Gene Name	ARHGEF26
Gene ID	26084
Gene Full Name	Rho guanine nucleotide exchange factor 26
Gene Alias	CSGEF|HMFN1864|SGEF
Transcripts	ENSG00000114790
Virus	HTLV1
Gene Type	protein-coding
HPA Location Info	Plasma membrane;Nucleoplasm, Cytosol;
Membrane Info	Predicted intracellular proteins
Uniport_ID	Q96DR7
HGNC ID	HGNC:24490
OMIM ID	617552
Summary	This gene encodes a member of the Rho-guanine nucleotide exchange factor (Rho-GEF) family. These proteins regulate Rho GTPases by catalyzing the exchange of GDP for GTP. The encoded protein specifically activates RhoG and plays a role in the promotion of macropinocytosis. Underexpression of the encoded protein may be a predictive marker of chemoresistant disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Oct 2011]

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
6003158	chr3	13	139	27	179	View
6004304	chr3	31	24	65	120	View
6016356	chr3	8	3	1	12	View
6017693	chr3	5	4	1	10	View
6029291	chr3	1	0	0	1	View
6031950	chr3	0	0	0	0	View

Data ID	Experiment type	Sample number	Platform
C   GSE94732	Chip-seq	24	Illumina NextSeq 500 (Homo sapiens);illumina Genome Analyzer IIx (Homo sapiens)
GSE168557	Expression array	6	Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Feature Number version)
GSE52244	Expression array	15	[HuEx-1_0-st] Affymetrix Human Exon 1.0 ST Array [probe set (exon) version]
GSE10789	Expression array	6	NCI/ATC Hs-OperonV3
GSE189602	Methylation profiling (Array)	4	Infinium MethylationEPIC

• Genome binding/occupancy profiling

When the gene can detect a peak in the dataset, a peak plot will be displayed.

> Dataset: GSE94732 - ARHGEF26 peak across samples

Peak Plot