Gene symbol: Tlr4

Organism: Rattus norvegicus

Summary: Enables lipopolysaccharide binding activity and phosphatidylinositol 3-kinase binding activity. Involved in several processes, including detection of stimulus involved in sensory perception of pain; immune response-regulating signaling pathway; and response to steroid hormone. Located in cell surface and cytoplasm. Colocalizes with membrane raft. Used to study several diseases, including carotid stenosis; ileitis; neuropathy (multiple); obesity; and renal fibrosis. Biomarker of several diseases, including kidney failure (multiple); pancreatitis (multiple); perinatal necrotizing enterocolitis; pulpitis; and sciatic neuropathy. Human ortholog(s) of this gene implicated in several diseases, including allergic contact dermatitis (multiple); artery disease (multiple); autoimmune disease (multiple); eye disease (multiple); and lung disease (multiple). Orthologous to human TLR4 (toll like receptor 4). [provided by Alliance of Genome Resources, Apr 2022]

NCBI gene ID: 29260 Ensembl:ENSRNOG00000010522 AllianceGenome:RGD:3870


GO Annotation


Category Term ID Term description
Process GO:0000165 MAPK cascade
Process GO:0001666 Response to hypoxia
Process GO:0001774 Microglial cell activation
Process GO:0001775 Cell activation
Process GO:0001817 Regulation of cytokine production
Process GO:0001818 Negative regulation of cytokine production
Process GO:0001819 Positive regulation of cytokine production
Process GO:0001894 Tissue homeostasis
Process GO:0001932 Regulation of protein phosphorylation
Process GO:0001934 Positive regulation of protein phosphorylation
Process GO:0002218 Activation of innate immune response
Process GO:0002221 Pattern recognition receptor signaling pathway
Process GO:0002224 Toll-like receptor signaling pathway
Process GO:0002237 Response to molecule of bacterial origin
Process GO:0002246 Wound healing involved in inflammatory response
Process GO:0002250 Adaptive immune response
Process GO:0002252 Immune effector process
Process GO:0002253 Activation of immune response
Process GO:0002263 Cell activation involved in immune response
Process GO:0002269 Leukocyte activation involved in inflammatory response
Process GO:0002274 Myeloid leukocyte activation
Process GO:0002285 Lymphocyte activation involved in immune response
Process GO:0002312 B cell activation involved in immune response
Process GO:0002322 B cell proliferation involved in immune response
Process GO:0002366 Leukocyte activation involved in immune response
Process GO:0002376 Immune system process
Process GO:0002443 Leukocyte mediated immunity
Process GO:0002449 Lymphocyte mediated immunity
Process GO:0002460 Adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
Process GO:0002532 Production of molecular mediator involved in inflammatory response
Process GO:0002537 Nitric oxide production involved in inflammatory response
Process GO:0002682 Regulation of immune system process
Process GO:0002684 Positive regulation of immune system process
Process GO:0002694 Regulation of leukocyte activation
Process GO:0002696 Positive regulation of leukocyte activation
Process GO:0002697 Regulation of immune effector process
Process GO:0002699 Positive regulation of immune effector process
Process GO:0002700 Regulation of production of molecular mediator of immune response
Process GO:0002702 Positive regulation of production of molecular mediator of immune response
Process GO:0002703 Regulation of leukocyte mediated immunity
Process GO:0002718 Regulation of cytokine production involved in immune response
Process GO:0002720 Positive regulation of cytokine production involved in immune response
Process GO:0002730 Regulation of dendritic cell cytokine production
Process GO:0002753 Cytoplasmic pattern recognition receptor signaling pathway
Process GO:0002755 MyD88-dependent toll-like receptor signaling pathway
Process GO:0002756 MyD88-independent toll-like receptor signaling pathway
Process GO:0002757 Immune response-activating signal transduction
Process GO:0002758 Innate immune response-activating signal transduction
Process GO:0002764 Immune response-regulating signaling pathway
Process GO:0002831 Regulation of response to biotic stimulus
Process GO:0002833 Positive regulation of response to biotic stimulus
Process GO:0003008 System process
Process GO:0003009 Skeletal muscle contraction
Process GO:0003012 Muscle system process
Process GO:0006082 Organic acid metabolic process
Process GO:0006355 Regulation of transcription, DNA-templated
Process GO:0006357 Regulation of transcription by RNA polymerase II
Process GO:0006468 Protein phosphorylation
Process GO:0006690 Icosanoid metabolic process
Process GO:0006691 Leukotriene metabolic process
Process GO:0006793 Phosphorus metabolic process
Process GO:0006796 Phosphate-containing compound metabolic process
Process GO:0006807 Nitrogen compound metabolic process
Process GO:0006809 Nitric oxide biosynthetic process
Process GO:0006810 Transport
Process GO:0006909 Phagocytosis
Process GO:0006936 Muscle contraction
Process GO:0006941 Striated muscle contraction
Process GO:0006950 Response to stress
Process GO:0006952 Defense response
Process GO:0006954 Inflammatory response
Process GO:0006955 Immune response
Process GO:0006979 Response to oxidative stress
Process GO:0007154 Cell communication
Process GO:0007165 Signal transduction
Process GO:0007166 Cell surface receptor signaling pathway
Process GO:0007249 I-kappaB kinase/NF-kappaB signaling
Process GO:0007252 I-kappaB phosphorylation
Process GO:0007254 JNK cascade
Process GO:0007275 Multicellular organism development
Process GO:0007399 Nervous system development
Process GO:0007417 Central nervous system development
Process GO:0007586 Digestion
Process GO:0007600 Sensory perception
Process GO:0008152 Metabolic process
Process GO:0008283 Cell population proliferation
Process GO:0008284 Positive regulation of cell population proliferation
Process GO:0009058 Biosynthetic process
Process GO:0009059 Macromolecule biosynthetic process
Process GO:0009266 Response to temperature stimulus
Process GO:0009581 Detection of external stimulus
Process GO:0009582 Detection of abiotic stimulus
Process GO:0009593 Detection of chemical stimulus
Process GO:0009595 Detection of biotic stimulus
Process GO:0009605 Response to external stimulus
Process GO:0009607 Response to biotic stimulus
Process GO:0009611 Response to wounding
Process GO:0009612 Response to mechanical stimulus
Process GO:0009617 Response to bacterium
Process GO:0009628 Response to abiotic stimulus
Process GO:0009636 Response to toxic substance
Process GO:0009719 Response to endogenous stimulus
Process GO:0009725 Response to hormone
Process GO:0009889 Regulation of biosynthetic process
Process GO:0009891 Positive regulation of biosynthetic process
Process GO:0009892 Negative regulation of metabolic process
Process GO:0009893 Positive regulation of metabolic process
Process GO:0009966 Regulation of signal transduction
Process GO:0009967 Positive regulation of signal transduction
Process GO:0009968 Negative regulation of signal transduction
Process GO:0009987 Cellular process
Process GO:0010001 Glial cell differentiation
Process GO:0010033 Response to organic substance
Process GO:0010243 Response to organonitrogen compound
Process GO:0010468 Regulation of gene expression
Process GO:0010543 Regulation of platelet activation
Process GO:0010556 Regulation of macromolecule biosynthetic process
Process GO:0010557 Positive regulation of macromolecule biosynthetic process
Process GO:0010562 Positive regulation of phosphorus metabolic process
Process GO:0010572 Positive regulation of platelet activation
Process GO:0010604 Positive regulation of macromolecule metabolic process
Process GO:0010605 Negative regulation of macromolecule metabolic process
Process GO:0010628 Positive regulation of gene expression
Process GO:0010629 Negative regulation of gene expression
Process GO:0010646 Regulation of cell communication
Process GO:0010647 Positive regulation of cell communication
Process GO:0010648 Negative regulation of cell communication
Process GO:0010669 Epithelial structure maintenance
Process GO:0010935 Regulation of macrophage cytokine production
Process GO:0010941 Regulation of cell death
Process GO:0010942 Positive regulation of cell death
Process GO:0014002 Astrocyte development
Process GO:0014070 Response to organic cyclic compound
Process GO:0014072 Response to isoquinoline alkaloid
Process GO:0014823 Response to activity
Process GO:0014910 Regulation of smooth muscle cell migration
Process GO:0014911 Positive regulation of smooth muscle cell migration
Process GO:0016048 Detection of temperature stimulus
Process GO:0016064 Immunoglobulin mediated immune response
Process GO:0016192 Vesicle-mediated transport
Process GO:0016310 Phosphorylation
Process GO:0019219 Regulation of nucleobase-containing compound metabolic process
Process GO:0019220 Regulation of phosphate metabolic process
Process GO:0019222 Regulation of metabolic process
Process GO:0019233 Sensory perception of pain
Process GO:0019538 Protein metabolic process
Process GO:0019724 B cell mediated immunity
Process GO:0019752 Carboxylic acid metabolic process
Process GO:0021782 Glial cell development
Process GO:0022008 Neurogenesis
Process GO:0022600 Digestive system process
Process GO:0023051 Regulation of signaling
Process GO:0023052 Signaling
Process GO:0023056 Positive regulation of signaling
Process GO:0023057 Negative regulation of signaling
Process GO:0030154 Cell differentiation
Process GO:0030277 Maintenance of gastrointestinal epithelium
Process GO:0030334 Regulation of cell migration
Process GO:0030335 Positive regulation of cell migration
Process GO:0030522 Intracellular receptor signaling pathway
Process GO:0030888 Regulation of B cell proliferation
Process GO:0030890 Positive regulation of B cell proliferation
Process GO:0031098 Stress-activated protein kinase signaling cascade
Process GO:0031323 Regulation of cellular metabolic process
Process GO:0031325 Positive regulation of cellular metabolic process
Process GO:0031326 Regulation of cellular biosynthetic process
Process GO:0031328 Positive regulation of cellular biosynthetic process
Process GO:0031334 Positive regulation of protein-containing complex assembly
Process GO:0031347 Regulation of defense response
Process GO:0031349 Positive regulation of defense response
Process GO:0031399 Regulation of protein modification process
Process GO:0031401 Positive regulation of protein modification process
Process GO:0031644 Regulation of nervous system process
Process GO:0031663 Lipopolysaccharide-mediated signaling pathway
Process GO:0031960 Response to corticosteroid
Process GO:0032101 Regulation of response to external stimulus
Process GO:0032103 Positive regulation of response to external stimulus
Process GO:0032479 Regulation of type I interferon production
Process GO:0032481 Positive regulation of type I interferon production
Process GO:0032490 Detection of molecule of bacterial origin
Process GO:0032496 Response to lipopolysaccharide
Process GO:0032497 Detection of lipopolysaccharide
Process GO:0032501 Multicellular organismal process
Process GO:0032502 Developmental process
Process GO:0032526 Response to retinoic acid
Process GO:0032570 Response to progesterone
Process GO:0032642 Regulation of chemokine production
Process GO:0032647 Regulation of interferon-alpha production
