Gene Information
|
Gene Name
|
CRHR2 |
|
Gene ID
|
1395
|
|
Gene Full Name
|
corticotropin releasing hormone receptor 2 |
|
Gene Alias
|
CRF-RB|CRF2|CRFR2|HM-CRF |
|
Transcripts
|
ENSG00000106113
|
|
Virus
|
HTLV1 |
|
Gene Type
|
protein-coding |
|
HPA Location Info
|
Plasma membrane;Secreted - unknown location; 
|
|
Membrane Info
|
G-protein coupled receptors, Predicted membrane proteins, Predicted secreted proteins |
|
Uniport_ID
|
Q13324
|
|
HGNC ID
|
HGNC:2358
|
|
OMIM ID
|
602034 |
|
Summary
|
The protein encoded by this gene belongs to the G-protein coupled receptor 2 family, and the subfamily of corticotropin releasing hormone receptor. This receptor shows high affinity for corticotropin releasing hormone (CRH), and also binds CRH-related peptides such as urocortin. CRH is synthesized in the hypothalamus, and plays an important role in coordinating the endocrine, autonomic, and behavioral responses to stress and immune challenge. Studies in mice suggest that this receptor maybe involved in mediating cardiovascular homeostasis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq, Jan 2011] |
Target gene [CRHR2] related to VISs 
Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section
| DVID |
Chromosome |
HM |
TFBS |
CA |
Sum of Overlapped Records |
Detail |
| 6002474 |
chr7 |
35 |
20 |
184 |
239 |
View |
| 6022026 |
chr7 |
5 |
0 |
0 |
5 |
View |
Target gene [CRHR2] related to Omics data
| Data ID |
Experiment type |
Sample number |
Platform |
|
C GSE94732
|
Chip-seq |
24 |
Illumina NextSeq 500 (Homo sapiens);illumina Genome Analyzer IIx (Homo sapiens) |
|
GSE168557
|
Expression array |
6 |
Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Feature Number version) |
|
GSE52244
|
Expression array |
15 |
[HuEx-1_0-st] Affymetrix Human Exon 1.0 ST Array [probe set (exon) version] |
|
GSE10789
|
Expression array |
6 |
NCI/ATC Hs-OperonV3 |
|
GSE189602
|
Methylation profiling (Array) |
4 |
Infinium MethylationEPIC |
|
GSE136189
|
Methylation profiling (Array) |
40 |
Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482);Illumina Infinium HumanMethylation850 BeadChip |
When the gene can detect a peak in the dataset, a peak plot will be displayed.
> Dataset: GSE94732 - CRHR2 peak across samples
|
Peak Plot
|
|
|
HTLV1 Target gene Detail Information
