.271336035
GSM542197 2Hz_HR_24h_DH2 rat time point: 24h strain: Sprague-Dawley electroacupuncture frequency: 2Hz group: high responder (HR) rats tissue type: dorsal horn (DH); strain: Sprague-Dawley reference: rats sacrificed after stayed in their home cages without receiving electroacupuncture stimulation tissue type: dorsal horn (DH) 0.0
GSM542198 2Hz_HR_24h_DH3 rat time point: 24h strain: Sprague-Dawley electroacupuncture frequency: 2Hz group: high responder (HR) rats tissue type: dorsal horn (DH); strain: Sprague-Dawley reference: rats sacrificed after stayed in their home cages without receiving electroacupuncture stimulation tissue type: dorsal horn (DH) -0.438654302
GSM542199 2Hz_HR_24h_DH4 rat time point: 24h strain: Sprague-Dawley electroacupuncture frequency: 2Hz group: high responder (HR) rats tissue type: dorsal horn (DH); strain: Sprague-Dawley reference: rats sacrificed after stayed in their home cages without receiving electroacupuncture stimulation tissue type: dorsal horn (DH) 0.528400943
GSM542200 2Hz_HR_24h_DH5 rat time point: 24h strain: Sprague-Dawley electroacupuncture frequency: 2Hz group: high responder (HR) rats tissue type: dorsal horn (DH);strain: Sprague-Dawley reference: rats sacrificed after stayed in their home cages without receiving electroacupuncture stimulation tissue type: dorsal horn (DH) -0.410322522
GSM542201 2Hz_LR_24h_DH1 rat time point: 24h strain: Sprague-Dawley electroacupuncture frequency: 2Hz group: low responder (LR) rats tissue type: dorsal horn (DH);strain: Sprague-Dawley reference: rats sacrificed after stayed in their home cages without receiving electroacupuncture stimulation tissue type: dorsal horn (DH) 1.007291762
GSM542202 2Hz_LR_24h_DH2 rat time point: 24h strain: Sprague-Dawley electroacupuncture frequency: 2Hz group: low responder (LR) rats tissue type: dorsal horn (DH);strain: Sprague-Dawley reference: rats sacrificed after stayed in their home cages without receiving electroacupuncture stimulation tissue type: dorsal horn (DH) 0.216236432
GSM542203 2Hz_LR_24h_DH3 rat time point: 24h strain: Sprague-Dawley electroacupuncture frequency: 2Hz group: low responder (LR) rats tissue type: dorsal horn (DH);strain: Sprague-Dawley reference: rats sacrificed after stayed in their home cages without receiving electroacupuncture stimulation tissue type: dorsal horn (DH) 0.389589106
GSM542204 2Hz_LR_24h_DH4 rat time point: 24h strain: Sprague-Dawley electroacupuncture frequency: 2Hz group: low responder (LR) rats tissue type: dorsal horn (DH);strain: Sprague-Dawley reference: rats sacrificed after stayed in their home cages without receiving electroacupuncture stimulation tissue type: dorsal horn (DH) 0.59569233
GSM542205 2Hz_LR_24h_DH5 rat time point: 24h strain: Sprague-Dawley electroacupuncture frequency: 2Hz group: low responder (LR) rats tissue type: dorsal horn (DH);strain: Sprague-Dawley reference: rats sacrificed after stayed in their home cages without receiving electroacupuncture stimulation tissue type: dorsal horn (DH) 0.002671591
GSM542206 100Hz_HR_24h_DH1 rat time point: 24h strain: Sprague-Dawley electroacupuncture frequency: 100Hz group: high responder (HR) rats tissue type: dorsal horn (DH);strain: Sprague-Dawley reference: rats sacrificed after stayed in their home cages without receiving electroacupuncture stimulation tissue type: dorsal horn (DH) 0.613285855
