Gene Information
|
Gene Name
|
ADAMTS14 |
|
Gene ID
|
140766
|
|
Gene Full Name
|
ADAM metallopeptidase with thrombospondin type 1 motif 14 |
|
Gene Alias
|
- |
|
Transcripts
|
ENSG00000138316
|
|
Virus
|
HTLV1 |
|
Gene Type
|
protein-coding |
|
HPA Location Info
|
Golgi apparatus, Vesicles;Secreted to extracellular matrix; 
|
|
Membrane Info
|
Cancer-related genes, Plasma proteins, Predicted secreted proteins |
|
Uniport_ID
|
Q8WXS8
|
|
HGNC ID
|
HGNC:14899
|
|
OMIM ID
|
607506 |
|
Summary
|
This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The encoded preproprotein is proteolytically processed to generate the mature enzyme. This enzyme cleaves amino-terminal propeptides from type I procollagen, a necessary step in the formation of collagen fibers. Mutations in this gene may be associated with osteoarthritis in human patients. [provided by RefSeq, May 2016] |
Target gene [ADAMTS14] related to VISs 
Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section
| DVID |
Chromosome |
HM |
TFBS |
CA |
Sum of Overlapped Records |
Detail |
| 6007390 |
chr10 |
23 |
15 |
18 |
56 |
View |
| 6009927 |
chr10 |
32 |
2 |
0 |
34 |
View |
Target gene [ADAMTS14] related to Omics data
| Data ID |
Experiment type |
Sample number |
Platform |
|
C GSE94732
|
Chip-seq |
24 |
Illumina NextSeq 500 (Homo sapiens);illumina Genome Analyzer IIx (Homo sapiens) |
|
GSE168557
|
Expression array |
6 |
Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Feature Number version) |
|
GSE52244
|
Expression array |
15 |
[HuEx-1_0-st] Affymetrix Human Exon 1.0 ST Array [probe set (exon) version] |
|
GSE10789
|
Expression array |
6 |
NCI/ATC Hs-OperonV3 |
|
GSE189602
|
Methylation profiling (Array) |
4 |
Infinium MethylationEPIC |
|
GSE136189
|
Methylation profiling (Array) |
40 |
Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482);Illumina Infinium HumanMethylation850 BeadChip |
When the gene can detect a peak in the dataset, a peak plot will be displayed.
> Dataset: GSE94732 - ADAMTS14 peak across samples
|
Peak Plot
|
|
|
HTLV1 Target gene Detail Information
