Gene Information
|
Gene Name
|
CDK5RAP2 |
|
Gene ID
|
55755
|
|
Gene Full Name
|
CDK5 regulatory subunit associated protein 2 |
|
Gene Alias
|
C48|Cep215|MCPH3 |
|
Transcripts
|
ENSG00000136861
|
|
Virus
|
HTLV1 |
|
Gene Type
|
protein-coding |
|
HPA Location Info
|
Centrosome, Basal body;Cell Junctions, Cytosol, Equatorial segment, Mid piece, Principal piece; 
|
|
Membrane Info
|
Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins |
|
Uniport_ID
|
Q96SN8
|
|
HGNC ID
|
HGNC:18672
|
|
OMIM ID
|
608201 |
|
Summary
|
This gene encodes a regulator of CDK5 (cyclin-dependent kinase 5) activity. The protein encoded by this gene is localized to the centrosome and Golgi complex, interacts with CDK5R1 and pericentrin (PCNT), plays a role in centriole engagement and microtubule nucleation, and has been linked to primary microcephaly and Alzheimer's disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013] |
Target gene [CDK5RAP2] related to VISs 
Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section
| DVID |
Chromosome |
HM |
TFBS |
CA |
Sum of Overlapped Records |
Detail |
| 6003203 |
chr9 |
34 |
103 |
39 |
176 |
View |
| 6007693 |
chr9 |
9 |
34 |
9 |
52 |
View |
| 6020809 |
chr9 |
6 |
0 |
0 |
6 |
View |
| 6024019 |
chr9 |
1 |
3 |
0 |
4 |
View |
Target gene [CDK5RAP2] related to Omics data
| Data ID |
Experiment type |
Sample number |
Platform |
|
GSE189602
|
Methylation profiling (Array) |
4 |
Infinium MethylationEPIC |
|
C GSE94732
|
Chip-seq |
24 |
Illumina NextSeq 500 (Homo sapiens);illumina Genome Analyzer IIx (Homo sapiens) |
|
GSE52244
|
Expression array |
15 |
[HuEx-1_0-st] Affymetrix Human Exon 1.0 ST Array [probe set (exon) version] |
|
GSE10789
|
Expression array |
6 |
NCI/ATC Hs-OperonV3 |
|
GSE224047
|
RNA-seq |
10 |
Illumina NextSeq 500 (Homo sapiens) |
|
GSE168557
|
Expression array |
6 |
Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Feature Number version) |
|
GSE136189
|
Methylation profiling (Array) |
40 |
Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482);Illumina Infinium HumanMethylation850 BeadChip |
When the gene can detect a peak in the dataset, a peak plot will be displayed.
> Dataset: GSE94732 - CDK5RAP2 peak across samples
|
Peak Plot
|
|
|
HTLV1 Target gene Detail Information