Process GO:0032648 Regulation of interferon-beta production
Process GO:0032649 Regulation of interferon-gamma production
Process GO:0032651 Regulation of interleukin-1 beta production
Process GO:0032652 Regulation of interleukin-1 production
Process GO:0032653 Regulation of interleukin-10 production
Process GO:0032655 Regulation of interleukin-12 production
Process GO:0032660 Regulation of interleukin-17 production
Process GO:0032667 Regulation of interleukin-23 production
Process GO:0032675 Regulation of interleukin-6 production
Process GO:0032677 Regulation of interleukin-8 production
Process GO:0032680 Regulation of tumor necrosis factor production
Process GO:0032689 Negative regulation of interferon-gamma production
Process GO:0032700 Negative regulation of interleukin-17 production
Process GO:0032707 Negative regulation of interleukin-23 production
Process GO:0032715 Negative regulation of interleukin-6 production
Process GO:0032720 Negative regulation of tumor necrosis factor production
Process GO:0032722 Positive regulation of chemokine production
Process GO:0032727 Positive regulation of interferon-alpha production
Process GO:0032728 Positive regulation of interferon-beta production
Process GO:0032729 Positive regulation of interferon-gamma production
Process GO:0032731 Positive regulation of interleukin-1 beta production
Process GO:0032732 Positive regulation of interleukin-1 production
Process GO:0032733 Positive regulation of interleukin-10 production
Process GO:0032735 Positive regulation of interleukin-12 production
Process GO:0032755 Positive regulation of interleukin-6 production
Process GO:0032757 Positive regulation of interleukin-8 production
Process GO:0032760 Positive regulation of tumor necrosis factor production
Process GO:0032868 Response to insulin
Process GO:0032872 Regulation of stress-activated MAPK cascade
Process GO:0032874 Positive regulation of stress-activated MAPK cascade
Process GO:0032879 Regulation of localization
Process GO:0032880 Regulation of protein localization
Process GO:0032943 Mononuclear cell proliferation
Process GO:0032944 Regulation of mononuclear cell proliferation
Process GO:0032946 Positive regulation of mononuclear cell proliferation
Process GO:0033554 Cellular response to stress
Process GO:0033674 Positive regulation of kinase activity
Process GO:0033993 Response to lipid
Process GO:0034097 Response to cytokine
Process GO:0034142 Toll-like receptor 4 signaling pathway
Process GO:0034341 Response to interferon-gamma
Process GO:0034641 Cellular nitrogen compound metabolic process
Process GO:0035556 Intracellular signal transduction
Process GO:0035666 TRIF-dependent toll-like receptor signaling pathway
Process GO:0035872 Nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway
Process GO:0036119 Response to platelet-derived growth factor
Process GO:0036120 Cellular response to platelet-derived growth factor stimulus
Process GO:0036211 Protein modification process
Process GO:0036293 Response to decreased oxygen levels
Process GO:0040012 Regulation of locomotion
Process GO:0040017 Positive regulation of locomotion
Process GO:0042060 Wound healing
Process GO:0042063 Gliogenesis
Process GO:0042100 B cell proliferation
Process GO:0042113 B cell activation
Process GO:0042116 Macrophage activation
Process GO:0042127 Regulation of cell population proliferation
Process GO:0042221 Response to chemical
Process GO:0042325 Regulation of phosphorylation
Process GO:0042327 Positive regulation of phosphorylation
Process GO:0042592 Homeostatic process
Process GO:0042742 Defense response to bacterium
Process GO:0042981 Regulation of apoptotic process
Process GO:0043030 Regulation of macrophage activation
Process GO:0043032 Positive regulation of macrophage activation
Process GO:0043065 Positive regulation of apoptotic process
Process GO:0043067 Regulation of programmed cell death
Process GO:0043068 Positive regulation of programmed cell death
Process GO:0043085 Positive regulation of catalytic activity
Process GO:0043122 Regulation of I-kappaB kinase/NF-kappaB signaling
Process GO:0043123 Positive regulation of I-kappaB kinase/NF-kappaB signaling
Process GO:0043170 Macromolecule metabolic process
Process GO:0043207 Response to external biotic stimulus
Process GO:0043254 Regulation of protein-containing complex assembly
Process GO:0043278 Response to morphine
Process GO:0043279 Response to alkaloid
Process GO:0043388 Positive regulation of DNA binding
Process GO:0043405 Regulation of MAP kinase activity
Process GO:0043406 Positive regulation of MAP kinase activity
Process GO:0043408 Regulation of MAPK cascade
Process GO:0043409 Negative regulation of MAPK cascade
Process GO:0043410 Positive regulation of MAPK cascade
Process GO:0043412 Macromolecule modification
Process GO:0043434 Response to peptide hormone
Process GO:0043436 Oxoacid metabolic process
Process GO:0043549 Regulation of kinase activity
Process GO:0044057 Regulation of system process
Process GO:0044087 Regulation of cellular component biogenesis
Process GO:0044089 Positive regulation of cellular component biogenesis
Process GO:0044093 Positive regulation of molecular function
Process GO:0044237 Cellular metabolic process
Process GO:0044238 Primary metabolic process
Process GO:0044249 Cellular biosynthetic process
Process GO:0044271 Cellular nitrogen compound biosynthetic process
Process GO:0044281 Small molecule metabolic process
Process GO:0044419 Biological process involved in interspecies interaction between organisms
Process GO:0045087 Innate immune response
Process GO:0045088 Regulation of innate immune response
Process GO:0045089 Positive regulation of innate immune response
Process GO:0045321 Leukocyte activation
Process GO:0045342 MHC class II biosynthetic process
Process GO:0045346 Regulation of MHC class II biosynthetic process
Process GO:0045348 Positive regulation of MHC class II biosynthetic process
Process GO:0045428 Regulation of nitric oxide biosynthetic process
Process GO:0045429 Positive regulation of nitric oxide biosynthetic process
Process GO:0045471 Response to ethanol
Process GO:0045859 Regulation of protein kinase activity
Process GO:0045860 Positive regulation of protein kinase activity
Process GO:0045893 Positive regulation of transcription, DNA-templated
Process GO:0045935 Positive regulation of nucleobase-containing compound metabolic process
Process GO:0045937 Positive regulation of phosphate metabolic process
Process GO:0045944 Positive regulation of transcription by RNA polymerase II
Process GO:0046209 Nitric oxide metabolic process
Process GO:0046328 Regulation of JNK cascade
Process GO:0046330 Positive regulation of JNK cascade
Process GO:0046649 Lymphocyte activation
Process GO:0046651 Lymphocyte proliferation
Process GO:0048468 Cell development
Process GO:0048518 Positive regulation of biological process
Process GO:0048519 Negative regulation of biological process
Process GO:0048522 Positive regulation of cellular process
Process GO:0048523 Negative regulation of cellular process
Process GO:0048545 Response to steroid hormone
Process GO:0048583 Regulation of response to stimulus
Process GO:0048584 Positive regulation of response to stimulus
Process GO:0048585 Negative regulation of response to stimulus
Process GO:0048660 Regulation of smooth muscle cell proliferation
Process GO:0048661 Positive regulation of smooth muscle cell proliferation
Process GO:0048708 Astrocyte differentiation
Process GO:0048731 System development
Process GO:0048856 Anatomical structure development
Process GO:0048869 Cellular developmental process
Process GO:0048871 Multicellular organismal homeostasis
Process GO:0050670 Regulation of lymphocyte proliferation
Process GO:0050671 Positive regulation of lymphocyte proliferation
Process GO:0050708 Regulation of protein secretion
Process GO:0050714 Positive regulation of protein secretion
Process GO:0050727 Regulation of inflammatory response
Process GO:0050729 Positive regulation of inflammatory response
Process GO:0050730 Regulation of peptidyl-tyrosine phosphorylation
Process GO:0050731 Positive regulation of peptidyl-tyrosine phosphorylation
Process GO:0050776 Regulation of immune response
Process GO:0050778 Positive regulation of immune response
Process GO:0050789 Regulation of biological process
Process GO:0050790 Regulation of catalytic activity
Process GO:0050794 Regulation of cellular process
Process GO:0050829 Defense response to Gram-negative bacterium
Process GO:0050864 Regulation of B cell activation
Process GO:0050865 Regulation of cell activation
Process GO:0050867 Positive regulation of cell activation
Process GO:0050871 Positive regulation of B cell activation
Process GO:0050877 Nervous system process
Process GO:0050879 Multicellular organismal movement
Process GO:0050881 Musculoskeletal movement
Process GO:0050896 Response to stimulus
Process GO:0050905 Neuromuscular process
Process GO:0050906 Detection of stimulus involved in sensory perception
Process GO:0050951 Sensory perception of temperature stimulus
Process GO:0050954 Sensory perception of mechanical stimulus
Process GO:0050961 Detection of temperature stimulus involved in sensory perception
Process GO:0050965 Detection of temperature stimulus involved in sensory perception of pain
Process GO:0050966 Detection of mechanical stimulus involved in sensory perception of pain
Process GO:0050974 Detection of mechanical stimulus involved in sensory perception
Process GO:0050982 Detection of mechanical stimulus
Process GO:0051046 Regulation of secretion
Process GO:0051047 Positive regulation of secretion
Process GO:0051049 Regulation of transport
Process GO:0051050 Positive regulation of transport
Process GO:0051090 Regulation of DNA-binding transcription factor activity
Process GO:0051091 Positive regulation of DNA-binding transcription factor activity
Process GO:0051092 Positive regulation of NF-kappaB transcription factor activity
Process GO:0051098 Regulation of binding
Process GO:0051099 Positive regulation of binding
Process GO:0051101 Regulation of DNA binding
Process GO:0051128 Regulation of cellular component organization
Process GO:0051130 Positive regulation of cellular component organization
Process GO:0051171 Regulation of nitrogen compound metabolic process
Process GO:0051173 Positive regulation of nitrogen compound metabolic process
Process GO:0051174 Regulation of phosphorus metabolic process
Process GO:0051179 Localization
Process GO:0051222 Positive regulation of protein transport
Process GO:0051223 Regulation of protein transport
Process GO:0051234 Establishment of localization
Process GO:0051239 Regulation of multicellular organismal process
Process GO:0051240 Positive regulation of multicellular organismal process
Process GO:0051241 Negative regulation of multicellular organismal process
Process GO:0051246 Regulation of protein metabolic process
Process GO:0051247 Positive regulation of protein metabolic process
Process GO:0051249 Regulation of lymphocyte activation
Process GO:0051251 Positive regulation of lymphocyte activation
Process GO:0051252 Regulation of RNA metabolic process
Process GO:0051254 Positive regulation of RNA metabolic process
Process GO:0051338 Regulation of transferase activity
Process GO:0051347 Positive regulation of transferase activity
Process GO:0051384 Response to glucocorticoid
Process GO:0051403 Stress-activated MAPK cascade
Process GO:0051606 Detection of stimulus
Process GO:0051707 Response to other organism
