HTLV1 Target gene Detail Information

> CYFIP1 Gene Search Result


Gene Information
Gene Name CYFIP1
Gene ID 23191
Gene Full Name cytoplasmic FMR1 interacting protein 1
Gene Alias P140SRA-1|SHYC|SRA-1|SRA1
Transcripts ENSG00000273749
Virus HTLV1
Gene Type protein-coding
HPA Location Info
Membrane Info Predicted intracellular proteins
Uniport_ID Q7L576
HGNC ID HGNC:13759
OMIM ID 606322
Summary This gene encodes a protein that regulates cytoskeletal dynamics and protein translation. The encoded protein is a component of the WAVE regulatory complex (WRC), which promotes actin polymerization. This protein also interacts with the synaptic functional regulator FMR1 protein and translation initiation factor 4E to inhibit protein translation. A large chromosomal deletion including this gene is associated with increased risk of schizophrenia and epilepsy in human patients. Reduced expression of this gene has been observed in various human cancers and the encoded protein may inhibit tumor invasion. [provided by RefSeq, Mar 2022]
Target gene [CYFIP1] related to VISs

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section


DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
6003913 chr15 107 26 2 135 View
6004330 chr15 112 5 2 119 View
6009462 chr15 37 0 0 37 View
6011030 chr15 20 8 0 28 View

Target gene [CYFIP1] related to Omics data
Data ID Experiment type Sample number Platform
C
  GSE94732 		Chip-seq 24 Illumina NextSeq 500 (Homo sapiens);illumina Genome Analyzer IIx (Homo sapiens)
GSE168557 Expression array 6 Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Feature Number version)
GSE52244 Expression array 15 [HuEx-1_0-st] Affymetrix Human Exon 1.0 ST Array [probe set (exon) version]
GSE10789 Expression array 6 NCI/ATC Hs-OperonV3
GSE189602 Methylation profiling (Array) 4 Infinium MethylationEPIC
GSE136189 Methylation profiling (Array) 40 Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482);Illumina Infinium HumanMethylation850 BeadChip


When the gene can detect a peak in the dataset, a peak plot will be displayed.


> Dataset: GSE94732 - CYFIP1 peak across samples

Peak Plot