Gene Name	DENND4C
Gene ID	55667
Gene Full Name	DENN domain containing 4C
Gene Alias	C9orf55|C9orf55B|RAB10GEF|bA513M16.3
Transcripts	ENSG00000137145
Virus	HTLV1
Gene Type	protein-coding
HPA Location Info	Golgi apparatus, Vesicles, Cytosol;
Membrane Info	Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID	Q5VZ89
HGNC ID	HGNC:26079
Summary	Enables guanyl-nucleotide exchange factor activity. Predicted to be involved in cellular response to insulin stimulus; protein localization to plasma membrane; and regulation of Rab protein signal transduction. Located in Golgi apparatus and cytosol. [provided by Alliance of Genome Resources, Apr 2025]

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
6011750	chr9	24	1	0	25	View
6014386	chr9	16	0	0	16	View
6014391	chr9	16	0	0	16	View
6016603	chr9	11	1	0	12	View
6031095	chr9	0	0	0	0	View
6031346	chr9	0	0	0	0	View

Data ID	Experiment type	Sample number	Platform
GSE189602	Methylation profiling (Array)	4	Infinium MethylationEPIC
C   GSE94732	Chip-seq	24	Illumina NextSeq 500 (Homo sapiens);illumina Genome Analyzer IIx (Homo sapiens)
GSE52244	Expression array	15	[HuEx-1_0-st] Affymetrix Human Exon 1.0 ST Array [probe set (exon) version]
GSE10789	Expression array	6	NCI/ATC Hs-OperonV3
GSE224047	RNA-seq	10	Illumina NextSeq 500 (Homo sapiens)
GSE168557	Expression array	6	Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Feature Number version)
GSE136189	Methylation profiling (Array)	40	Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482);Illumina Infinium HumanMethylation850 BeadChip

• Genome binding/occupancy profiling

When the gene can detect a peak in the dataset, a peak plot will be displayed.

> Dataset: GSE94732 - DENND4C peak across samples

Peak Plot