GSM542207 100Hz_HR_24h_DH2 rat time point: 24h strain: Sprague-Dawley electroacupuncture frequency: 100Hz group: high responder (HR) rats tissue type: dorsal horn (DH);strain: Sprague-Dawley reference: rats sacrificed after stayed in their home cages without receiving electroacupuncture stimulation tissue type: dorsal horn (DH) -0.767440384
GSM542208 100Hz_HR_24h_DH3 rat time point: 24h strain: Sprague-Dawley electroacupuncture frequency: 100Hz group: high responder (HR) rats tissue type: dorsal horn (DH);strain: Sprague-Dawley reference: rats sacrificed after stayed in their home cages without receiving electroacupuncture stimulation tissue type: dorsal horn (DH) -0.137168016
GSM542209 100Hz_HR_24h_DH4 rat time point: 24h strain: Sprague-Dawley electroacupuncture frequency: 100Hz group: high responder (HR) rats tissue type: dorsal horn (DH);strain: Sprague-Dawley reference: rats sacrificed after stayed in their home cages without receiving electroacupuncture stimulation tissue type: dorsal horn (DH) 1.220592586
GSM542210 100Hz_HR_24h_DH5 rat time point: 24h strain: Sprague-Dawley electroacupuncture frequency: 100Hz group: high responder (HR) rats tissue type: dorsal horn (DH);strain: Sprague-Dawley reference: rats sacrificed after stayed in their home cages without receiving electroacupuncture stimulation tissue type: dorsal horn (DH) 0.0
GSM542211 100Hz_LR_24h_DH1 rat time point: 24h strain: Sprague-Dawley electroacupuncture frequency: 100Hz group: low responder (LR) rats tissue type: dorsal horn (DH);strain: Sprague-Dawley reference: rats sacrificed after stayed in their home cages without receiving electroacupuncture stimulation tissue type: dorsal horn (DH) 0.0
GSM542212 100Hz_LR_24h_DH2 rat time point: 24h strain: Sprague-Dawley electroacupuncture frequency: 100Hz group: low responder (LR) rats tissue type: dorsal horn (DH);strain: Sprague-Dawley reference: rats sacrificed after stayed in their home cages without receiving electroacupuncture stimulation tissue type: dorsal horn (DH) 0.0
GSM542213 100Hz_LR_24h_DH3 rat time point: 24h strain: Sprague-Dawley electroacupuncture frequency: 100Hz group: low responder (LR) rats tissue type: dorsal horn (DH);strain: Sprague-Dawley reference: rats sacrificed after stayed in their home cages without receiving electroacupuncture stimulation tissue type: dorsal horn (DH) -0.589461112
GSM542214 100Hz_LR_24h_DH4 rat time point: 24h strain: Sprague-Dawley electroacupuncture frequency: 100Hz group: low responder (LR) rats tissue type: dorsal horn (DH);strain: Sprague-Dawley reference: rats sacrificed after stayed in their home cages without receiving electroacupuncture stimulation tissue type: dorsal horn (DH) 0.0
GSM542215 100Hz_LR_24h_DH5 rat time point: 24h strain: Sprague-Dawley electroacupuncture frequency: 100Hz group: low responder (LR) rats tissue type: dorsal horn (DH);strain: Sprague-Dawley reference: rats sacrificed after stayed in their home cages without receiving electroacupuncture stimulation tissue type: dorsal horn (DH) 0.0

ID GSE244436
Title Similarity and dissimilarity in alteration of gene expression profile associated with inhalational anesthesia between sevoflurane and desflurane
Organism Rattus norvegicus
GSM Sample info Characteristics Value
