Gene Name	CDH12
Gene ID	1010
Gene Full Name	cadherin 12
Gene Alias	CDHB
Transcripts	ENSG00000154162
Virus	HTLV1
Gene Type	protein-coding
HPA Location Info	Vesicles;
Membrane Info	Plasma proteins, Predicted membrane proteins
Uniport_ID	P55289
HGNC ID	HGNC:1751
OMIM ID	600562
Summary	This gene encodes a type II classical cadherin of the cadherin superfamily. Alternative splicing of this gene results in multiple transcript variants. At least one of these variants encodes a preproprotein that is proteolytically processed to generate the mature cadherin protein. These integral membrane proteins mediate calcium-dependent cell-cell adhesion and are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. Type II (atypical) cadherins are defined based on their lack of a histidine-alanine-valine (HAV) cell adhesion recognition sequence specific to type I cadherins. This particular cadherin appears to be expressed specifically in the brain and its temporal pattern of expression would be consistent with a role during a critical period of neuronal development, perhaps specifically during synaptogenesis. [provided by RefSeq, Nov 2015]

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
6006613	chr5	1	51	13	65	View
6016485	chr5	10	2	0	12	View
6016548	chr5	9	2	1	12	View
6017037	chr5	0	0	11	11	View
6027834	chr5	1	0	0	1	View
6029335	chr5	1	0	0	1	View
6030030	chr5	1	0	0	1	View
6030278	chr5	0	1	0	1	View
6031991	chr5	0	0	0	0	View
6032219	chr5	0	0	0	0	View

Data ID	Experiment type	Sample number	Platform
C   GSE94732	Chip-seq	24	Illumina NextSeq 500 (Homo sapiens);illumina Genome Analyzer IIx (Homo sapiens)
GSE168557	Expression array	6	Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Feature Number version)
GSE52244	Expression array	15	[HuEx-1_0-st] Affymetrix Human Exon 1.0 ST Array [probe set (exon) version]
GSE10789	Expression array	6	NCI/ATC Hs-OperonV3
GSE189602	Methylation profiling (Array)	4	Infinium MethylationEPIC
GSE136189	Methylation profiling (Array)	40	Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482);Illumina Infinium HumanMethylation850 BeadChip

• Genome binding/occupancy profiling

When the gene can detect a peak in the dataset, a peak plot will be displayed.

> Dataset: GSE94732 - CDH12 peak across samples

Peak Plot