Process GO:0051716 Cellular response to stimulus
Process GO:0051769 Regulation of nitric-oxide synthase biosynthetic process
Process GO:0051770 Positive regulation of nitric-oxide synthase biosynthetic process
Process GO:0051930 Regulation of sensory perception of pain
Process GO:0051931 Regulation of sensory perception
Process GO:0055094 Response to lipoprotein particle
Process GO:0060249 Anatomical structure homeostasis
Process GO:0060255 Regulation of macromolecule metabolic process
Process GO:0060341 Regulation of cellular localization
Process GO:0060729 Intestinal epithelial structure maintenance
Process GO:0060759 Regulation of response to cytokine stimulus
Process GO:0060760 Positive regulation of response to cytokine stimulus
Process GO:0060907 Positive regulation of macrophage cytokine production
Process GO:0061081 Positive regulation of myeloid leukocyte cytokine production involved in immune response
Process GO:0061900 Glial cell activation
Process GO:0062149 Detection of stimulus involved in sensory perception of pain
Process GO:0062207 Regulation of pattern recognition receptor signaling pathway
Process GO:0062208 Positive regulation of pattern recognition receptor signaling pathway
Process GO:0065007 Biological regulation
Process GO:0065008 Regulation of biological quality
Process GO:0065009 Regulation of molecular function
Process GO:0070201 Regulation of establishment of protein localization
Process GO:0070302 Regulation of stress-activated protein kinase signaling cascade
Process GO:0070304 Positive regulation of stress-activated protein kinase signaling cascade
Process GO:0070371 ERK1 and ERK2 cascade
Process GO:0070372 Regulation of ERK1 and ERK2 cascade
Process GO:0070373 Negative regulation of ERK1 and ERK2 cascade
Process GO:0070374 Positive regulation of ERK1 and ERK2 cascade
Process GO:0070391 Response to lipoteichoic acid
Process GO:0070423 Nucleotide-binding oligomerization domain containing signaling pathway
Process GO:0070424 Regulation of nucleotide-binding oligomerization domain containing signaling pathway
Process GO:0070426 Positive regulation of nucleotide-binding oligomerization domain containing signaling pathway
Process GO:0070427 Nucleotide-binding oligomerization domain containing 1 signaling pathway
Process GO:0070428 Regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway
Process GO:0070430 Positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway
Process GO:0070431 Nucleotide-binding oligomerization domain containing 2 signaling pathway
Process GO:0070432 Regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway
Process GO:0070434 Positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway
Process GO:0070482 Response to oxygen levels
Process GO:0070542 Response to fatty acid
Process GO:0070661 Leukocyte proliferation
Process GO:0070663 Regulation of leukocyte proliferation
Process GO:0070665 Positive regulation of leukocyte proliferation
Process GO:0070848 Response to growth factor
Process GO:0070887 Cellular response to chemical stimulus
Process GO:0071214 Cellular response to abiotic stimulus
Process GO:0071216 Cellular response to biotic stimulus
Process GO:0071219 Cellular response to molecule of bacterial origin
Process GO:0071222 Cellular response to lipopolysaccharide
Process GO:0071223 Cellular response to lipoteichoic acid
Process GO:0071260 Cellular response to mechanical stimulus
Process GO:0071300 Cellular response to retinoic acid
Process GO:0071310 Cellular response to organic substance
Process GO:0071345 Cellular response to cytokine stimulus
Process GO:0071346 Cellular response to interferon-gamma
Process GO:0071363 Cellular response to growth factor stimulus
Process GO:0071396 Cellular response to lipid
Process GO:0071402 Cellular response to lipoprotein particle stimulus
Process GO:0071417 Cellular response to organonitrogen compound
Process GO:0071495 Cellular response to endogenous stimulus
Process GO:0071496 Cellular response to external stimulus
Process GO:0071704 Organic substance metabolic process
Process GO:0071900 Regulation of protein serine/threonine kinase activity
Process GO:0071902 Positive regulation of protein serine/threonine kinase activity
Process GO:0080090 Regulation of primary metabolic process
Process GO:0080134 Regulation of response to stress
Process GO:0080135 Regulation of cellular response to stress
Process GO:0080164 Regulation of nitric oxide metabolic process
Process GO:0090594 Inflammatory response to wounding
Process GO:0097305 Response to alcohol
Process GO:0098542 Defense response to other organism
Process GO:0098581 Detection of external biotic stimulus
Process GO:0104004 Cellular response to environmental stimulus
Process GO:0120161 Regulation of cold-induced thermogenesis
Process GO:0120163 Negative regulation of cold-induced thermogenesis
Process GO:0140052 Cellular response to oxidised low-density lipoprotein particle stimulus
Process GO:0150076 Neuroinflammatory response
Process GO:1900015 Regulation of cytokine production involved in inflammatory response
Process GO:1900017 Positive regulation of cytokine production involved in inflammatory response
Process GO:1900225 Regulation of NLRP3 inflammasome complex assembly
Process GO:1900227 Positive regulation of NLRP3 inflammasome complex assembly
Process GO:1900407 Regulation of cellular response to oxidative stress
Process GO:1901214 Regulation of neuron death
Process GO:1901216 Positive regulation of neuron death
Process GO:1901222 Regulation of NIK/NF-kappaB signaling
Process GO:1901224 Positive regulation of NIK/NF-kappaB signaling
Process GO:1901564 Organonitrogen compound metabolic process
Process GO:1901576 Organic substance biosynthetic process
Process GO:1901652 Response to peptide
Process GO:1901653 Cellular response to peptide
Process GO:1901654 Response to ketone
Process GO:1901698 Response to nitrogen compound
Process GO:1901699 Cellular response to nitrogen compound
Process GO:1901700 Response to oxygen-containing compound
Process GO:1901701 Cellular response to oxygen-containing compound
Process GO:1902531 Regulation of intracellular signal transduction
Process GO:1902532 Negative regulation of intracellular signal transduction
Process GO:1902533 Positive regulation of intracellular signal transduction
Process GO:1902680 Positive regulation of RNA biosynthetic process
Process GO:1902882 Regulation of response to oxidative stress
Process GO:1903201 Regulation of oxidative stress-induced cell death
Process GO:1903203 Regulation of oxidative stress-induced neuron death
Process GO:1903209 Positive regulation of oxidative stress-induced cell death
Process GO:1903223 Positive regulation of oxidative stress-induced neuron death
Process GO:1903426 Regulation of reactive oxygen species biosynthetic process
Process GO:1903428 Positive regulation of reactive oxygen species biosynthetic process
Process GO:1903506 Regulation of nucleic acid-templated transcription
Process GO:1903508 Positive regulation of nucleic acid-templated transcription
Process GO:1903530 Regulation of secretion by cell
Process GO:1903532 Positive regulation of secretion by cell
Process GO:1903555 Regulation of tumor necrosis factor superfamily cytokine production
Process GO:1903556 Negative regulation of tumor necrosis factor superfamily cytokine production
Process GO:1903557 Positive regulation of tumor necrosis factor superfamily cytokine production
Process GO:1903829 Positive regulation of protein localization
Process GO:1903969 Regulation of response to macrophage colony-stimulating factor
Process GO:1903971 Positive regulation of response to macrophage colony-stimulating factor
Process GO:1903972 Regulation of cellular response to macrophage colony-stimulating factor stimulus
Process GO:1903974 Positive regulation of cellular response to macrophage colony-stimulating factor stimulus
Process GO:1904407 Positive regulation of nitric oxide metabolic process
Process GO:1904464 Regulation of matrix metallopeptidase secretion
Process GO:1904466 Positive regulation of matrix metallopeptidase secretion
Process GO:1904645 Response to amyloid-beta
Process GO:1904646 Cellular response to amyloid-beta
Process GO:1904951 Positive regulation of establishment of protein localization
Process GO:1990267 Response to transition metal nanoparticle
Process GO:1990268 Response to gold nanoparticle
Process GO:2000145 Regulation of cell motility
Process GO:2000147 Positive regulation of cell motility
Process GO:2000341 Regulation of chemokine (C-X-C motif) ligand 2 production
Process GO:2000343 Positive regulation of chemokine (C-X-C motif) ligand 2 production
Process GO:2000377 Regulation of reactive oxygen species metabolic process
Process GO:2000379 Positive regulation of reactive oxygen species metabolic process
Process GO:2001057 Reactive nitrogen species metabolic process
Process GO:2001141 Regulation of RNA biosynthetic process
Component GO:0001726 Ruffle
Component GO:0001891 Phagocytic cup
Component GO:0005622 Intracellular anatomical structure
Component GO:0005737 Cytoplasm
Component GO:0005768 Endosome
Component GO:0005769 Early endosome
Component GO:0005794 Golgi apparatus
Component GO:0005886 Plasma membrane
Component GO:0005887 Integral component of plasma membrane
Component GO:0009897 External side of plasma membrane
Component GO:0009986 Cell surface
Component GO:0012505 Endomembrane system
Component GO:0016020 Membrane
Component GO:0016021 Integral component of membrane
Component GO:0031224 Intrinsic component of membrane
Component GO:0031226 Intrinsic component of plasma membrane
Component GO:0031252 Cell leading edge
Component GO:0031410 Cytoplasmic vesicle
Component GO:0031982 Vesicle
Component GO:0032991 Protein-containing complex
Component GO:0042995 Cell projection
Component GO:0043226 Organelle
Component GO:0043227 Membrane-bounded organelle
Component GO:0043229 Intracellular organelle
Component GO:0043231 Intracellular membrane-bounded organelle
Component GO:0043235 Receptor complex
Component GO:0046696 Lipopolysaccharide receptor complex
Component GO:0048471 Perinuclear region of cytoplasm
Component GO:0071944 Cell periphery
Component GO:0097708 Intracellular vesicle
Component GO:0098552 Side of membrane
Component GO:0098796 Membrane protein complex
Component GO:0110165 Cellular anatomical entity
Component GO:0120025 Plasma membrane bounded cell projection
Function GO:0001530 Lipopolysaccharide binding
Function GO:0001875 Lipopolysaccharide immune receptor activity
Function GO:0003824 Catalytic activity
Function GO:0003953 NAD+ nucleosidase activity
Function GO:0004888 Transmembrane signaling receptor activity
Function GO:0005102 Signaling receptor binding
Function GO:0005488 Binding
Function GO:0005515 Protein binding
Function GO:0008289 Lipid binding
Function GO:0016787 Hydrolase activity
Function GO:0016798 Hydrolase activity, acting on glycosyl bonds
Function GO:0016799 Hydrolase activity, hydrolyzing N-glycosyl compounds
Function GO:0038023 Signaling receptor activity
Function GO:0038187 Pattern recognition receptor activity
Function GO:0042802 Identical protein binding
Function GO:0043548 Phosphatidylinositol 3-kinase binding
Function GO:0046982 Protein heterodimerization activity
Function GO:0046983 Protein dimerization activity
Function GO:0050135 NAD(P)+ nucleosidase activity
Function GO:0060089 Molecular transducer activity
Function GO:0061809 NAD+ nucleotidase, cyclic ADP-ribose generating
Function GO:0097367 Carbohydrate derivative binding

