HTLV1 Target gene Detail Information

> DGKB Gene Search Result


Gene Information
Gene Name DGKB
Gene ID 1607
Gene Full Name diacylglycerol kinase beta
Gene Alias DAGK2|DGK|DGK-BETA
Transcripts ENSG00000136267
Virus HTLV1
Gene Type protein-coding
HPA Location Info Plasma membrane;Nucleoplasm, Nuclear speckles;
Membrane Info Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins
Uniport_ID Q9Y6T7
HGNC ID HGNC:2850
OMIM ID 604070
Summary Diacylglycerol kinases (DGKs) are regulators of the intracellular concentration of the second messenger diacylglycerol (DAG) and thus play a key role in cellular processes. Nine mammalian isotypes have been identified, which are encoded by separate genes. Mammalian DGK isozymes contain a conserved catalytic (kinase) domain and a cysteine-rich domain (CRD). The protein encoded by this gene is a diacylglycerol kinase, beta isotype. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2017]
Target gene [DGKB] related to VISs

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section


DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
6023874 chr7 2 2 0 4 View
6029356 chr7 0 1 0 1 View

Target gene [DGKB] related to Omics data
Data ID Experiment type Sample number Platform
C
  GSE94732 		Chip-seq 24 Illumina NextSeq 500 (Homo sapiens);illumina Genome Analyzer IIx (Homo sapiens)
GSE168557 Expression array 6 Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Feature Number version)
GSE52244 Expression array 15 [HuEx-1_0-st] Affymetrix Human Exon 1.0 ST Array [probe set (exon) version]
GSE10789 Expression array 6 NCI/ATC Hs-OperonV3
GSE189602 Methylation profiling (Array) 4 Infinium MethylationEPIC
GSE136189 Methylation profiling (Array) 40 Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482);Illumina Infinium HumanMethylation850 BeadChip


When the gene can detect a peak in the dataset, a peak plot will be displayed.


> Dataset: GSE94732 - DGKB peak across samples

Peak Plot