HTLV1 Target gene Detail Information

> CACNA2D1 Gene Search Result


Gene Information
Gene Name CACNA2D1
Gene ID 781
Gene Full Name calcium voltage-gated channel auxiliary subunit alpha2delta 1
Gene Alias CACNA2|CACNL2A|CCHL2A|DEE110|LINC01112|lncRNA-N3
Transcripts ENSG00000153956
Virus HTLV1
Gene Type protein-coding
HPA Location Info Intracellular and membrane;
Membrane Info FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters
Uniport_ID P54289
HGNC ID HGNC:1399
OMIM ID 114204
Summary The preproprotein encoded by this gene is cleaved into multiple chains that comprise the alpha-2 and delta subunits of the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization. Mutations in this gene can cause cardiac deficiencies, including Brugada syndrome and short QT syndrome. Alternate splicing results in multiple transcript variants, some of which may lack the delta subunit portion. [provided by RefSeq, Nov 2014]
Target gene [CACNA2D1] related to VISs

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section


DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
6005987 chr7 60 13 4 77 View
6025047 chr7 3 0 0 3 View

Target gene [CACNA2D1] related to Omics data
Data ID Experiment type Sample number Platform
C
  GSE94732 		Chip-seq 24 Illumina NextSeq 500 (Homo sapiens);illumina Genome Analyzer IIx (Homo sapiens)
GSE168557 Expression array 6 Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Feature Number version)
GSE52244 Expression array 15 [HuEx-1_0-st] Affymetrix Human Exon 1.0 ST Array [probe set (exon) version]
GSE10789 Expression array 6 NCI/ATC Hs-OperonV3
GSE189602 Methylation profiling (Array) 4 Infinium MethylationEPIC
GSE136189 Methylation profiling (Array) 40 Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482);Illumina Infinium HumanMethylation850 BeadChip


When the gene can detect a peak in the dataset, a peak plot will be displayed.


> Dataset: GSE94732 - CACNA2D1 peak across samples

Peak Plot