Pathway annotation


Category Term ID Term description
RCTM RNO-166016 Toll Like Receptor 4 (TLR4) Cascade
RCTM RNO-166166 MyD88-independent TLR4 cascade
RCTM RNO-168249 Innate Immune System
RCTM RNO-168256 Immune System
RCTM RNO-168898 Toll-like Receptor Cascades
RCTM RNO-5686938 Regulation of TLR by endogenous ligand
RCTM RNO-936964 Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
RCTM RNO-937061 TRIF(TICAM1)-mediated TLR4 signaling
RCTM RNO-937072 TRAF6-mediated induction of TAK1 complex within TLR4 complex
WikiPathways WP1309 Toll-like receptor signaling pathway
WikiPathways WP1487 TNF-alpha and mucus production in lung epythelium
WikiPathways WP2433 Spinal cord injury
KEGG rno04064 NF-kappa B signaling pathway
KEGG rno04066 HIF-1 signaling pathway
KEGG rno04145 Phagosome
KEGG rno04151 PI3K-Akt signaling pathway
KEGG rno04217 Necroptosis
KEGG rno04613 Neutrophil extracellular trap formation
KEGG rno04620 Toll-like receptor signaling pathway
KEGG rno04621 NOD-like receptor signaling pathway
KEGG rno04936 Alcoholic liver disease
KEGG rno05132 Salmonella infection
KEGG rno05133 Pertussis
KEGG rno05134 Legionellosis
KEGG rno05135 Yersinia infection
KEGG rno05140 Leishmaniasis
KEGG rno05142 Chagas disease
KEGG rno05144 Malaria
KEGG rno05145 Toxoplasmosis
KEGG rno05146 Amoebiasis
KEGG rno05152 Tuberculosis
KEGG rno05161 Hepatitis B
KEGG rno05162 Measles
KEGG rno05164 Influenza A
KEGG rno05170 Human immunodeficiency virus 1 infection
KEGG rno05171 Coronavirus disease - COVID-19
KEGG rno05205 Proteoglycans in cancer
KEGG rno05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
KEGG rno05321 Inflammatory bowel disease
KEGG rno05323 Rheumatoid arthritis
KEGG rno05417 Lipid and atherosclerosis

Expression profile of Tlr4 in omics data



ID GSE100499
Title Exploring acupuncture mechanism in preconditioning of IRI
Organism Rattus norvegicus
GSM Sample info Characteristics Value
GSM2685201 MX1 tissue: Myocardium gender: male 8.462646
GSM2685202 MX2 tissue: Myocardium gender: female 8.207417
GSM2685203 MX3 tissue: Myocardium gender: female 8.190743
GSM2685204 MX4 tissue: Myocardium gender: male 7.971996
GSM2685205 DZ1 tissue: Myocardium gender: male 8.832187
GSM2685206 DZ2 tissue: Myocardium gender: male 8.796437
GSM2685207 DZ3 tissue: Myocardium gender: female 8.661495
GSM2685208 DZ4 tissue: Myocardium gender: female 8.717609
GSM2685209 JJ1 tissue: Myocardium gender: male 7.3940573
GSM2685210 JJ2 tissue: Myocardium gender: female 7.9503956
GSM2685211 JJ3 tissue: Myocardium gender: female 8.1690855
GSM2685212 JJ4 tissue: Myocardium gender: male 8.279181
GSM2685213 NG1 tissue: Myocardium gender: male 8.343096
GSM2685214 NG2 tissue: Myocardium gender: female 8.653005
GSM2685215 NG3 tissue: Myocardium gender: male 8.498728
GSM2685216 NG4 tissue: Myocardium gender: female 8.3435135
GSM2685217 YL1 tissue: Myocardium gender: male 8.257747
GSM2685218 YL2 tissue: Myocardium gender: male 8.483019
GSM2685219 YL3 tissue: Myocardium gender: female 7.9177036
GSM2685220 YL4 tissue: Myocardium gender: female 8.073249
GSM2685221 QC1 tissue: Myocardium gender: male 8.3259735
GSM2685222 QC2 tissue: Myocardium gender: male 8.234259
GSM2685223 QC3 tissue: Myocardium gender: female 8.558352
GSM2685224 QC4 tissue: Myocardium gender: female 8.059407

ID GSE136833
Title Effects of lidocaine on the expression of rat spinal cord
Organism Rattus norvegicus
GSM Sample info Characteristics Value
GSM4058984 Control_1 strain: Sprague-Dawley tissue: Lumbar segment of spinal cord 3.957507148
GSM4058985 Control_2 strain: Sprague-Dawley tissue: Lumbar segment of spinal cord 4.147527023
GSM4058986 Control_3 strain: Sprague-Dawley tissue: Lumbar segment of spinal cord 3.927289585
GSM4058987 Lidocaine_1 strain: Sprague-Dawley tissue: Lumbar segment of spinal cord 4.817603754
GSM4058988 Lidocaine_2 strain: Sprague-Dawley tissue: Lumbar segment of spinal cord 4.4661425
GSM4058989 Lidocaine_3 strain: Sprague-Dawley tissue: Lumbar segment of spinal cord 4.610438035

ID GSE138454
Title Impact of inflammation on hepatic subcellular energetics in anesthetized rats
Organism Rattus norvegicus
GSM Sample info Characteristics Value
GSM4108997 Sample 1 Isoflurane sepsis anesthetic background: Isoflurane strain: Sprague-Dawley age: 10 weeks old sepsis/control: sepsis gender: male 61.0
GSM4108998 Sample 2 Isoflurane sepsis anesthetic background: Isoflurane strain: Sprague-Dawley age: 10 weeks old sepsis/control: sepsis gender: male 31.0
GSM4108999 Sample 3 Isoflurane sepsis anesthetic background: Isoflurane strain: Sprague-Dawley age: 10 weeks old sepsis/control: sepsis gender: male 33.0
GSM4109000 Sample 4 Isoflurane sepsis anesthetic background: Isoflurane strain: Sprague-Dawley age: 10 weeks old sepsis/control: sepsis gender: male 43.0
GSM4109001 Sample 5 Isoflurane control anesthetic background: Isoflurane strain: Sprague-Dawley age: 10 weeks old sepsis/control: control gender: male 43.0
GSM4109002 Sample 6 Isoflurane control anesthetic background: Isoflurane strain: Sprague-Dawley age: 10 weeks old sepsis/control: control gender: male 34.0
GSM4109003 Sample 7 Isoflurane control anesthetic background: Isoflurane strain: Sprague-Dawley age: 10 weeks old sepsis/control: control gender: male 36.0
GSM4109004 Sample 8 Isoflurane control anesthetic background: Isoflurane strain: Sprague-Dawley age: 10 weeks old sepsis/control: control gender: male 84.0
GSM4109005 Sample9 Propofol sepsis anesthetic background: Propofol strain: Sprague-Dawley age: 10 weeks old sepsis/control: sepsis gender: male 28.0
GSM4109006 Sample10 Propofol sepsis anesthetic background: Propofol strain: Sprague-Dawley age: 10 weeks old sepsis/control: sepsis gender: male 44.0
GSM4109007 Sample11 Propofol sepsis anesthetic background: Propofol strain: Sprague-Dawley age: 10 weeks old sepsis/control: sepsis gender: male 36.0
GSM4109008 Sample12 Propofol sepsis anesthetic background: Propofol strain: Sprague-Dawley age: 10 weeks old sepsis/control: sepsis gender: male 57.0
GSM4109009 Sample13 Propofol control anesthetic background: Propofol strain: Sprague-Dawley age: 10 weeks old sepsis/control: control gender: male 29.0
GSM4109010 Sample14 Propofol control anesthetic background: Propofol strain: Sprague-Dawley age: 10 weeks old sepsis/control: control gender: male 37.0
GSM4109011 Sample 15 Propofol control anesthetic background: Propofol strain: Sprague-Dawley age: 10 weeks old sepsis/control: control gender: male 32.0
GSM4109012 Sample16 Propofol control anesthetic background: Propofol strain: Sprague-Dawley age: 10 weeks old sepsis/control: control gender: male 29.0

ID GSE139220
Title Expression data from sevoflurane anesthesia treated rat
Organism Rattus norvegicus
GSM Sample info Characteristics Value
GSM4134285 Brain_Control_rep1 strain: Sprague-Dawley age: 18-month old treatment: control tissue: hippocampus 4.66952
GSM4134286 Brain_Control_rep2 strain: Sprague-Dawley age: 18-month old treatment: control tissue: hippocampus 4.773402
GSM4134287 Brain_Control_rep3 strain: Sprague-Dawley age: 18-month old treatment: control tissue: hippocampus 4.738794
GSM4134288 Brain_Sevoflurane_rep1 strain: Sprague-Dawley age: 18-month old treatment: sevoflurane anesthesia tissue: hippocampus 4.657917
GSM4134289 Brain_Sevoflurane_rep2 strain: Sprague-Dawley age: 18-month old treatment: sevoflurane anesthesia tissue: hippocampus 4.827937
GSM4134290 Brain_Sevoflurane_rep3 strain: Sprague-Dawley age: 18-month old treatment: sevoflurane anesthesia tissue: hippocampus 5.183744

ID GSE143895
Title GPR160 de-orphanization reveals critical roles in neuropathic pain in rodents
Organism Rattus norvegicus
GSM Sample info Characteristics Value
GSM4276356 dhsc01 strain: Sprague Dawley tissue: DHSC treatment: CCI 4.722
GSM4276357 dhsc03 strain: Sprague Dawley tissue: DHSC treatment: CCI 6.912
GSM4276358 dhsc05 strain: Sprague Dawley tissue: DHSC treatment: CCI 6.442
GSM4276359 dhsc13 strain: Sprague Dawley tissue: DHSC treatment: SHAM 2.682
GSM4276360 dhsc15 strain: Sprague Dawley tissue: DHSC treatment: SHAM 2.007