GSM7816143 Liver, Control for SevoAnes tissue: liver genotype: wild type treatment: Control for SevoAnes 0.420477
GSM7816144 Liver, Anesthetized with sevoflurane for 6 h tissue: liver genotype: wild type treatment: Anesthetized with sevoflurane for 6 h 0.239101
GSM7816145 Liver, Control for DesAnes tissue: liver genotype: wild type treatment: Control for DesAnes 1.356148
GSM7816146 Liver, Anesthetized with desflurane for 6 h tissue: liver genotype: wild type treatment: Anesthetized with desflurane for 6 h 0.241607

ID GSE30365
Title Transcript Profiling of Arcuate Nucleus in Response to Electroacupuncture on Rats
Organism Rattus norvegicus
GSM Sample info Characteristics Value
GSM753495 2Hz_HR_Arc1 rat strain: Sprague-Dawley electroacupuncture: 2Hz responder: high;strain: Sprague-Dawley sample type: control -0.2425
GSM753496 2Hz_HR_Arc2 rat strain: Sprague-Dawley electroacupuncture: 2Hz responder: high;strain: Sprague-Dawley sample type: control -0.6248
GSM753497 2Hz_HR_Arc3 rat strain: Sprague-Dawley electroacupuncture: 2Hz responder: high;strain: Sprague-Dawley sample type: control -0.5271
GSM753498 2Hz_NR_Arc1 rat strain: Sprague-Dawley electroacupuncture: 2Hz responder: no; strain: Sprague-Dawley sample type: control -0.6608
GSM753499 2Hz_NR_Arc2 rat strain: Sprague-Dawley electroacupuncture: 2Hz responder: no; strain: Sprague-Dawley sample type: control -1.5612
GSM753500 2Hz_NR_Arc3 rat strain: Sprague-Dawley electroacupuncture: 2Hz responder: no; strain: Sprague-Dawley sample type: control -0.5646
GSM753501 100Hz_HR_Arc1 rat strain: Sprague-Dawley electroacupuncture: 100Hz responder: high;strain: Sprague-Dawley sample type: control -0.5965
GSM753502 100Hz_HR_Arc2 rat strain: Sprague-Dawley electroacupuncture: 100Hz responder: high;strain: Sprague-Dawley sample type: control -0.8726
GSM753503 100Hz_HR_Arc3 rat strain: Sprague-Dawley electroacupuncture: 100Hz responder: high;strain: Sprague-Dawley sample type: control -0.3528
GSM753504 100Hz_NR_Arc1 rat strain: Sprague-Dawley electroacupuncture: 100Hz responder: no;strain: Sprague-Dawley sample type: control -0.4049
GSM753505 100Hz_NR_Arc2 rat strain: Sprague-Dawley electroacupuncture: 100Hz responder: no;strain: Sprague-Dawley sample type: control -0.7858
GSM753506 100Hz_NR_Arc3 rat strain: Sprague-Dawley electroacupuncture: 100Hz responder: no;strain: Sprague-Dawley sample type: control -0.107

ID GSE53897
Title Genome-wide analysis of dorsal root ganglion (DRG) gene expression after morphine or oxycodone treatment
Organism Rattus norvegicus
GSM Sample info Characteristics Value
GSM1303240 DRG RVM1 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 5.792479
GSM1303241 DRG RVM2 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 5.884618
GSM1303242 DRG RVM3 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 5.69576
GSM1303243 DRG RVM7 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 5.547775
GSM1303244 DRG RVOx2 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 5.621791
GSM1303245 DRG RVOx3 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 5.792118
GSM1303246 DRG RVOx5 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 5.750967
GSM1303247 DRG RVOx7 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 5.759656
GSM1303248 DRG RVS4 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 5.760243
