HTLV1 Target gene Detail Information

> CTNND2 Gene Search Result


Gene Information
Gene Name CTNND2
Gene ID 1501
Gene Full Name catenin delta 2
Gene Alias GT24|NPRAP
Transcripts ENSG00000169862
Virus HTLV1
Gene Type protein-coding
HPA Location Info Nucleoplasm, Cell Junctions;Cytosol;
Membrane Info Disease related genes, Human disease related genes, Predicted intracellular proteins
Uniport_ID Q9UQB3
HGNC ID HGNC:2516
OMIM ID 604275
Summary This gene encodes an adhesive junction associated protein of the armadillo/beta-catenin superfamily and is implicated in brain and eye development and cancer formation. The protein encoded by this gene promotes the disruption of E-cadherin based adherens junction to favor cell spreading upon stimulation by hepatocyte growth factor. This gene is overexpressed in prostate adenocarcinomas and is associated with decreased expression of tumor suppressor E-cadherin in this tissue. This gene resides in a region of the short arm of chromosome 5 that is deleted in Cri du Chat syndrome. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2013]
Target gene [CTNND2] related to VISs

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section


DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
6008105 chr5 19 27 2 48 View
6008458 chr5 30 15 0 45 View
6012233 chr5 22 1 0 23 View
6017537 chr5 10 0 0 10 View
6019867 chr5 0 0 7 7 View
6020319 chr5 2 5 0 7 View
6024510 chr5 3 0 0 3 View
6028651 chr5 0 1 0 1 View
6030159 chr5 1 0 0 1 View
6030651 chr5 0 0 0 0 View
6033150 chr5 0 0 0 0 View

Target gene [CTNND2] related to Omics data
Data ID Experiment type Sample number Platform
C
  GSE94732 		Chip-seq 24 Illumina NextSeq 500 (Homo sapiens);illumina Genome Analyzer IIx (Homo sapiens)
GSE168557 Expression array 6 Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Feature Number version)
GSE52244 Expression array 15 [HuEx-1_0-st] Affymetrix Human Exon 1.0 ST Array [probe set (exon) version]
GSE10789 Expression array 6 NCI/ATC Hs-OperonV3
GSE189602 Methylation profiling (Array) 4 Infinium MethylationEPIC
GSE136189 Methylation profiling (Array) 40 Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482);Illumina Infinium HumanMethylation850 BeadChip


When the gene can detect a peak in the dataset, a peak plot will be displayed.


> Dataset: GSE94732 - CTNND2 peak across samples

Peak Plot