ID GSE157924
Title Regulation of acupuncture on genes in brain stem
Organism Rattus norvegicus
GSM Sample info Characteristics Value
GSM4780973 Rattus_JSSZ(Sham) tissue: Rattus brainstem of modeling treatment: Sham 5.861863406
GSM4780974 Rattus_JXZ(Hand Acu) tissue: Rattus brainstem of modeling treatment: Hand Acu 6.12176893
GSM4780975 Rattus_MXZ(TBI) tissue: Rattus brainstem of modeling treatment: TBI 5.505044397

ID GSE1616
Title Genomics of preconditioning
Organism Rattus norvegicus
GSM Sample info Characteristics Value
GSM27484 APC_a (anesthetic-preconditioning, 1st replicate) 48.400000000000006
GSM27485 APC_b (anesthetic-preconditioning, 2nd replicate) 36.4
GSM27486 APC_c (anesthetic-preconditioning, 3rd replicate) 30.5
GSM27487 APC_d (anesthetic-preconditioning, 4th replicate) 21.349999999999998
GSM27488 APC_e (anesthetic-preconditioning, 5th replicate) 7.9
GSM27489 APC_TRI_a (trigger of anesthetic-preconditioning, 1st replicate) 46.45
GSM27490 APC_TRI_b (trigger of anesthetic-preconditioning, 2nd replicate) 30.400000000000002
GSM27491 APC_TRI_c (trigger of anesthetic-preconditioning, 3rd replicate) 34.35
GSM27492 APC_TRI_d (trigger of anesthetic-preconditioning, 4th replicate) 52.6
GSM27493 APC_TRI_e (trigger of anesthetic-preconditioning, 5th replicate) 61.25
GSM27494 CTL_a (control, 1st replicate) 56.05
GSM27495 CTL_b (control, 2nd replicate) 55.2
GSM27496 CTL_c (control, 3rd replicate) 50.650000000000006
GSM27497 CTL_d (control, 4th replicate) 48.25
GSM27498 CTL_e (control, 5th replicate) 51.55
GSM27499 IPC_a (ischemic preconditioning, 1st replicate) 19.299999999999997
GSM27500 IPC_b (ischemic preconditioning, 2nd replicate) 31.85
GSM27501 IPC_c (ischemic preconditioning, 3rd replicate) 10.45
GSM27502 IPC_d (ischemic preconditioning, 4th replicate) 44.7
GSM27503 IPC_e (ischemic preconditioning, 5th replicate) 58.050000000000004
GSM27504 IPC_TRI_a (trigger of ischemic preconditioning, 1st replicate) 89.1
GSM27505 IPC_TRI_b (trigger of ischemic preconditioning, 2nd replicate) 84.15
GSM27506 IPC_TRI_c (trigger of ischemic preconditioning, 3rd replicate) 20.2
GSM27507 IPC_TRI_d (trigger of ischemic preconditioning, 4th replicate) 100.69999999999999
GSM27508 IPC_TRI_e (trigger of ischemic preconditioning, 5th replicate) 74.55000000000001
GSM27509 ISCH_a (ischemia, 1st replicate) 50.85
GSM27510 ISCH_b (ischemia, 2nd replicate) 19.8
GSM27511 ISCH_c (ischemia, 3rd replicate) 46.849999999999994
GSM27512 ISCH_d (ischemia, 4th replicate) 49.95
GSM27513 ISCH_e (ischemia, 5th replicate) 32.55

ID GSE1779
Title Effect of Isoflurane and LTM on basolateral amygdala
Organism Rattus norvegicus
GSM Sample info Characteristics Value
GSM30790 baseline control 01 male, 275-300g 134.4
GSM30791 baseline control 02 male, 275-300g 103.3
GSM30792 baseline control 03 male, 275-300g 82.4
GSM30793 baseline control 04 male, 275-300g 108.3
GSM30794 baseline control 05 male, 275-300g 53.9
GSM30795 baseline control 06 male, 275-300g 60.3
GSM30796 baseline control 07 male, 275-300g 91.6
GSM30797 baseline control 08 male, 275-300g 75.7
GSM30798 baseline control 09 male, 275-300g 127.8
GSM30799 pain 01 94.5
GSM30800 pain 02 90.8
GSM30801 pain 03 158.4
GSM30802 pain 04 90.1
GSM30803 pain 05 102.0
GSM30804 FC 01 87.6
GSM30805 FC 02 98.2
GSM30806 FC 03 100.2
GSM30807 FC 04 101.2
GSM30808 FC 05 104.3
GSM30809 IFC 01 88.2
GSM30810 IFC 02 64.6
GSM30811 IFC 03 102.0
GSM30812 IFC 04 72.6
GSM30813 IFC 05 65.1
GSM99800 isoflurane 01 male, 275-300g 53.4
GSM99801 isoflurane 02 male, 275-300g 77.7
GSM99802 isoflurane 03 male, 275-300g 89.1
GSM99803 isoflurane 04 male, 275-300g 65.9
GSM99804 isoflurane 05 male, 275-300g 86.7

ID GSE190472
Title Study on VEGF regulation mechanism of acupuncture improving endometrial receptivity in IVF-ET
Organism Rattus norvegicus
GSM Sample info Characteristics Value
GSM5724271 model 21 Sex: female tissue: Uterine tissue condition: model 35.1117
GSM5724272 model 22 Sex: female tissue: Uterine tissue condition: model 61.9797
GSM5724273 model 23 Sex: female tissue: Uterine tissue condition: model 55.6179
GSM5724274 treatment31 Sex: female tissue: Uterine tissue condition: treatment 33.4737
GSM5724275 treatment32 Sex: female tissue: Uterine tissue condition: treatment 30.4857
GSM5724276 treatment33 Sex: female tissue: Uterine tissue condition: treatment 41.5666
GSM5724277 control 41 Sex: female tissue: Uterine tissue condition: control 94.3086
GSM5724278 control 42 Sex: female tissue: Uterine tissue condition: control 98.8274
GSM5724279 control 43 Sex: female tissue: Uterine tissue condition: control 35.2004

ID GSE192399
Title Gene expression of brain regions activated by sevoflurane and propofol
Organism Rattus norvegicus
GSM Sample info Characteristics Value
GSM5746332 LHb, Sevoflurane, 60mins brain region: the lateral habenula (LHb) treatment: Sevoflurane 6.27359
GSM5746333 LHb, O2, 60mins brain region: the lateral habenula (LHb) treatment: O2 6.63872
GSM5746334 MHb, Sevoflurane, 60mins brain region: the medial habenula (MHb) treatment: Sevoflurane 6.11161
GSM5746335 MHb, O2, 60mins brain region: the medial habenula (MHb) treatment: O2 6.23123
GSM5746336 Sol, Sevoflurane, 60mins brain region: the solitary nucleus (Sol) treatment: Sevoflurane 6.84815
GSM5746337 Sol, O2, 60mins brain region: the solitary nucleus (Sol) treatment: O2 7.20504
GSM5746338 Mve, Sevoflurane, 60mins brain region: the medial vestibular nucleus (MVe) treatment: Sevoflurane 6.19937
GSM5746339 Mve, O2, 60mins brain region: the medial vestibular nucleus (MVe) treatment: O2 5.89459
GSM5746340 LHb, Propofol, 60mins brain region: the lateral habenula (LHb) treatment: Propofol 5.23224
GSM5746341 LHb, Intralipos, 60mins brain region: the lateral habenula (LHb) treatment: Intralipos 5.82536
GSM5746342 MHb, Propofol, 60mins brain region: the medial habenula (MHb) treatment: Propofol 4.97535
GSM5746343 MHb, Intralipos, 60mins brain region: the medial habenula (MHb) treatment: Intralipos 5.24747
GSM5746344 Sol, Propofol, 60mins brain region: the solitary nucleus (Sol) treatment: Propofol 6.80787
GSM5746345 Sol, Intralipos, 60mins brain region: the solitary nucleus (Sol) treatment: Intralipos 6.32172
GSM5746346 MVe, Propofol, 60mins brain region: the medial vestibular nucleus (MVe) treatment: Propofol 5.26247
GSM5746347 MVe, Intralipos, 60mins brain region: the medial vestibular nucleus (MVe) treatment: Intralipos 6.01081

