HTLV1 Target gene Detail Information

> APBA2 Gene Search Result


Gene Information
Gene Name APBA2
Gene ID 321
Gene Full Name amyloid beta precursor protein binding family A member 2
Gene Alias D15S1518E|HsT16821|LIN-10|MGC:14091|MINT2|X11-BETA|X11L
Transcripts ENSG00000034053
Virus HTLV1
Gene Type protein-coding
HPA Location Info Golgi apparatus;
Membrane Info Predicted intracellular proteins, Transporters
Uniport_ID Q99767
HGNC ID HGNC:579
OMIM ID 602712
Summary The protein encoded by this gene is a member of the X11 protein family. It is a neuronal adapter protein that interacts with the Alzheimer's disease amyloid precursor protein (APP). It stabilizes APP and inhibits production of proteolytic APP fragments including the A beta peptide that is deposited in the brains of Alzheimer's disease patients. This gene product is believed to be involved in signal transduction processes. It is also regarded as a putative vesicular trafficking protein in the brain that can form a complex with the potential to couple synaptic vesicle exocytosis to neuronal cell adhesion. [provided by RefSeq, Jul 2017]
Target gene [APBA2] related to VISs

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section


DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
6003454 chr15 152 6 0 158 View
6009559 chr15 28 8 0 36 View
6025492 chr15 3 0 0 3 View
6027574 chr15 2 0 0 2 View

Target gene [APBA2] related to Omics data
Data ID Experiment type Sample number Platform
C
  GSE94732 		Chip-seq 24 Illumina NextSeq 500 (Homo sapiens);illumina Genome Analyzer IIx (Homo sapiens)
GSE168557 Expression array 6 Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Feature Number version)
GSE52244 Expression array 15 [HuEx-1_0-st] Affymetrix Human Exon 1.0 ST Array [probe set (exon) version]
GSE10789 Expression array 6 NCI/ATC Hs-OperonV3
GSE189602 Methylation profiling (Array) 4 Infinium MethylationEPIC
GSE136189 Methylation profiling (Array) 40 Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482);Illumina Infinium HumanMethylation850 BeadChip


When the gene can detect a peak in the dataset, a peak plot will be displayed.


> Dataset: GSE94732 - APBA2 peak across samples

Peak Plot