GSM1303249 DRG RVS5 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 5.749729
GSM1303250 DRG RVS6 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 5.704087
GSM1303251 DRG RVS7 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 5.751841
GSM1303252 DRG RSM1 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 5.702839
GSM1303253 DRG RSM2 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 5.775874
GSM1303254 DRG RSM4 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 5.765546
GSM1303255 DRG RSM5 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 5.661159
GSM1303256 DRG RSOx1 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 5.703164
GSM1303257 DRG RSOx2 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 5.791825
GSM1303258 DRG RSOx3 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 5.71474
GSM1303259 DRG RSOx4 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 5.825866
GSM1303260 DRG RSS1 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 5.708069
GSM1303261 DRG RSS2 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 5.804952
GSM1303262 DRG RSS3 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 5.696683
GSM1303263 DRG RSS6 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 5.84414

ID GSE55573
Title Using DNA microarray to screen intracellular signal pathways of hypoglycemic activity by electroacupuncture of Zusanli (ST36) acupoints in streptozotocin-induced rats with diabetes
Organism Rattus norvegicus
GSM Sample info Characteristics Value
GSM1339443 Mock skeletal muscle strain: Wistar age: 8-10 week-old gender: Male 114.3645
GSM1339444 EA (electroacupuncture) skeletal muscle strain: Wistar age: 8-10 week-old gender: Male 114.7674

ID GSE58803
Title Transcript Profiling of Periaqueductal Gray in Response to Electroacupuncture on Rats
Organism Rattus norvegicus
GSM Sample info Characteristics Value
GSM1419812 2Hz_HR_1h_PAG1 rat strain: Sprague-Dawley tissue: PAG treatment: 2Hz electroacupuncture responder type: high responder(HR) time: 1h;strain: Sprague-Dawley treatment: control tissue: PAG -0.625840401
GSM1419813 2Hz_HR_1h_PAG2 rat strain: Sprague-Dawley tissue: PAG treatment: 2Hz electroacupuncture responder type: high responder(HR) time: 1h;strain: Sprague-Dawley treatment: control tissue: PAG 0.0
GSM1419814 2Hz_HR_1h_PAG3 rat strain: Sprague-Dawley tissue: PAG treatment: 2Hz electroacupuncture responder type: high responder(HR) time: 1h; strain: Sprague-Dawley treatment: control tissue: PAG -0.360963627
GSM1419815 2Hz_HR_1h_PAG4 rat strain: Sprague-Dawley tissue: PAG treatment: 2Hz electroacupuncture responder type: high responder(HR) time: 1h;strain: Sprague-Dawley treatment: control tissue: PAG -0.974763488
GSM1419816 2Hz_HR_1h_PAG5 rat strain: Sprague-Dawley tissue: PAG treatment: 2Hz electroacupuncture responder type: high responder(HR) time: 1h;strain: Sprague-Dawley treatment: control tissue: PAG -0.843130293
GSM1419817 2Hz_NR_1h_PAG1 rat strain: Sprague-Dawley tissue: PAG treatment: 2Hz electroacupuncture responder type: low responder(NR) time: 1h;strain: Sprague-Dawley treatment: control tissue: PAG 0.0
GSM1419818 2Hz_NR_1h_PAG2 rat strain: Sprague-Dawley tissue: PAG treatment: 2Hz electroacupuncture responder type: low responder(NR) time: 1h;strain: Sprague-Dawley treatment: control tissue: PAG 0.357410428
