Gene Name	ANKS1B
Gene ID	56899
Gene Full Name	ankyrin repeat and sterile alpha motif domain containing 1B
Gene Alias	AIDA|AIDA-1|ANKS2|EB-1|EB1|cajalin-2
Transcripts	ENSG00000185046
Virus	HBV
Gene Type	protein-coding
HPA Location Info	Nucleoplasm;Plasma membrane;
Membrane Info	Predicted intracellular proteins
Uniport_ID	Q7Z6G8
HGNC ID	HGNC:24600
OMIM ID	607815
Summary	This gene encodes a multi-domain protein that is predominantly expressed in brain and testis. This protein interacts with amyloid beta protein precursor (AbetaPP) and may have a role in normal brain development, and in the pathogenesis of Alzheimer's disease. Expression of this gene has been shown to be elevated in patients with pre-B cell acute lymphocytic leukemia associated with t(1;19) translocation. Alternatively spliced transcript variants encoding different isoforms (some with different subcellular localization, PMID:15004329) have been described for this gene. [provided by RefSeq, Aug 2011]

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1006808	chr12	14	16	3	33	View
1010384	chr12	3	9	0	12	View
1010684	chr12	3	8	0	11	View
1013012	chr12	6	0	0	6	View
1015551	chr12	1	1	0	2	View
1015729	chr12	1	1	0	2	View
1015730	chr12	1	1	0	2	View
1016111	chr12	2	0	0	2	View
1020414	chr12	1	1	0	2	View
1020416	chr12	1	0	0	1	View
1020417	chr12	3	0	0	3	View
1041992	chr12	4	1	0	5	View
1041993	chr12	4	0	0	4	View
1041994	chr12	0	0	0	0	View

Data ID	Experiment type	Sample number	Platform
GSE236281	RNA-seq	12	Illumina MiSeq (Homo sapiens)
C   GSE35465	Chip-seq;RNA-seq	6	Illumina HiSeq 2000 (Homo sapiens)
C   GSE68402	Chip-seq	26	Illumina MiSeq (Homo sapiens);Illumina HiSeq 2500 (Homo sapiens)
TCGA_LIHC_HBV	DNA methylation sequencing;RNA-seq	97	TCGA
C   GSE270130	Chip-seq	27	Illumina NovaSeq 6000 (Homo sapiens)
GSE224901	RNA-seq	21	Illumina NovaSeq 6000 (Homo sapiens)
GSE100400	Chip-seq;RNA-seq;4C_cccDNA	31	Illumina NextSeq 500 (Homo sapiens);Illumina NextSeq 500 (Mus musculus)
GSE173897	RNA-seq	95	Illumina HiSeq 4000 (Homo sapiens)
GSE262515	RNA-seq	21	Illumina HiSeq 2500 (Homo sapiens);Illumina HiSeq 2500 (Mus musculus)
GSE110345	RNA-seq	4	Illumina HiSeq 2500 (Homo sapiens)
C   GSE131257	ATAC-seq;RNA-seq	19	Illumina HiSeq 2500 (Homo sapiens)
E   GSE94660	RNA-seq	42	Illumina HiSeq 2500 (Homo sapiens)

• Expression profiling
• Genome binding/occupancy profiling

When the query gene is differentially changed in the dataset, a volcano/bar plot will be displayed.

> Dataset: GSE94660 - ANKS1B expression across samples

Volcano Plot

Bar Plot