ID GSE205202
Title Hepatic responses of mice and rats to equivalent acetaminophen (APAP) insult [rat]
Organism Rattus norvegicus
GSM Sample info Characteristics Value
GSM6208507 Rat_Baseline_0h_1 tissue: liver strain: Sprague-Dawley Sex: male treatment: Untreated hours after treatment: 0 5.977467
GSM6208508 Rat_Baseline_0h_2 tissue: liver strain: Sprague-Dawley Sex: male treatment: Untreated hours after treatment: 0 5.84201
GSM6208509 Rat_Baseline_0h_3 tissue: liver strain: Sprague-Dawley Sex: male treatment: Untreated hours after treatment: 0 5.855313
GSM6208510 Rat_Baseline_0h_4 tissue: liver strain: Sprague-Dawley Sex: male treatment: Untreated hours after treatment: 0 5.943258
GSM6208511 Rat_Baseline_0h_5 tissue: liver strain: Sprague-Dawley Sex: male treatment: Untreated hours after treatment: 0 5.672891
GSM6208512 Rat_Vehicle_03h_1 tissue: liver strain: Sprague-Dawley Sex: male treatment: Vehicle (1% [w/v] hydroxyethylcellulose, o.g.) hours after treatment: 3 5.616481
GSM6208513 Rat_Vehicle_03h_2 tissue: liver strain: Sprague-Dawley Sex: male treatment: Vehicle (1% [w/v] hydroxyethylcellulose, o.g.) hours after treatment: 3 5.53543
GSM6208514 Rat_Vehicle_03h_3 tissue: liver strain: Sprague-Dawley Sex: male treatment: Vehicle (1% [w/v] hydroxyethylcellulose, o.g.) hours after treatment: 3 5.731469
GSM6208515 Rat_Vehicle_03h_4 tissue: liver strain: Sprague-Dawley Sex: male treatment: Vehicle (1% [w/v] hydroxyethylcellulose, o.g.) hours after treatment: 3 5.682885
GSM6208516 Rat_Vehicle_03h_5 tissue: liver strain: Sprague-Dawley Sex: male treatment: Vehicle (1% [w/v] hydroxyethylcellulose, o.g.) hours after treatment: 3 5.631557
GSM6208517 Rat_Vehicle_06h_1 tissue: liver strain: Sprague-Dawley Sex: male treatment: Vehicle (1% [w/v] hydroxyethylcellulose, o.g.) hours after treatment: 6 5.928929
GSM6208518 Rat_Vehicle_06h_2 tissue: liver strain: Sprague-Dawley Sex: male treatment: Vehicle (1% [w/v] hydroxyethylcellulose, o.g.) hours after treatment: 6 5.882288
GSM6208519 Rat_Vehicle_06h_3 tissue: liver strain: Sprague-Dawley Sex: male treatment: Vehicle (1% [w/v] hydroxyethylcellulose, o.g.) hours after treatment: 6 5.803864
GSM6208520 Rat_Vehicle_06h_4 tissue: liver strain: Sprague-Dawley Sex: male treatment: Vehicle (1% [w/v] hydroxyethylcellulose, o.g.) hours after treatment: 6 5.762831
GSM6208521 Rat_Vehicle_06h_5 tissue: liver strain: Sprague-Dawley Sex: male treatment: Vehicle (1% [w/v] hydroxyethylcellulose, o.g.) hours after treatment: 6 5.839064
GSM6208522 Rat_Vehicle_09h_1 tissue: liver strain: Sprague-Dawley Sex: male treatment: Vehicle (1% [w/v] hydroxyethylcellulose, o.g.) hours after treatment: 9 5.879435
GSM6208523 Rat_Vehicle_09h_2 tissue: liver strain: Sprague-Dawley Sex: male treatment: Vehicle (1% [w/v] hydroxyethylcellulose, o.g.) hours after treatment: 9 5.759542
GSM6208524 Rat_Vehicle_09h_3 tissue: liver strain: Sprague-Dawley Sex: male treatment: Vehicle (1% [w/v] hydroxyethylcellulose, o.g.) hours after treatment: 9 5.72298
GSM6208525 Rat_Vehicle_09h_4 tissue: liver strain: Sprague-Dawley Sex: male treatment: Vehicle (1% [w/v] hydroxyethylcellulose, o.g.) hours after treatment: 9 5.838703
GSM6208526 Rat_Vehicle_09h_5 tissue: liver strain: Sprague-Dawley Sex: male treatment: Vehicle (1% [w/v] hydroxyethylcellulose, o.g.) hours after treatment: 9 5.779212
GSM6208527 Rat_Vehicle_24h_1 tissue: liver strain: Sprague-Dawley Sex: male treatment: Vehicle (1% [w/v] hydroxyethylcellulose, o.g.) hours after treatment: 24 5.92692
GSM6208528 Rat_Vehicle_24h_2 tissue: liver strain: Sprague-Dawley Sex: male treatment: Vehicle (1% [w/v] hydroxyethylcellulose, o.g.) hours after treatment: 24 5.687002
GSM6208529 Rat_Vehicle_24h_3 tissue: liver strain: Sprague-Dawley Sex: male treatment: Vehicle (1% [w/v] hydroxyethylcellulose, o.g.) hours after treatment: 24 5.965592
GSM6208530 Rat_Vehicle_24h_4 tissue: liver strain: Sprague-Dawley Sex: male treatment: Vehicle (1% [w/v] hydroxyethylcellulose, o.g.) hours after treatment: 24 5.623206
GSM6208531 Rat_Vehicle_24h_5 tissue: liver strain: Sprague-Dawley Sex: male treatment: Vehicle (1% [w/v] hydroxyethylcellulose, o.g.) hours after treatment: 24 5.66926
GSM6208532 Rat_APAP_03h_1 tissue: liver strain: Sprague-Dawley Sex: male treatment: 1000 mg/kg acetamnophen (o.g.) hours after treatment: 3 5.373699
GSM6208533 Rat_APAP_03h_2 tissue: liver strain: Sprague-Dawley Sex: male treatment: 1000 mg/kg acetamnophen (o.g.) hours after treatment: 3 5.68239
GSM6208534 Rat_APAP_03h_3 tissue: liver strain: Sprague-Dawley Sex: male treatment: 1000 mg/kg acetamnophen (o.g.) hours after treatment: 3 5.52515
GSM6208535 Rat_APAP_03h_4 tissue: liver strain: Sprague-Dawley Sex: male treatment: 1000 mg/kg acetamnophen (o.g.) hours after treatment: 3 5.522195
GSM6208536 Rat_APAP_03h_5 tissue: liver strain: Sprague-Dawley Sex: male treatment: 1000 mg/kg acetamnophen (o.g.) hours after treatment: 3 5.561044
GSM6208537 Rat_APAP_06h_1 tissue: liver strain: Sprague-Dawley Sex: male treatment: 1000 mg/kg acetamnophen (o.g.) hours after treatment: 6 5.806939
GSM6208538 Rat_APAP_06h_2 tissue: liver strain: Sprague-Dawley Sex: male treatment: 1000 mg/kg acetamnophen (o.g.) hours after treatment: 6 5.66592
GSM6208539 Rat_APAP_06h_3 tissue: liver strain: Sprague-Dawley Sex: male treatment: 1000 mg/kg acetamnophen (o.g.) hours after treatment: 6 5.863648
GSM6208540 Rat_APAP_06h_4 tissue: liver strain: Sprague-Dawley Sex: male treatment: 1000 mg/kg acetamnophen (o.g.) hours after treatment: 6 5.367738
GSM6208541 Rat_APAP_06h_5 tissue: liver strain: Sprague-Dawley Sex: male treatment: 1000 mg/kg acetamnophen (o.g.) hours after treatment: 6 5.997664
GSM6208542 Rat_APAP_09h_1 tissue: liver strain: Sprague-Dawley Sex: male treatment: 1000 mg/kg acetamnophen (o.g.) hours after treatment: 9 5.868613
GSM6208543 Rat_APAP_09h_2 tissue: liver strain: Sprague-Dawley Sex: male treatment: 1000 mg/kg acetamnophen (o.g.) hours after treatment: 9 5.977252
GSM6208544 Rat_APAP_09h_3 tissue: liver strain: Sprague-Dawley Sex: male treatment: 1000 mg/kg acetamnophen (o.g.) hours after treatment: 9 5.966136
GSM6208545 Rat_APAP_09h_4 tissue: liver strain: Sprague-Dawley Sex: male treatment: 1000 mg/kg acetamnophen (o.g.) hours after treatment: 9 5.83294
GSM6208546 Rat_APAP_09h_5 tissue: liver strain: Sprague-Dawley Sex: male treatment: 1000 mg/kg acetamnophen (o.g.) hours after treatment: 9 5.775516
GSM6208547 Rat_APAP_24h_1 tissue: liver strain: Sprague-Dawley Sex: male treatment: 1000 mg/kg acetamnophen (o.g.) hours after treatment: 24 5.854792
GSM6208548 Rat_APAP_24h_2 tissue: liver strain: Sprague-Dawley Sex: male treatment: 1000 mg/kg acetamnophen (o.g.) hours after treatment: 24 5.861604
GSM6208549 Rat_APAP_24h_3 tissue: liver strain: Sprague-Dawley Sex: male treatment: 1000 mg/kg acetamnophen (o.g.) hours after treatment: 24 6.1004
GSM6208550 Rat_APAP_24h_4 tissue: liver strain: Sprague-Dawley Sex: male treatment: 1000 mg/kg acetamnophen (o.g.) hours after treatment: 24 5.735818
GSM6208551 Rat_APAP_24h_5 tissue: liver strain: Sprague-Dawley Sex: male treatment: 1000 mg/kg acetamnophen (o.g.) hours after treatment: 24 5.73928

ID GSE232804
Title EGR3 regulates opioid-related nociception and motivation in male rats
Organism Rattus norvegicus
GSM Sample info Characteristics Value
GSM7383519 ww01_Saline_Saline tissue: Brain / mPFC pain: Saline drug: Salin 31.0
GSM7383520 ww02_Saline_Saline tissue: Brain / mPFC pain: Saline drug: Saline 29.0
GSM7383521 ww03_Saline_Saline tissue: Brain / mPFC pain: Saline drug: Salin 27.0
GSM7383522 ww05_Saline_Saline tissue: Brain / mPFC pain: Saline drug: Saline 25.0
GSM7383523 ww06_Saline_Saline tissue: Brain / mPFC pain: Saline drug: Salin 29.0
GSM7383524 ww07_Saline_Saline tissue: Brain / mPFC pain: Saline drug: Saline 26.0
GSM7383525 ww08_Saline_Saline tissue: Brain / mPFC pain: Saline drug: Salin 25.0
GSM7383526 ww10_Saline_Saline tissue: Brain / mPFC pain: Saline drug: Saline 27.0
GSM7383527 ww12_Saline_OXY tissue: Brain / mPFC pain: Saline drug: OXY 23.0
GSM7383528 ww13_Saline_OXY tissue: Brain / mPFC pain: Saline drug: OXY 47.0
GSM7383529 ww14_Saline_OXY tissue: Brain / mPFC pain: Saline drug: OXY 27.0
GSM7383530 ww15_Saline_OXY tissue: Brain / mPFC pain: Saline drug: OXY 26.0
GSM7383531 ww16_Saline_OXY tissue: Brain / mPFC pain: Saline drug: OXY 40.0
GSM7383532 ww17_Saline_OXY tissue: Brain / mPFC pain: Saline drug: OXY 38.0
GSM7383533 ww18_Saline_OXY tissue: Brain / mPFC pain: Saline drug: OXY 32.0
GSM7383534 ww20_Saline_OXY tissue: Brain / mPFC pain: Saline drug: OXY 36.0
GSM7383535 ww21_CFA_Saline tissue: Brain / mPFC pain: CFA drug: Saline 28.0
GSM7383536 ww22_CFA_Saline tissue: Brain / mPFC pain: CFA drug: Saline 29.0
GSM7383537 ww23_CFA_Saline tissue: Brain / mPFC pain: CFA drug: Saline 22.0
GSM7383538 ww24_CFA_Saline tissue: Brain / mPFC pain: CFA drug: Saline 24.0
GSM7383539 ww26_CFA_Saline tissue: Brain / mPFC pain: CFA drug: Saline 40.0
GSM7383540 ww27_CFA_Saline tissue: Brain / mPFC pain: CFA drug: Saline 35.0
GSM7383541 ww28_CFA_Saline tissue: Brain / mPFC pain: CFA drug: Saline 36.0
GSM7383542 ww30_CFA_Saline tissue: Brain / mPFC pain: CFA drug: Saline 37.0
GSM7383543 ww31_CFA_OXY tissue: Brain / mPFC pain: CFA drug: OXY 28.0
GSM7383544 ww32_CFA_OXY tissue: Brain / mPFC pain: CFA drug: OXY 24.0
GSM7383545 ww34_CFA_OXY tissue: Brain / mPFC pain: CFA drug: OXY 28.0
GSM7383546 ww35_CFA_OXY tissue: Brain / mPFC pain: CFA drug: OXY 30.0
GSM7383547 ww36_CFA_OXY tissue: Brain / mPFC pain: CFA drug: OXY 32.0
GSM7383548 ww37_CFA_OXY tissue: Brain / mPFC pain: CFA drug: OXY 46.0
GSM7383549 ww38_CFA_OXY tissue: Brain / mPFC pain: CFA drug: OXY 27.0
GSM7383550 www09_Saline_Saline tissue: Brain / mPFC pain: Saline drug: Saline 42.0
GSM7383551 www19_Saline_OXY tissue: Brain / mPFC pain: Saline drug: OXY 43.0
GSM7383552 www29_CFA_Saline tissue: Brain / mPFC pain: CFA drug: Saline 28.0
GSM7383553 www33_CFA_OXY tissue: Brain / mPFC pain: CFA drug: OXY 30.0
GSM7383554 www39_CFA_OXY tissue: Brain / mPFC pain: CFA drug: OXY 21.0

