Gene Name	BEAN1
Gene ID	146227
Gene Full Name	brain expressed associated with NEDD4 1
Gene Alias	BEAN|SCA31
Transcripts	ENSG00000166546
Virus	HTLV1
Gene Type	protein-coding
HPA Location Info	Nucleoplasm;Centrosome;
Membrane Info	Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID	Q3B7T3
HGNC ID	HGNC:24160
OMIM ID	612051
Summary	The protein encoded by this gene is one of several proteins that interact with NEDD4, a member of a family of ubiquitin-protein ligases. These proteins have PY motifs in common that bind to the WW domains of NEDD4. NEDD4 is developmentally regulated, and is highly expressed in embryonic tissues. Mutations in this gene (i.e., intronic insertions of >100 copies of pentanucleotide repeats including a (TGGAA)n sequence) are associated with spinocerebellar ataxia type 31. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2010]

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
6013804	chr16	17	1	0	18	View
6019990	chr16	3	4	0	7	View
6021301	chr16	6	0	0	6	View
6025501	chr16	0	1	2	3	View
6028150	chr16	0	1	0	1	View

Data ID	Experiment type	Sample number	Platform
GSE189602	Methylation profiling (Array)	4	Infinium MethylationEPIC
C   GSE94732	Chip-seq	24	Illumina NextSeq 500 (Homo sapiens);illumina Genome Analyzer IIx (Homo sapiens)
GSE52244	Expression array	15	[HuEx-1_0-st] Affymetrix Human Exon 1.0 ST Array [probe set (exon) version]
GSE224047	RNA-seq	10	Illumina NextSeq 500 (Homo sapiens)
GSE168557	Expression array	6	Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Feature Number version)

• Genome binding/occupancy profiling

When the gene can detect a peak in the dataset, a peak plot will be displayed.

> Dataset: GSE94732 - BEAN1 peak across samples

Peak Plot