HTLV1 Target gene Detail Information

> DOCK8 Gene Search Result


Gene Information
Gene Name DOCK8
Gene ID 81704
Gene Full Name dedicator of cytokinesis 8
Gene Alias HEL-205|HIES2|MRD2|ZIR8
Transcripts ENSG00000107099
Virus HTLV1
Gene Type protein-coding
HPA Location Info Plasma membrane, Cytosol;
Membrane Info Disease related genes, Human disease related genes, Predicted intracellular proteins
Uniport_ID Q8NF50
HGNC ID HGNC:19191
OMIM ID 611432
Summary This gene encodes a member of the DOCK180 family of guanine nucleotide exchange factors. Guanine nucleotide exchange factors interact with Rho GTPases and are components of intracellular signaling networks. Mutations in this gene result in the autosomal recessive form of the hyper-IgE syndrome. Alternatively spliced transcript variants encoding different isoforms have been described.[provided by RefSeq, Jun 2010]
Target gene [DOCK8] related to VISs

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section


DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
6007246 chr9 46 12 0 58 View
6007321 chr9 45 12 0 57 View
6009259 chr9 9 26 3 38 View
6016405 chr9 12 0 0 12 View
6019219 chr9 6 2 0 8 View

Target gene [DOCK8] related to Omics data
Data ID Experiment type Sample number Platform
GSE189602 Methylation profiling (Array) 4 Infinium MethylationEPIC
C
  GSE94732 		Chip-seq 24 Illumina NextSeq 500 (Homo sapiens);illumina Genome Analyzer IIx (Homo sapiens)
GSE52244 Expression array 15 [HuEx-1_0-st] Affymetrix Human Exon 1.0 ST Array [probe set (exon) version]
GSE10789 Expression array 6 NCI/ATC Hs-OperonV3
GSE224047 RNA-seq 10 Illumina NextSeq 500 (Homo sapiens)
GSE168557 Expression array 6 Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Feature Number version)
GSE136189 Methylation profiling (Array) 40 Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482);Illumina Infinium HumanMethylation850 BeadChip


When the gene can detect a peak in the dataset, a peak plot will be displayed.


> Dataset: GSE94732 - DOCK8 peak across samples

Peak Plot