HPV Target gene Detail Information

> CEMIP2 Gene Search Result


Gene Information
Gene Name CEMIP2
Gene ID 23670
Gene Full Name cell migration inducing hyaluronidase 2
Gene Alias TMEM2
Transcripts ENSG00000135048
Virus HPV
Gene Type protein-coding
HPA Location Info Plasma membrane;Vesicles, Cytosol;
Membrane Info Enzymes, Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID Q9UHN6
HGNC ID HGNC:11869
OMIM ID 605835
Summary This gene encodes a type II transmembrane protein that belongs to the interferon-induced transmembrane (IFITM) protein superfamily. The encoded protein functions as a cell surface hyaluronidase that cleaves extracellular high molecular weight hyaluronan into intermediate size fragments before internalization and degradation in the lysosome. It also has an interferon-mediated antiviral function in humans through activation of the JAK STAT signaling pathway. The activation of this gene by transcription factor SOX4 in breast cancer cells has been shown to mediate the pathological effects of SOX4 on cancer progression. Naturally occurring mutations in this gene are associated with autosomal recessive non-syndromic hearing loss. [provided by RefSeq, Mar 2017]
Target gene [CEMIP2] related to VISs

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section


DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
5005532 chr9 5 3 0 8 View

Target gene [CEMIP2] related to Omics data
Data ID Experiment type Sample number Platform
C
  GSE183048 		Chip-seq 24 Illumina HiSeq 4000 (Homo sapiens)
GSE181805 Expression array 25 [HTA-2_0] Affymetrix Human Transcriptome Array 2.0 [transcript (gene) version]
GSE164690 scRNA-seq 51 Illumina NextSeq 500 (Homo sapiens)
GSE197461 scRNA-seq 16 Illumina NovaSeq 6000 (Homo sapiens)
GSE140662 Expression array 8 [HTA-2_0] Affymetrix Human Transcriptome Array 2.0 [transcript (gene) version]
TCGA_CESC DNA methylation sequencing;RNA-seq 288 TCGA
C
  GSE143026 		ATAC-seq;Chip-seq;RNA-seq 30 Illumina HiSeq 2500 (Homo sapiens)


When the gene can detect a peak in the dataset, a peak plot will be displayed.


> Dataset: GSE183048 - CEMIP2 peak across samples

Peak Plot

> Dataset: GSE143026 - CEMIP2 peak across samples

Peak Plot