HTLV1 Target gene Detail Information

> CNKSR2 Gene Search Result


Gene Information
Gene Name CNKSR2
Gene ID 22866
Gene Full Name connector enhancer of kinase suppressor of Ras 2
Gene Alias CNK2|KSR2|MAGUIN|MRXSHG
Transcripts ENSG00000149970
Virus HTLV1
Gene Type protein-coding
HPA Location Info Golgi apparatus, Plasma membrane;
Membrane Info Disease related genes, Human disease related genes, Predicted intracellular proteins
Uniport_ID Q8WXI2
HGNC ID HGNC:19701
OMIM ID 300724
Summary This gene encodes a multidomain protein that functions as a scaffold protein to mediate the mitogen-activated protein kinase pathways downstream from Ras. This gene product is induced by vitamin D and inhibits apoptosis in certain cancer cells. It may also play a role in ternary complex assembly of synaptic proteins at the postsynaptic membrane and coupling of signal transduction to membrane/cytoskeletal remodeling. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2009]
Target gene [CNKSR2] related to VISs

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section


DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
6003648 chrX 16 6 126 148 View
6029645 chrX 0 1 0 1 View

Target gene [CNKSR2] related to Omics data
Data ID Experiment type Sample number Platform
GSE189602 Methylation profiling (Array) 4 Infinium MethylationEPIC
C
  GSE94732 		Chip-seq 24 Illumina NextSeq 500 (Homo sapiens);illumina Genome Analyzer IIx (Homo sapiens)
GSE52244 Expression array 15 [HuEx-1_0-st] Affymetrix Human Exon 1.0 ST Array [probe set (exon) version]
GSE10789 Expression array 6 NCI/ATC Hs-OperonV3
GSE224047 RNA-seq 10 Illumina NextSeq 500 (Homo sapiens)
GSE168557 Expression array 6 Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Feature Number version)
GSE136189 Methylation profiling (Array) 40 Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482);Illumina Infinium HumanMethylation850 BeadChip


When the gene can detect a peak in the dataset, a peak plot will be displayed.


> Dataset: GSE94732 - CNKSR2 peak across samples

Peak Plot