ID GSE244436
Title Similarity and dissimilarity in alteration of gene expression profile associated with inhalational anesthesia between sevoflurane and desflurane
Organism Rattus norvegicus
GSM Sample info Characteristics Value
GSM7816143 Liver, Control for SevoAnes tissue: liver genotype: wild type treatment: Control for SevoAnes 4.831138
GSM7816144 Liver, Anesthetized with sevoflurane for 6 h tissue: liver genotype: wild type treatment: Anesthetized with sevoflurane for 6 h 3.04337
GSM7816145 Liver, Control for DesAnes tissue: liver genotype: wild type treatment: Control for DesAnes 2.951334
GSM7816146 Liver, Anesthetized with desflurane for 6 h tissue: liver genotype: wild type treatment: Anesthetized with desflurane for 6 h 3.253749

ID GSE359
Title Isoflurane Single Exposures
Organism Rattus norvegicus
GSM Sample info Characteristics Value
GSM5120 Isoflurane single exposure control-1 9.0
GSM5121 Isoflurane single exposure control-2 3.4499999999999997
GSM5122 Isoflurane single exposure control-3 4.15
GSM5124 Isoflurane single exposure 1 hr-1 26.599999999999998
GSM5126 Isoflurane single exposure 1 hr-2 9.55
GSM5127 Isoflurane single exposure 2 hr-1 9.5
GSM5130 Isoflurane single exposure 2 hr-2 9.899999999999999
GSM5131 Isoflurane single exposure 2 hr-3 2.8499999999999996

ID GSE48025
Title Affymetrix Chip Data of the Transcriptome of the Rheumatoid Arthritis Rat Model Treated with Acupuncture (Affymetrix, mRNA, batch1)
Organism Rattus norvegicus
GSM Sample info Characteristics Value
GSM1165929 RAT_NORA_T0_1 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: healthy rats before therapy 4.777764629
GSM1165930 RAT_NORA_T0_2 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: healthy rats before therapy 4.630939757
GSM1165931 RAT_RA_T0_1 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats before therapy 3.975733491
GSM1165932 RAT_RA_T0_2 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats before therapy 4.32729874
GSM1165933 RAT_NORA_1h_1 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: healthy rats at 1 hour after therapy 4.188915205
GSM1165934 RAT_NORA_1h_2 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: healthy rats at 1 hour after therapy 4.027094439
GSM1165935 RAT_AP_1h_1 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 1 hour acupuncture therapy 3.899755949
GSM1165936 RAT_AP_1h_2 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 1 hour acupuncture therapy 3.634558966
GSM1165937 RAT_MTX_1h_1 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 1 hour MTX therapy 4.424192098
GSM1165938 RAT_MTX_1h_2 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 1 hour MTX therapy 4.068137134
GSM1165939 RAT_ANE_1h_1 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 1 hour ANE therapy 3.843986505
GSM1165940 RAT_ANE_1h_2 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 1 hour ANE therapy 4.769257003
GSM1165941 RAT_PLA_1h_1 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 1 hour placebo therapy 4.347358434
GSM1165942 RAT_PLA_1h_2 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 1 hour placebo therapy 4.050096926
GSM1165943 RAT_NORA_34d_1 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: healthy rats at 34 days after therapy 3.718404658
GSM1165944 RAT_NORA_34d_2 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: healthy rats at 34 days after therapy 3.941253031
GSM1165945 RAT_AP_34d_1 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 34 days acupuncture therapy 3.601622949
GSM1165946 RAT_AP_34d_2 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 34 days acupuncture therapy 3.62210537
GSM1165947 RAT_MTX_34d_1 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 34 days MTX therapy 3.538324663
GSM1165948 RAT_MTX_34d_2 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 34 days MTX therapy 3.875205714
GSM1165949 RAT_ANE_34d_1 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 34 days ANE therapy 4.599495791
GSM1165950 RAT_ANE_34d_2 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 34 days ANE therapy 4.5754024
GSM1165951 RAT_PLA_34d_1 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 34 days placebo therapy 3.691916095
GSM1165952 RAT_PLA_34d_2 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 34 days placebo therapy 3.90574588

ID GSE53897
Title Genome-wide analysis of dorsal root ganglion (DRG) gene expression after morphine or oxycodone treatment
Organism Rattus norvegicus
GSM Sample info Characteristics Value
GSM1303240 DRG RVM1 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 5.631241
GSM1303241 DRG RVM2 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 5.726966
GSM1303242 DRG RVM3 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 5.744302
GSM1303243 DRG RVM7 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 5.677616
GSM1303244 DRG RVOx2 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 5.812035
GSM1303245 DRG RVOx3 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 5.755195
GSM1303246 DRG RVOx5 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 5.633294
GSM1303247 DRG RVOx7 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 5.596176
GSM1303248 DRG RVS4 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 5.657194
GSM1303249 DRG RVS5 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 5.770803
GSM1303250 DRG RVS6 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 5.600556
GSM1303251 DRG RVS7 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 5.746243
GSM1303252 DRG RSM1 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 5.611125
GSM1303253 DRG RSM2 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 5.692627
GSM1303254 DRG RSM4 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 5.639578
GSM1303255 DRG RSM5 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 5.559058
GSM1303256 DRG RSOx1 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 5.83247
GSM1303257 DRG RSOx2 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 5.611215
GSM1303258 DRG RSOx3 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 5.662741
GSM1303259 DRG RSOx4 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 5.679669
GSM1303260 DRG RSS1 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 5.812107
GSM1303261 DRG RSS2 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 5.711249
GSM1303262 DRG RSS3 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 5.722644
GSM1303263 DRG RSS6 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 5.634528

ID GSE55573
Title Using DNA microarray to screen intracellular signal pathways of hypoglycemic activity by electroacupuncture of Zusanli (ST36) acupoints in streptozotocin-induced rats with diabetes
Organism Rattus norvegicus
GSM Sample info Characteristics Value
GSM1339443 Mock skeletal muscle strain: Wistar age: 8-10 week-old gender: Male 125.1649
GSM1339444 EA (electroacupuncture) skeletal muscle strain: Wistar age: 8-10 week-old gender: Male 119.5054

ID GSE58456
Title Affymetrix Chip Data of the Transcriptome of the Rheumatoid Arthritis Rat Model Treated with Acupuncture (Affymetrix, mRNA, batch 2)
Organism Rattus norvegicus
GSM Sample info Characteristics Value
GSM1693996 Peripheral blood mononuclear cells from NORA before therapy, replicate 1 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: healthy rats before therapy 96.0562455
GSM1693997 Peripheral blood mononuclear cells from NORA before therapy, replicate 2 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: healthy rats before therapy 54.07401633
GSM1693998 Peripheral blood mononuclear cells from NORA before therapy, replicate 3 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: healthy rats before therapy 62.52301015
GSM1693999 Peripheral blood mononuclear cells from RA before therapy, replicate 1 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: rheumatoid arthritis rats before therapy 60.91106498
GSM1694000 Peripheral blood mononuclear cells from RA before therapy, replicate 2 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: rheumatoid arthritis rats before therapy 63.53953263
GSM1694001 Peripheral blood mononuclear cells from HAP after 34 days acupuncture therapy, replicate 1 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: healthy rats after 34 days acupuncture therapy 56.10212362
GSM1694002 Peripheral blood mononuclear cells from HAP after 34 days acupuncture therapy, replicate 2 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: healthy rats after 34 days acupuncture therapy 14.68967764
GSM1694003 Peripheral blood mononuclear cells from HAP after 34 days acupuncture therapy, replicate 3 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: healthy rats after 34 days acupuncture therapy 83.21685925
GSM1694004 Peripheral blood mononuclear cells from AP after 34 days acupuncture therapy, replicate 1 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: rheumatoid arthritis rats after 34 days acupuncture therapy 56.49636596
GSM1694005 Peripheral blood mononuclear cells from AP after 34 days acupuncture therapy, replicate 2 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: rheumatoid arthritis rats after 34 days acupuncture therapy 91.22348839
GSM1694006 Peripheral blood mononuclear cells from AP after 34 days acupuncture therapy, replicate 3 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: rheumatoid arthritis rats after 34 days acupuncture therapy 174.533144
GSM1694007 Peripheral blood mononuclear cells from MTXAP after 34 days MTX&acupuncture therapy, replicate 1 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: rheumatoid arthritis rats after 34 days methotrexate & acupuncture therapy 42.34008671
GSM1694008 Peripheral blood mononuclear cells from MTXAP after 34 days MTX&acupuncture therapy, replicate 2 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: rheumatoid arthritis rats after 34 days methotrexate & acupuncture therapy 78.82115683
GSM1694009 Peripheral blood mononuclear cells from MTXAP after 34 days MTX&acupuncture therapy, replicate 3 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: rheumatoid arthritis rats after 34 days methotrexate & acupuncture therapy 43.88114359