GSM1419819 2Hz_NR_1h_PAG3 rat strain: Sprague-Dawley tissue: PAG treatment: 2Hz electroacupuncture responder type: low responder(NR) time: 1h;strain: Sprague-Dawley treatment: control tissue: PAG -0.162504778
GSM1419820 2Hz_NR_1h_PAG4 rat strain: Sprague-Dawley tissue: PAG treatment: 2Hz electroacupuncture responder type: low responder(NR) time: 1h;strain: Sprague-Dawley treatment: control tissue: PAG -0.480832255
GSM1419821 100Hz_HR_1h_PAG1 rat strain: Sprague-Dawley tissue: PAG treatment: 100Hz electroacupuncture responder type: high responder(HR) time: 1h;strain: Sprague-Dawley treatment: control tissue: PAG 0.0
GSM1419822 100Hz_HR_1h_PAG2 rat strain: Sprague-Dawley tissue: PAG treatment: 100Hz electroacupuncture responder type: high responder(HR) time: 1h;strain: Sprague-Dawley treatment: control tissue: PAG 2.259204053
GSM1419823 100Hz_HR_1h_PAG3 rat strain: Sprague-Dawley tissue: PAG treatment: 100Hz electroacupuncture responder type: high responder(HR) time: 1h;strain: Sprague-Dawley treatment: control tissue: PAG 0.0
GSM1419824 100Hz_HR_1h_PAG4 rat strain: Sprague-Dawley tissue: PAG treatment: 100Hz electroacupuncture responder type: high responder(HR) time: 1h;strain: Sprague-Dawley treatment: control tissue: PAG 2.860881389
GSM1419825 100Hz_HR_1h_PAG5 rat strain: Sprague-Dawley tissue: PAG treatment: 100Hz electroacupuncture responder type: high responder(HR) time: 1h;strain: Sprague-Dawley treatment: control tissue: PAG 0.0
GSM1419826 100Hz_NR_1h_PAG1 rat strain: Sprague-Dawley tissue: PAG treatment: 100Hz electroacupuncture responder type: low responder(NR) time: 1h; strain: Sprague-Dawley treatment: control tissue: PAG 0.0
GSM1419827 100Hz_NR_1h_PAG2 rat strain: Sprague-Dawley tissue: PAG treatment: 100Hz electroacupuncture responder type: low responder(NR) time: 1h; strain: Sprague-Dawley treatment: control tissue: PAG 0.0
GSM1419828 100Hz_NR_1h_PAG3 rat strain: Sprague-Dawley tissue: PAG treatment: 100Hz electroacupuncture responder type: low responder(NR) time: 1h; strain: Sprague-Dawley treatment: control tissue: PAG 0.0
GSM1419829 100Hz_NR_1h_PAG4 rat strain: Sprague-Dawley tissue: PAG treatment: 100Hz electroacupuncture responder type: low responder(NR) time: 1h;strain: Sprague-Dawley treatment: control tissue: PAG 0.0
GSM1419830 100Hz_NR_1h_PAG5 rat strain: Sprague-Dawley tissue: PAG treatment: 100Hz electroacupuncture responder type: low responder(NR) time: 1h;strain: Sprague-Dawley treatment: control tissue: PAG 0.0
GSM1419831 2Hz_HR_24h_PAG1 rat strain: Sprague-Dawley tissue: PAG treatment: 2Hz electroacupuncture responder type: high responder(HR) time: 24h;strain: Sprague-Dawley treatment: control tissue: PAG 0.413416254
GSM1419832 2Hz_HR_24h_PAG2 rat strain: Sprague-Dawley tissue: PAG treatment: 2Hz electroacupuncture responder type: high responder(HR) time: 24h;strain: Sprague-Dawley treatment: control tissue: PAG -0.109865837
GSM1419833 2Hz_HR_24h_PAG3 rat strain: Sprague-Dawley tissue: PAG treatment: 2Hz electroacupuncture responder type: high responder(HR) time: 24h; strain: Sprague-Dawley treatment: control tissue: PAG -0.553197165
GSM1419834 2Hz_HR_24h_PAG4 rat strain: Sprague-Dawley tissue: PAG treatment: 2Hz electroacupuncture responder type: high responder(HR) time: 24h;strain: Sprague-Dawley treatment: control tissue: PAG -0.645722329
