Gene Information
|
Gene Name
|
ARAP2 |
|
Gene ID
|
116984
|
|
Gene Full Name
|
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 |
|
Gene Alias
|
CENTD1|PARX |
|
Transcripts
|
ENSG00000047365
|
|
Virus
|
HTLV1 |
|
Gene Type
|
protein-coding |
|
HPA Location Info
|
Focal adhesion sites;Actin filaments;
|
|
Membrane Info
|
Predicted intracellular proteins |
|
Uniport_ID
|
Q8WZ64
|
|
HGNC ID
|
HGNC:16924
|
|
OMIM ID
|
606645 |
|
Summary
|
The protein encoded by this gene contains ARF-GAP, RHO-GAP, ankyrin repeat, RAS-associating, and pleckstrin homology domains. The protein is a phosphatidylinositol (3,4,5)-trisphosphate-dependent Arf6 GAP that binds RhoA-GTP, but it lacks the predicted catalytic arginine in the RHO-GAP domain and does not have RHO-GAP activity. The protein associates with focal adhesions and functions downstream of RhoA to regulate focal adhesion dynamics. [provided by RefSeq, Sep 2008] |
Target gene [ARAP2] related to VISs
Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section
| DVID |
Chromosome |
HM |
TFBS |
CA |
Sum of Overlapped Records |
Detail |
| 6016203 |
chr4 |
12 |
0 |
0 |
12 |
View |
| 6016227 |
chr4 |
12 |
0 |
0 |
12 |
View |
| 6016818 |
chr4 |
11 |
0 |
0 |
11 |
View |
| 6016823 |
chr4 |
10 |
1 |
0 |
11 |
View |
| 6019798 |
chr4 |
7 |
0 |
0 |
7 |
View |
Target gene [ARAP2] related to Omics data
| Data ID |
Experiment type |
Sample number |
Platform |
|
GSE189602
|
Methylation profiling (Array) |
4 |
Infinium MethylationEPIC |
|
C GSE94732
|
Chip-seq |
24 |
Illumina NextSeq 500 (Homo sapiens);illumina Genome Analyzer IIx (Homo sapiens) |
|
GSE52244
|
Expression array |
15 |
[HuEx-1_0-st] Affymetrix Human Exon 1.0 ST Array [probe set (exon) version] |
|
GSE10789
|
Expression array |
6 |
NCI/ATC Hs-OperonV3 |
|
GSE224047
|
RNA-seq |
10 |
Illumina NextSeq 500 (Homo sapiens) |
|
GSE168557
|
Expression array |
6 |
Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Feature Number version) |
|
GSE136189
|
Methylation profiling (Array) |
40 |
Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482);Illumina Infinium HumanMethylation850 BeadChip |
When the gene can detect a peak in the dataset, a peak plot will be displayed.
> Dataset: GSE94732 - ARAP2 peak across samples
|
Peak Plot
|
|
|