Gene Name	COL22A1
Gene ID	169044
Gene Full Name	collagen type XXII alpha 1 chain
Gene Alias	-
Transcripts	ENSG00000169436
Virus	HTLV1
Gene Type	protein-coding
HPA Location Info	Vesicles;Endoplasmic reticulum;Secreted to extracellular matrix;
Membrane Info	Predicted intracellular proteins, Predicted secreted proteins
Uniport_ID	Q8NFW1
HGNC ID	HGNC:22989
OMIM ID	610026
Summary	This gene encodes member of the collagen family which is thought to contribute to the stabilization of myotendinous junctions and strengthen skeletal muscle attachments during contractile activity. It belongs to the fibril-associated collagens with interrupted triple helix (FACIT) subset of the collagen superfamily, which associate with collagen fibers through their C-terminal collagenous domains and mediate protein-protein interactions through their N-terminal noncollagenous domains. The encoded protein is deposited in the basement membrane zone of the myotendinous junction which is present only at the tissue junctions of muscles, tendons, the heart, articular cartilage, and skin. A knockdown of the orthologous zebrafish gene induces a muscular dystrophy by disruption of the myotendinous junction. [provided by RefSeq, May 2017]

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
6007966	chr8	18	32	0	50	View
6011975	chr8	18	6	0	24	View
6013821	chr8	18	0	0	18	View
6019366	chr8	8	0	0	8	View
6025667	chr8	3	0	0	3	View
6026546	chr8	1	1	0	2	View

Data ID	Experiment type	Sample number	Platform
C   GSE94732	Chip-seq	24	Illumina NextSeq 500 (Homo sapiens);illumina Genome Analyzer IIx (Homo sapiens)
GSE168557	Expression array	6	Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Feature Number version)
GSE52244	Expression array	15	[HuEx-1_0-st] Affymetrix Human Exon 1.0 ST Array [probe set (exon) version]
GSE10789	Expression array	6	NCI/ATC Hs-OperonV3
GSE189602	Methylation profiling (Array)	4	Infinium MethylationEPIC
GSE136189	Methylation profiling (Array)	40	Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482);Illumina Infinium HumanMethylation850 BeadChip

• Genome binding/occupancy profiling

When the gene can detect a peak in the dataset, a peak plot will be displayed.

> Dataset: GSE94732 - COL22A1 peak across samples

Peak Plot