GSM1419835 2Hz_HR_24h_PAG5 rat strain: Sprague-Dawley tissue: PAG treatment: 2Hz electroacupuncture responder type: high responder(HR) time: 24h;strain: Sprague-Dawley treatment: control tissue: PAG -0.514607037
GSM1419836 2Hz_NR_24h_PAG1 rat strain: Sprague-Dawley tissue: PAG treatment: 2Hz electroacupuncture responder type: low responder(NR) time: 24h;strain: Sprague-Dawley treatment: control tissue: PAG -0.217743179
GSM1419837 2Hz_NR_24h_PAG2 rat strain: Sprague-Dawley tissue: PAG treatment: 2Hz electroacupuncture responder type: low responder(NR) time: 24h;strain: Sprague-Dawley treatment: control tissue: PAG 0.599534497
GSM1419838 2Hz_NR_24h_PAG3 rat strain: Sprague-Dawley tissue: PAG treatment: 2Hz electroacupuncture responder type: low responder(NR) time: 24h;strain: Sprague-Dawley treatment: control tissue: PAG 2.315314508
GSM1419839 2Hz_NR_24h_PAG4 rat strain: Sprague-Dawley tissue: PAG treatment: 2Hz electroacupuncture responder type: low responder(NR) time: 24h;strain: Sprague-Dawley treatment: control tissue: PAG -0.423519134
GSM1419840 2Hz_NR_24h_PAG5 rat strain: Sprague-Dawley tissue: PAG treatment: 2Hz electroacupuncture responder type: low responder(NR) time: 24h;strain: Sprague-Dawley treatment: control tissue: PAG -0.41456918
GSM1419841 100Hz_HR_24h_PAG1 rat strain: Sprague-Dawley tissue: PAG treatment: 100Hz electroacupuncture responder type: high responder(HR) time: 24h;strain: Sprague-Dawley treatment: control tissue: PAG 0.045965352
GSM1419842 100Hz_HR_24h_PAG2 rat strain: Sprague-Dawley tissue: PAG treatment: 100Hz electroacupuncture responder type: high responder(HR) time: 24h;strain: Sprague-Dawley treatment: control tissue: PAG -1.187642759
GSM1419843 100Hz_HR_24h_PAG3 rat strain: Sprague-Dawley tissue: PAG treatment: 100Hz electroacupuncture responder type: high responder(HR) time: 24h;strain: Sprague-Dawley treatment: control tissue: PAG -0.659681893
GSM1419844 100Hz_HR_24h_PAG4 rat strain: Sprague-Dawley tissue: PAG treatment: 100Hz electroacupuncture responder type: high responder(HR) time: 24h;strain: Sprague-Dawley treatment: control tissue: PAG 0.178202664
GSM1419845 100Hz_HR_24h_PAG5 rat strain: Sprague-Dawley tissue: PAG treatment: 100Hz electroacupuncture responder type: high responder(HR) time: 24h;strain: Sprague-Dawley treatment: control tissue: PAG 0.0
GSM1419846 100Hz_NR_24h_PAG1 rat strain: Sprague-Dawley tissue: PAG treatment: 100Hz electroacupuncture responder type: low responder(NR) time: 24h;strain: Sprague-Dawley treatment: control tissue: PAG -0.943859684
GSM1419847 100Hz_NR_24h_PAG2 rat strain: Sprague-Dawley tissue: PAG treatment: 100Hz electroacupuncture responder type: low responder(NR) time: 24h;strain: Sprague-Dawley treatment: control tissue: PAG 4.516064853
GSM1419848 100Hz_NR_24h_PAG3 rat strain: Sprague-Dawley tissue: PAG treatment: 100Hz electroacupuncture responder type: low responder(NR) time: 24h;strain: Sprague-Dawley treatment: control tissue: PAG -0.999261617
GSM1419849 100Hz_NR_24h_PAG4 rat strain: Sprague-Dawley tissue: PAG treatment: 100Hz electroacupuncture responder type: low responder(NR) time: 24h;strain: Sprague-Dawley treatment: control tissue: PAG 0.0
GSM1419850 100Hz_NR_24h_PAG5 rat strain: Sprague-Dawley tissue: PAG treatment: 100Hz electroacupuncture responder type: low responder(NR) time: 24h;strain: Sprague-Dawley treatment: control tissue: PAG -0.744561758