HTLV1 Target gene Detail Information

> ARHGAP42 Gene Search Result


Gene Information
Gene Name ARHGAP42
Gene ID 143872
Gene Full Name Rho GTPase activating protein 42
Gene Alias AD031|GRAF3|TMEM133
Transcripts ENSG00000165895
Virus HTLV1
Gene Type protein-coding
HPA Location Info Nuclear speckles;Cytosol;
Membrane Info Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID A6NI28
HGNC ID HGNC:26545
OMIM ID 615936
Summary This gene encodes a Rho GTPase-activating protein (RhoGAP), and member of the GRAF or BAR-PH family of proteins. Expression of this gene is enriched in vascular smooth muscle cells and the encoded protein inhibits RhoA activity to regulate vascular tone and control blood pressure. A mutation in the first intron of this gene modulates its expression and is associated with reduced blood pressure in human patients with borderline hypertension. [provided by RefSeq, Jul 2017]
Target gene [ARHGAP42] related to VISs

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section


DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
6001739 chr11 188 60 108 356 View
6017464 chr11 9 1 0 10 View
6017920 chr11 7 3 0 10 View
6029177 chr11 1 0 0 1 View

Target gene [ARHGAP42] related to Omics data
Data ID Experiment type Sample number Platform
C
  GSE94732 		Chip-seq 24 Illumina NextSeq 500 (Homo sapiens);illumina Genome Analyzer IIx (Homo sapiens)
GSE168557 Expression array 6 Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Feature Number version)
GSE52244 Expression array 15 [HuEx-1_0-st] Affymetrix Human Exon 1.0 ST Array [probe set (exon) version]
GSE10789 Expression array 6 NCI/ATC Hs-OperonV3
GSE189602 Methylation profiling (Array) 4 Infinium MethylationEPIC


When the gene can detect a peak in the dataset, a peak plot will be displayed.


> Dataset: GSE94732 - ARHGAP42 peak across samples

Peak Plot