HTLV1 Target gene Detail Information

> ARHGAP35 Gene Search Result


Gene Information
Gene Name ARHGAP35
Gene ID 2909
Gene Full Name Rho GTPase activating protein 35
Gene Alias GRF-1|GRLF1|P190-A|P190A|p190ARhoGAP|p190RhoGAP
Transcripts ENSG00000160007
Virus HTLV1
Gene Type protein-coding
HPA Location Info Nuclear bodies;Microtubules, Aggresome;
Membrane Info Cancer-related genes, Predicted intracellular proteins
Uniport_ID Q9NRY4
HGNC ID HGNC:4591
OMIM ID 605277
Summary The human glucocorticoid receptor DNA binding factor, which associates with the promoter region of the glucocorticoid receptor gene (hGR gene), is a repressor of glucocorticoid receptor transcription. The amino acid sequence deduced from the cDNA sequences show the presence of three sequence motifs characteristic of a zinc finger and one motif suggestive of a leucine zipper in which 1 cysteine is found instead of all leucines. The GRLF1 enhances the homologous down-regulation of wild-type hGR gene expression. Biochemical analysis suggests that GRLF1 interaction is sequence specific and that transcriptional efficacy of GRLF1 is regulated through its interaction with specific sequence motif. The level of expression is regulated by glucocorticoids. [provided by RefSeq, Jul 2008]
Target gene [ARHGAP35] related to VISs

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section


DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
6021440 chr19 6 0 0 6 View

Target gene [ARHGAP35] related to Omics data
Data ID Experiment type Sample number Platform
GSE189602 Methylation profiling (Array) 4 Infinium MethylationEPIC
C
  GSE94732 		Chip-seq 24 Illumina NextSeq 500 (Homo sapiens);illumina Genome Analyzer IIx (Homo sapiens)
GSE52244 Expression array 15 [HuEx-1_0-st] Affymetrix Human Exon 1.0 ST Array [probe set (exon) version]
GSE10789 Expression array 6 NCI/ATC Hs-OperonV3
GSE224047 RNA-seq 10 Illumina NextSeq 500 (Homo sapiens)
GSE168557 Expression array 6 Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Feature Number version)


When the gene can detect a peak in the dataset, a peak plot will be displayed.


> Dataset: GSE94732 - ARHGAP35 peak across samples

Peak Plot