Gene Information
|
Gene Name
|
ADH1B |
|
Gene ID
|
125
|
|
Gene Full Name
|
alcohol dehydrogenase 1B (class I), beta polypeptide |
|
Gene Alias
|
ADH2|HEL-S-117 |
|
Transcripts
|
ENSG00000196616
|
|
Virus
|
HBV |
|
Gene Type
|
protein-coding |
|
HPA Location Info
|
Plasma membrane, Cytosol;Nucleoplasm, Primary cilium, Primary cilium transition zone, Basal body; 
|
|
Membrane Info
|
Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins |
|
Uniport_ID
|
P00325
|
|
HGNC ID
|
HGNC:250
|
|
OMIM ID
|
103720 |
|
Summary
|
The protein encoded by this gene is a member of the alcohol dehydrogenase family. Members of this enzyme family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. This encoded protein, consisting of several homo- and heterodimers of alpha, beta, and gamma subunits, exhibits high activity for ethanol oxidation and plays a major role in ethanol catabolism. Three genes encoding alpha, beta and gamma subunits are tandemly organized in a genomic segment as a gene cluster. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2013] |
Target gene [ADH1B] related to VISs 
Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section
| DVID |
Chromosome |
HM |
TFBS |
CA |
Sum of Overlapped Records |
Detail |
| 1008754 |
chr4 |
14 |
5 |
0 |
19 |
View |
| 1010438 |
chr4 |
3 |
6 |
3 |
12 |
View |
| 1010499 |
chr4 |
0 |
11 |
1 |
12 |
View |
| 1010563 |
chr4 |
4 |
7 |
0 |
11 |
View |
| 1016194 |
chr4 |
0 |
1 |
0 |
1 |
View |
| 1017250 |
chr4 |
1 |
0 |
0 |
1 |
View |
| 1018161 |
chr4 |
0 |
0 |
0 |
0 |
View |
| 1018646 |
chr4 |
0 |
0 |
0 |
0 |
View |
| 1019735 |
chr4 |
0 |
0 |
0 |
0 |
View |
| 1024171 |
chr4 |
1 |
0 |
0 |
1 |
View |
| 1024686 |
chr4 |
0 |
0 |
0 |
0 |
View |
| 1040380 |
chr4 |
1 |
0 |
0 |
1 |
View |
| 1040381 |
chr4 |
1 |
0 |
0 |
1 |
View |
Target gene [ADH1B] related to Omics data
| Data ID |
Experiment type |
Sample number |
Platform |
|
S GSE252863
|
scRNA-seq |
10 |
Illumina HiSeq 2500 (Homo sapiens) |
|
GSE236281
|
RNA-seq |
12 |
Illumina MiSeq (Homo sapiens) |
|
C GSE68402
|
Chip-seq |
26 |
Illumina MiSeq (Homo sapiens);Illumina HiSeq 2500 (Homo sapiens) |
|
S GSE247322
|
scRNA-seq |
27 |
Illumina NovaSeq 6000 (Homo sapiens) |
|
TCGA_LIHC_HBV
|
DNA methylation sequencing;RNA-seq |
97 |
TCGA |
|
GSE224901
|
RNA-seq |
21 |
Illumina NovaSeq 6000 (Homo sapiens) |
|
E GSE100400
|
Chip-seq;RNA-seq;4C_cccDNA |
31 |
Illumina NextSeq 500 (Homo sapiens);Illumina NextSeq 500 (Mus musculus) |
|
GSE173897
|
RNA-seq |
95 |
Illumina HiSeq 4000 (Homo sapiens) |
|
GSE262515
|
RNA-seq |
21 |
Illumina HiSeq 2500 (Homo sapiens);Illumina HiSeq 2500 (Mus musculus) |
|
GSE110345
|
RNA-seq |
4 |
Illumina HiSeq 2500 (Homo sapiens) |
|
GSE131257
|
ATAC-seq;RNA-seq |
19 |
Illumina HiSeq 2500 (Homo sapiens) |
|
E GSE94660
|
RNA-seq |
42 |
Illumina HiSeq 2500 (Homo sapiens) |
When the query gene is differentially changed in the dataset, a volcano/bar plot will be displayed.
> Dataset: GSE100400 - ADH1B expression across samples
|
Volcano Plot
|
Bar Plot
|
> Dataset: GSE94660 - ADH1B expression across samples
|
Volcano Plot
|
Bar Plot
|
|
|
HBV Target gene Detail Information
