HTLV1 Target gene Detail Information

> BCAT1 Gene Search Result


Gene Information
Gene Name BCAT1
Gene ID 586
Gene Full Name branched chain amino acid transaminase 1
Gene Alias BCATC|BCT1|ECA39|MECA39|PNAS121|PP18
Transcripts ENSG00000060982
Virus HTLV1
Gene Type protein-coding
HPA Location Info
Membrane Info Enzymes, Metabolic proteins, Predicted intracellular proteins
Uniport_ID P54687
HGNC ID HGNC:976
OMIM ID 113520
Summary This gene encodes the cytosolic form of the enzyme branched-chain amino acid transaminase. This enzyme catalyzes the reversible transamination of branched-chain alpha-keto acids to branched-chain L-amino acids essential for cell growth. Two different clinical disorders have been attributed to a defect of branched-chain amino acid transamination: hypervalinemia and hyperleucine-isoleucinemia. As there is also a gene encoding a mitochondrial form of this enzyme, mutations in either gene may contribute to these disorders. Alternatively spliced transcript variants have been described. [provided by RefSeq, May 2010]
Target gene [BCAT1] related to VISs

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section


DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
6000704 chr12 850 42 64 956 View
6008885 chr12 37 3 1 41 View
6013753 chr12 17 1 0 18 View
6024358 chr12 2 1 0 3 View

Target gene [BCAT1] related to Omics data
Data ID Experiment type Sample number Platform
GSE189602 Methylation profiling (Array) 4 Infinium MethylationEPIC
C
  GSE94732 		Chip-seq 24 Illumina NextSeq 500 (Homo sapiens);illumina Genome Analyzer IIx (Homo sapiens)
GSE52244 Expression array 15 [HuEx-1_0-st] Affymetrix Human Exon 1.0 ST Array [probe set (exon) version]
GSE10789 Expression array 6 NCI/ATC Hs-OperonV3
GSE224047 RNA-seq 10 Illumina NextSeq 500 (Homo sapiens)
GSE168557 Expression array 6 Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Feature Number version)
GSE136189 Methylation profiling (Array) 40 Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482);Illumina Infinium HumanMethylation850 BeadChip


When the gene can detect a peak in the dataset, a peak plot will be displayed.


> Dataset: GSE94732 - BCAT1 peak across samples

Peak Plot