HTLV1 Target gene Detail Information

> ADAMTS6 Gene Search Result


Gene Information
Gene Name ADAMTS6
Gene ID 11174
Gene Full Name ADAM metallopeptidase with thrombospondin type 1 motif 6
Gene Alias ADAM-TS 6|ADAM-TS6|ADAMTS-6
Transcripts ENSG00000049192
Virus HTLV1
Gene Type protein-coding
HPA Location Info Secreted to extracellular matrix;
Membrane Info Cancer-related genes, Predicted secreted proteins
Uniport_ID Q9UKP5
HGNC ID HGNC:222
OMIM ID 605008
Summary This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The encoded preproprotein is proteolytically processed to generate the mature enzyme. Expression of this gene may be regulated by the cytokine TNF-alpha. [provided by RefSeq, Mar 2016]
Target gene [ADAMTS6] related to VISs

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section


DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
6000573 chr5 1077 53 84 1214 View
6009121 chr5 37 2 0 39 View
6010610 chr5 28 2 0 30 View
6026827 chr5 0 2 0 2 View

Target gene [ADAMTS6] related to Omics data
Data ID Experiment type Sample number Platform
C
  GSE94732 		Chip-seq 24 Illumina NextSeq 500 (Homo sapiens);illumina Genome Analyzer IIx (Homo sapiens)
GSE168557 Expression array 6 Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Feature Number version)
GSE52244 Expression array 15 [HuEx-1_0-st] Affymetrix Human Exon 1.0 ST Array [probe set (exon) version]
GSE10789 Expression array 6 NCI/ATC Hs-OperonV3
GSE189602 Methylation profiling (Array) 4 Infinium MethylationEPIC
GSE136189 Methylation profiling (Array) 40 Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482);Illumina Infinium HumanMethylation850 BeadChip


When the gene can detect a peak in the dataset, a peak plot will be displayed.


> Dataset: GSE94732 - ADAMTS6 peak across samples

Peak Plot