Gene Name	BACH2
Gene ID	60468
Gene Full Name	BTB domain and CNC homolog 2
Gene Alias	BTBD25|IMD60
Transcripts	ENSG00000112182
Virus	HTLV1
Gene Type	protein-coding
HPA Location Info	Nucleoplasm;Cytosol;
Membrane Info	Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors
Uniport_ID	Q9BYV9
HGNC ID	HGNC:14078
OMIM ID	605394
Summary	Enables sequence-specific double-stranded DNA binding activity. Involved in primary adaptive immune response involving T cells and B cells. Located in cytosol and nucleoplasm. Part of RNA polymerase II transcription regulator complex. Implicated in immunodeficiency 60. [provided by Alliance of Genome Resources, Apr 2025]

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
6001485	chr6	218	125	74	417	View
6012022	chr6	22	2	0	24	View
6032233	chr6	0	0	0	0	View

Data ID	Experiment type	Sample number	Platform
GSE189602	Methylation profiling (Array)	4	Infinium MethylationEPIC
C   GSE94732	Chip-seq	24	Illumina NextSeq 500 (Homo sapiens);illumina Genome Analyzer IIx (Homo sapiens)
GSE52244	Expression array	15	[HuEx-1_0-st] Affymetrix Human Exon 1.0 ST Array [probe set (exon) version]
GSE10789	Expression array	6	NCI/ATC Hs-OperonV3
GSE224047	RNA-seq	10	Illumina NextSeq 500 (Homo sapiens)
GSE168557	Expression array	6	Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Feature Number version)
GSE136189	Methylation profiling (Array)	40	Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482);Illumina Infinium HumanMethylation850 BeadChip

• Genome binding/occupancy profiling

When the gene can detect a peak in the dataset, a peak plot will be displayed.

> Dataset: GSE94732 - BACH2 peak across samples

Peak Plot