HTLV1 Target gene Detail Information

> AKR1C1 Gene Search Result

Gene Information

Gene Name	AKR1C1
Gene ID	1645
Gene Full Name	aldo-keto reductase family 1 member C1
Gene Alias	2-ALPHA-HSD\|20-ALPHA-HSD\|C9\|DD1\|DD1/DD2\|DDH\|DDH1\|H-37\|HAKRC\|HBAB\|MBAB
Transcripts	ENSG00000187134
Virus	HTLV1
Gene Type	protein-coding
HPA Location Info	Endoplasmic reticulum, Cytosol;
Membrane Info	Enzymes, Metabolic proteins, Predicted intracellular proteins
Uniport_ID	Q04828
HGNC ID	HGNC:384
OMIM ID	600449
Summary	This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reaction of progesterone to the inactive form 20-alpha-hydroxy-progesterone. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. [provided by RefSeq, Jul 2008]

Target gene [AKR1C1] related to VISs

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
6026560	chr10	2	0	0	2	View

Target gene [AKR1C1] related to Omics data

Data ID	Experiment type	Sample number	Platform
C GSE94732	Chip-seq	24	Illumina NextSeq 500 (Homo sapiens);illumina Genome Analyzer IIx (Homo sapiens)
GSE168557	Expression array	6	Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Feature Number version)
GSE52244	Expression array	15	[HuEx-1_0-st] Affymetrix Human Exon 1.0 ST Array [probe set (exon) version]
GSE10789	Expression array	6	NCI/ATC Hs-OperonV3
GSE189602	Methylation profiling (Array)	4	Infinium MethylationEPIC
M GSE136189	Methylation profiling (Array)	40	Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482);Illumina Infinium HumanMethylation850 BeadChip

When the query gene is differentially changed in the dataset, a volcano/bar plot will be displayed.

> Dataset: GSE94732 - AKR1C1 peak across samples
Peak Plot