Gene Information
|
Gene Name
|
CD81 |
|
Gene ID
|
975
|
|
Gene Full Name
|
CD81 molecule |
|
Gene Alias
|
CVID6|S5.7|TAPA1|TSPAN28 |
|
Transcripts
|
ENSG00000110651
|
|
Virus
|
HCV |
|
Gene Type
|
protein-coding |
|
HPA Location Info
|
Plasma membrane;Cytosol; 
|
|
Membrane Info
|
CD markers, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters |
|
Uniport_ID
|
P60033
|
|
HGNC ID
|
HGNC:1701
|
|
OMIM ID
|
186845 |
|
Summary
|
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins. This protein appears to promote muscle cell fusion and support myotube maintenance. Also it may be involved in signal transduction. This gene is localized in the tumor-suppressor gene region and thus it is a candidate gene for malignancies. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014] |
Target gene [CD81] related to virus gene/protein/region 
Mutation Table: if previous studies reported that target gene was related to virus gene/region/protein, the information in this literature was listed in this section
Target gene [CD81] related to Omics data
| Data ID |
Experiment type |
Sample number |
Platform |
|
TCGA_LIHC_HCV
|
DNA methylation sequencing;RNA-seq |
97 |
TCGA |
|
GSE126831
|
RNA-seq |
63 |
Illumina NextSeq 500 (Homo sapiens) |
|
GSE212871
|
RNA-seq |
128 |
Illumina NovaSeq 6000 (Homo sapiens) |
|
GSE103730
|
Chip-seq;RNA-seq |
42 |
Illumina HiSeq 2500 (Homo sapiens) |
|
C GSE103728
|
Chip-seq |
24 |
Illumina HiSeq 2500 (Homo sapiens) |
|
GSE67848
|
RNA-seq |
12 |
Illumina HiSeq 2500 (Homo sapiens) |
|
GSE211161
|
RNA-seq |
4 |
Illumina HiSeq 2500 (Homo sapiens) |
When the gene can detect a peak in the dataset, a peak plot will be displayed.
> Dataset: GSE103728 - CD81 peak across samples
|
Peak Plot
|
|
|
HCV Target gene Detail Information