ID GSE58460
Title Rheumatoid Arthritis Rat Model Treated with Acupuncture
Organism Rattus norvegicus
GSM Sample info Characteristics Value
GSM1165929 RAT_NORA_T0_1 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: healthy rats before therapy 4.777764629
GSM1165930 RAT_NORA_T0_2 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: healthy rats before therapy 4.630939757
GSM1165931 RAT_RA_T0_1 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats before therapy 3.975733491
GSM1165932 RAT_RA_T0_2 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats before therapy 4.32729874
GSM1165933 RAT_NORA_1h_1 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: healthy rats at 1 hour after therapy 4.188915205
GSM1165934 RAT_NORA_1h_2 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: healthy rats at 1 hour after therapy 4.027094439
GSM1165935 RAT_AP_1h_1 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 1 hour acupuncture therapy 3.899755949
GSM1165936 RAT_AP_1h_2 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 1 hour acupuncture therapy 3.634558966
GSM1165937 RAT_MTX_1h_1 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 1 hour MTX therapy 4.424192098
GSM1165938 RAT_MTX_1h_2 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 1 hour MTX therapy 4.068137134
GSM1165939 RAT_ANE_1h_1 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 1 hour ANE therapy 3.843986505
GSM1165940 RAT_ANE_1h_2 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 1 hour ANE therapy 4.769257003
GSM1165941 RAT_PLA_1h_1 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 1 hour placebo therapy 4.347358434
GSM1165942 RAT_PLA_1h_2 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 1 hour placebo therapy 4.050096926
GSM1165943 RAT_NORA_34d_1 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: healthy rats at 34 days after therapy 3.718404658
GSM1165944 RAT_NORA_34d_2 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: healthy rats at 34 days after therapy 3.941253031
GSM1165945 RAT_AP_34d_1 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 34 days acupuncture therapy 3.601622949
GSM1165946 RAT_AP_34d_2 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 34 days acupuncture therapy 3.62210537
GSM1165947 RAT_MTX_34d_1 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 34 days MTX therapy 3.538324663
GSM1165948 RAT_MTX_34d_2 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 34 days MTX therapy 3.875205714
GSM1165949 RAT_ANE_34d_1 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 34 days ANE therapy 4.599495791
GSM1165950 RAT_ANE_34d_2 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 34 days ANE therapy 4.5754024
GSM1165951 RAT_PLA_34d_1 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 34 days placebo therapy 3.691916095
GSM1165952 RAT_PLA_34d_2 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 34 days placebo therapy 3.90574588
GSM1412003 RAT_NORA_T0_1 strain: Wistar gender: Female tissue: RAT Peripheral blood mononuclear cells
GSM1412004 RAT_NORA_T0_2 strain: Wistar gender: Female tissue: RAT Peripheral blood mononuclear cells
GSM1412005 RAT_RA_T0_1 strain: Wistar gender: Female tissue: RAT Peripheral blood mononuclear cells
GSM1412006 RAT_RA_T0_2 strain: Wistar gender: Female tissue: RAT Peripheral blood mononuclear cells
GSM1412007 RAT_NORA_1h_1 strain: Wistar gender: Female tissue: RAT Peripheral blood mononuclear cells
GSM1412008 RAT_NORA_1h_2 strain: Wistar gender: Female tissue: RAT Peripheral blood mononuclear cells
GSM1412009 RAT_AP_1h_1 strain: Wistar gender: Female tissue: RAT Peripheral blood mononuclear cells
GSM1412010 RAT_AP_1h_2 strain: Wistar gender: Female tissue: RAT Peripheral blood mononuclear cells
GSM1412011 RAT_MTX_1h_1 strain: Wistar gender: Female tissue: RAT Peripheral blood mononuclear cells
GSM1412012 RAT_MTX_1h_2 strain: Wistar gender: Female tissue: RAT Peripheral blood mononuclear cells
GSM1412013 RAT_ANE_1h_1 strain: Wistar gender: Female tissue: RAT Peripheral blood mononuclear cells
GSM1412014 RAT_ANE_1h_2 strain: Wistar gender: Female tissue: RAT Peripheral blood mononuclear cells
GSM1412015 RAT_PLA_1h_1 strain: Wistar gender: Female tissue: RAT Peripheral blood mononuclear cells
GSM1412016 RAT_PLA_1h_2 strain: Wistar gender: Female tissue: RAT Peripheral blood mononuclear cells
GSM1412017 RAT_NORA_34d_1 strain: Wistar gender: Female tissue: RAT Peripheral blood mononuclear cells
GSM1412018 RAT_NORA_34d_2 strain: Wistar gender: Female tissue: RAT Peripheral blood mononuclear cells
GSM1412019 RAT_AP_34d_1 strain: Wistar gender: Female tissue: RAT Peripheral blood mononuclear cells
GSM1412020 RAT_AP_34d_2 strain: Wistar gender: Female tissue: RAT Peripheral blood mononuclear cells
GSM1412021 RAT_MTX_34d_1 strain: Wistar gender: Female tissue: RAT Peripheral blood mononuclear cells
GSM1412022 RAT_MTX_34d_2 strain: Wistar gender: Female tissue: RAT Peripheral blood mononuclear cells
GSM1412023 RAT_ANE_34d_1 strain: Wistar gender: Female tissue: RAT Peripheral blood mononuclear cells
GSM1412024 RAT_ANE_34d_2 strain: Wistar gender: Female tissue: RAT Peripheral blood mononuclear cells
GSM1412025 RAT_PLA_34d_1 strain: Wistar gender: Female tissue: RAT Peripheral blood mononuclear cells
GSM1412026 RAT_PLA_34d_2 strain: Wistar gender: Female tissue: RAT Peripheral blood mononuclear cells
GSM1412027 RAT_RA_T0_1 strain: Wistar gender: Female tissue: RAT Sub-epidermidis muscle tissue
GSM1412028 RAT_RA_T0_2 strain: Wistar gender: Female tissue: RAT Sub-epidermidis muscle tissue
GSM1412029 RAT_AP_1h_1 strain: Wistar gender: Female tissue: RAT Sub-epidermidis muscle tissue
GSM1412030 RAT_AP_1h_2 strain: Wistar gender: Female tissue: RAT Sub-epidermidis muscle tissue
GSM1412031 RAT_PLA_1h_1 strain: Wistar gender: Female tissue: RAT Sub-epidermidis muscle tissue
GSM1412032 RAT_PLA_1h_2 strain: Wistar gender: Female tissue: RAT Sub-epidermidis muscle tissue
GSM1412033 RAT_AP_34d_1 strain: Wistar gender: Female tissue: RAT Sub-epidermidis muscle tissue
GSM1412034 RAT_AP_34d_2 strain: Wistar gender: Female tissue: RAT Sub-epidermidis muscle tissue
GSM1412035 RAT_PLA_34d_1 strain: Wistar gender: Female tissue: RAT Sub-epidermidis muscle tissue
GSM1412036 RAT_PLA_34d_2 strain: Wistar gender: Female tissue: RAT Sub-epidermidis muscle tissue
GSM1693996 Peripheral blood mononuclear cells from NORA before therapy, replicate 1 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: healthy rats before therap 96.0562455
GSM1693997 Peripheral blood mononuclear cells from NORA before therapy, replicate 2 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: healthy rats before therapy 54.07401633
GSM1693998 Peripheral blood mononuclear cells from NORA before therapy, replicate 3 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: healthy rats before therapy 62.52301015
GSM1693999 Peripheral blood mononuclear cells from RA before therapy, replicate 1 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: rheumatoid arthritis rats before therapy 60.91106498
GSM1694000 Peripheral blood mononuclear cells from RA before therapy, replicate 2 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: rheumatoid arthritis rats before therapy 63.53953263
GSM1694001 Peripheral blood mononuclear cells from HAP after 34 days acupuncture therapy, replicate 1 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: healthy rats after 34 days acupuncture therapy 56.10212362
GSM1694002 Peripheral blood mononuclear cells from HAP after 34 days acupuncture therapy, replicate 2 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: healthy rats after 34 days acupuncture therap 14.68967764
GSM1694003 Peripheral blood mononuclear cells from HAP after 34 days acupuncture therapy, replicate 3 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: healthy rats after 34 days acupuncture therapy 83.21685925
GSM1694004 Peripheral blood mononuclear cells from AP after 34 days acupuncture therapy, replicate 1 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: rheumatoid arthritis rats after 34 days acupuncture therapy 56.49636596
GSM1694005 Peripheral blood mononuclear cells from AP after 34 days acupuncture therapy, replicate 2 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: rheumatoid arthritis rats after 34 days acupuncture therapy 91.22348839
GSM1694006 Peripheral blood mononuclear cells from AP after 34 days acupuncture therapy, replicate 3 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: rheumatoid arthritis rats after 34 days acupuncture therapy 174.533144
GSM1694007 Peripheral blood mononuclear cells from MTXAP after 34 days MTX&acupuncture therapy, replicate 1 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: rheumatoid arthritis rats after 34 days methotrexate & acupuncture therapy 42.34008671
GSM1694008 Peripheral blood mononuclear cells from MTXAP after 34 days MTX&acupuncture therapy, replicate 2 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: rheumatoid arthritis rats after 34 days methotrexate & acupuncture therapy 78.82115683
GSM1694009 Peripheral blood mononuclear cells from MTXAP after 34 days MTX&acupuncture therapy, replicate 3 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: rheumatoid arthritis rats after 34 days methotrexate & acupuncture therapy 43.88114359

ID GSE752
Title Halothane/Isoflurane Repetitive Exposures
Organism Rattus norvegicus
GSM Sample info Characteristics Value
GSM5082 Control 1 4.8
GSM5084 Control 2 4.6
GSM5085 Control 3 5.9
GSM5086 Control 4 13.95
GSM5087 Control 5 10.0
GSM5090 Control 6 8.4
GSM5105 Control 7 14.75
GSM5106 Control 8 9.8
GSM5107 Control 9 10.55
GSM5108 Halothane 10 exposure-1 10.25
GSM5109 Halothane 10 exposures-2 8.75
GSM5110 Halothane 10 exposures-3 16.1
GSM5111 Halothane 5 exposures-1 12.0
GSM5112 Halothane 5 exposures-2 19.15
GSM5113 Halothane 5 exposures-3 17.35
GSM5114 Isoflurane 10 exposures-1 12.850000000000001
GSM5115 Isoflurane 10 exposures-2 17.85
GSM5116 Isoflurane 10 exposures-3 10.95
GSM5117 Isoflurane 5 exposures-1 16.9
GSM5118 Isoflurane 5 exposures-2 15.0
GSM5119 Isoflurane 5 exposures-3 8.85
GSM11379 Control 10 11.350000000000001
GSM11380 Control 11 8.299999999999999
GSM11381 Control 12 3.3499999999999996

ID GSE8911
Title Skeletal muscle after fine needle stimulation
Organism Rattus norvegicus
GSM Sample info Characteristics Value
GSM225891 Skeletal muscle sample from fine needle-stimulated hindlimb Strain: Lewis, Gender: Male, Body Weight: 275g, Tissue: Skeletal muscle sample from fine nnedle-stimulated hindlimb 32.1984
GSM225892 Skeletal muscle sample from control hindlimb Strain: Lewis, Gender: Male, Body weight: 275g, Tissue: skeletal muscle sample from non fine needle-stimulated hindlimb 36.7663