Gene Information
|
Gene Name
|
ADAMTS3 |
|
Gene ID
|
9508
|
|
Gene Full Name
|
ADAM metallopeptidase with thrombospondin type 1 motif 3 |
|
Gene Alias
|
ADAMTS-4|HKLLS3 |
|
Transcripts
|
ENSG00000156140
|
|
Virus
|
HTLV1 |
|
Gene Type
|
protein-coding |
|
HPA Location Info
|
Intermediate filaments;Secreted to extracellular matrix; 
|
|
Membrane Info
|
Cancer-related genes, Disease related genes, Human disease related genes, Predicted secreted proteins |
|
Uniport_ID
|
O15072
|
|
HGNC ID
|
HGNC:219
|
|
OMIM ID
|
605011 |
|
Summary
|
This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The encoded preproprotein is proteolytically processed to generate the mature protease. This protease, a member of the procollagen aminopropeptidase subfamily of proteins, may play a role in the processing of type II fibrillar collagen in articular cartilage. [provided by RefSeq, Feb 2016] |
Target gene [ADAMTS3] related to VISs 
Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section
| DVID |
Chromosome |
HM |
TFBS |
CA |
Sum of Overlapped Records |
Detail |
| 6016098 |
chr4 |
6 |
6 |
1 |
13 |
View |
| 6022498 |
chr4 |
5 |
0 |
0 |
5 |
View |
| 6024893 |
chr4 |
2 |
1 |
0 |
3 |
View |
Target gene [ADAMTS3] related to Omics data
| Data ID |
Experiment type |
Sample number |
Platform |
|
C GSE94732
|
Chip-seq |
24 |
Illumina NextSeq 500 (Homo sapiens);illumina Genome Analyzer IIx (Homo sapiens) |
|
GSE168557
|
Expression array |
6 |
Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Feature Number version) |
|
GSE52244
|
Expression array |
15 |
[HuEx-1_0-st] Affymetrix Human Exon 1.0 ST Array [probe set (exon) version] |
|
GSE10789
|
Expression array |
6 |
NCI/ATC Hs-OperonV3 |
|
GSE189602
|
Methylation profiling (Array) |
4 |
Infinium MethylationEPIC |
|
GSE136189
|
Methylation profiling (Array) |
40 |
Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482);Illumina Infinium HumanMethylation850 BeadChip |
When the gene can detect a peak in the dataset, a peak plot will be displayed.
> Dataset: GSE94732 - ADAMTS3 peak across samples
|
Peak Plot
|
|
|
HTLV1 Target gene Detail Information
