Gene Information
|
Gene Name
|
ABCC4 |
|
Gene ID
|
10257
|
|
Gene Full Name
|
ATP binding cassette subfamily C member 4 (PEL blood group) |
|
Gene Alias
|
MOAT-B|MOATB|MRP4 |
|
Transcripts
|
ENSG00000125257
|
|
Virus
|
HTLV1 |
|
Gene Type
|
protein-coding |
|
HPA Location Info
|
Plasma membrane;Golgi apparatus, Vesicles; 
|
|
Membrane Info
|
Enzymes, Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters |
|
Uniport_ID
|
O15439
|
|
HGNC ID
|
HGNC:55
|
|
OMIM ID
|
605250 |
|
Summary
|
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This family member plays a role in cellular detoxification as a pump for its substrate, organic anions. It may also function in prostaglandin-mediated cAMP signaling in ciliogenesis. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Sep 2014] |
Target gene [ABCC4] related to VISs 
Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section
| DVID |
Chromosome |
HM |
TFBS |
CA |
Sum of Overlapped Records |
Detail |
| 6002979 |
chr13 |
179 |
12 |
3 |
194 |
View |
| 6009863 |
chr13 |
17 |
5 |
12 |
34 |
View |
| 6014426 |
chr13 |
1 |
12 |
3 |
16 |
View |
| 6014600 |
chr13 |
15 |
1 |
0 |
16 |
View |
| 6018084 |
chr13 |
9 |
0 |
0 |
9 |
View |
| 6025483 |
chr13 |
2 |
1 |
0 |
3 |
View |
Target gene [ABCC4] related to Omics data
| Data ID |
Experiment type |
Sample number |
Platform |
|
GSE189602
|
Methylation profiling (Array) |
4 |
Infinium MethylationEPIC |
|
C GSE94732
|
Chip-seq |
24 |
Illumina NextSeq 500 (Homo sapiens);illumina Genome Analyzer IIx (Homo sapiens) |
|
GSE52244
|
Expression array |
15 |
[HuEx-1_0-st] Affymetrix Human Exon 1.0 ST Array [probe set (exon) version] |
|
GSE10789
|
Expression array |
6 |
NCI/ATC Hs-OperonV3 |
|
GSE224047
|
RNA-seq |
10 |
Illumina NextSeq 500 (Homo sapiens) |
|
GSE168557
|
Expression array |
6 |
Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Feature Number version) |
|
GSE136189
|
Methylation profiling (Array) |
40 |
Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482);Illumina Infinium HumanMethylation850 BeadChip |
When the gene can detect a peak in the dataset, a peak plot will be displayed.
> Dataset: GSE94732 - ABCC4 peak across samples
|
Peak Plot
|
|
|
HTLV1 Target gene Detail Information
