Gene Information
|
Gene Name
|
CAMK2A |
|
Gene ID
|
815
|
|
Gene Full Name
|
calcium/calmodulin dependent protein kinase II alpha |
|
Gene Alias
|
CAMKA|CaMKIINalpha|CaMKIIalpha|MRD53|MRT63 |
|
Transcripts
|
ENSG00000070808
|
|
Virus
|
MCV |
|
Gene Type
|
protein-coding |
|
HPA Location Info
|
Plasma membrane, Primary cilium tip, Primary cilium transition zone, Principal piece;Cell Junctions, Perinuclear theca, Calyx, Connecting piece, End piece; 
|
|
Membrane Info
|
Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins |
|
Uniport_ID
|
Q9UQM7
|
|
HGNC ID
|
HGNC:1460
|
|
OMIM ID
|
114078 |
|
Summary
|
The product of this gene belongs to the serine/threonine protein kinases family, and to the Ca(2+)/calmodulin-dependent protein kinases subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. This calcium calmodulin-dependent protein kinase is composed of four different chains: alpha, beta, gamma, and delta. The alpha chain encoded by this gene is required for hippocampal long-term potentiation (LTP) and spatial learning. In addition to its calcium-calmodulin (CaM)-dependent activity, this protein can undergo autophosphorylation, resulting in CaM-independent activity. Several transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jun 2018] |
Target gene [CAMK2A] related to VISs 
Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section
| DVID |
Chromosome |
HM |
TFBS |
CA |
Sum of Overlapped Records |
Detail |
| 7000034 |
chr5 |
6525 |
5371 |
2020 |
13916 |
View |
Target gene [CAMK2A] related to Omics data
| Data ID |
Experiment type |
Sample number |
Platform |
|
C GSE147406
|
Chip-seq |
39 |
Illumina NextSeq 500 (Homo sapiens) |
|
C GSE124856
|
Chip-seq |
8 |
Illumina NextSeq 500 (Homo sapiens) |
|
C GSE230758
|
Chip-seq |
20 |
Illumina HiSeq 2500 (Homo sapiens) |
|
C GSE69877
|
Chip-seq |
10 |
Illumina HiSeq 2000 (Homo sapiens);Illumina NextSeq 500 (Homo sapiens) |
When the gene can detect a peak in the dataset, a peak plot will be displayed.
> Dataset: GSE147406 - CAMK2A peak across samples
|
Peak Plot
|
> Dataset: GSE124856 - CAMK2A peak across samples
|
Peak Plot
|
> Dataset: GSE230758 - CAMK2A peak across samples
|
Peak Plot
|
> Dataset: GSE69877 - CAMK2A peak across samples
|
Peak Plot
|
|
|
MCV Target gene Detail Information
