Gene Information
|
Gene Name
|
DMRT2 |
|
Gene ID
|
10655
|
|
Gene Full Name
|
doublesex and mab-3 related transcription factor 2 |
|
Gene Alias
|
DSXL-2 |
|
Transcripts
|
ENSG00000173253
|
|
Virus
|
HTLV1 |
|
Gene Type
|
protein-coding |
|
HPA Location Info
|
Nucleoplasm, Nucleoli;Vesicles, Centriolar satellite; 
|
|
Membrane Info
|
Predicted intracellular proteins, Predicted membrane proteins, Transcription factors |
|
Uniport_ID
|
Q9Y5R5
|
|
HGNC ID
|
HGNC:2935
|
|
OMIM ID
|
604935 |
|
Summary
|
The protein encoded by this gene belongs to the DMRT gene family, sharing a DM DNA-binding domain with Drosophila 'doublesex' (dsx) and C. elegans mab3, genes involved in sex determination in these organisms. Also, this gene is located in a region of the human genome (chromosome 9p24.3) associated with gonadal dysgenesis and XY sex reversal. Hence this gene is one of the candidates for sex-determining gene(s) on chr 9. [provided by RefSeq, Apr 2010] |
Target gene [DMRT2] related to VISs 
Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section
| DVID |
Chromosome |
HM |
TFBS |
CA |
Sum of Overlapped Records |
Detail |
| 6013971 |
chr9 |
11 |
6 |
1 |
18 |
View |
| 6023229 |
chr9 |
1 |
0 |
3 |
4 |
View |
Target gene [DMRT2] related to Omics data
| Data ID |
Experiment type |
Sample number |
Platform |
|
C GSE94732
|
Chip-seq |
24 |
Illumina NextSeq 500 (Homo sapiens);illumina Genome Analyzer IIx (Homo sapiens) |
|
GSE168557
|
Expression array |
6 |
Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Feature Number version) |
|
GSE52244
|
Expression array |
15 |
[HuEx-1_0-st] Affymetrix Human Exon 1.0 ST Array [probe set (exon) version] |
|
GSE10789
|
Expression array |
6 |
NCI/ATC Hs-OperonV3 |
|
GSE189602
|
Methylation profiling (Array) |
4 |
Infinium MethylationEPIC |
|
GSE136189
|
Methylation profiling (Array) |
40 |
Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482);Illumina Infinium HumanMethylation850 BeadChip |
When the gene can detect a peak in the dataset, a peak plot will be displayed.
> Dataset: GSE94732 - DMRT2 peak across samples
|
Peak Plot
|
|
|
HTLV1 Target gene Detail Information
