Gene Information
|
Gene Name
|
ADAMTS13 |
|
Gene ID
|
11093
|
|
Gene Full Name
|
ADAM metallopeptidase with thrombospondin type 1 motif 13 |
|
Gene Alias
|
ADAM-TS13|ADAMTS-13|C9orf8|VWFCP|vWF-CP |
|
Transcripts
|
ENSG00000160323
|
|
Virus
|
HTLV1 |
|
Gene Type
|
protein-coding |
|
HPA Location Info
|
Vesicles;Nucleoplasm;Secreted to blood; 
|
|
Membrane Info
|
Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins |
|
Uniport_ID
|
Q76LX8
|
|
HGNC ID
|
HGNC:1366
|
|
OMIM ID
|
604134 |
|
Summary
|
This gene encodes a member of a family of proteins containing several distinct regions, including a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. The enzyme encoded by this gene specifically cleaves von Willebrand Factor (vWF). Defects in this gene are associated with thrombotic thrombocytopenic purpura. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013] |
Target gene [ADAMTS13] related to VISs 
Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section
| DVID |
Chromosome |
HM |
TFBS |
CA |
Sum of Overlapped Records |
Detail |
| 6004525 |
chr9 |
26 |
84 |
3 |
113 |
View |
| 6013214 |
chr9 |
8 |
11 |
1 |
20 |
View |
Target gene [ADAMTS13] related to Omics data
| Data ID |
Experiment type |
Sample number |
Platform |
|
C GSE94732
|
Chip-seq |
24 |
Illumina NextSeq 500 (Homo sapiens);illumina Genome Analyzer IIx (Homo sapiens) |
|
GSE168557
|
Expression array |
6 |
Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Feature Number version) |
|
GSE52244
|
Expression array |
15 |
[HuEx-1_0-st] Affymetrix Human Exon 1.0 ST Array [probe set (exon) version] |
|
GSE10789
|
Expression array |
6 |
NCI/ATC Hs-OperonV3 |
|
GSE189602
|
Methylation profiling (Array) |
4 |
Infinium MethylationEPIC |
|
GSE136189
|
Methylation profiling (Array) |
40 |
Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482);Illumina Infinium HumanMethylation850 BeadChip |
When the gene can detect a peak in the dataset, a peak plot will be displayed.
> Dataset: GSE94732 - ADAMTS13 peak across samples
|
Peak Plot
|
|
|
HTLV1 Target gene Detail Information
