Gene Name	DPP10
Gene ID	57628
Gene Full Name	dipeptidyl peptidase like 10
Gene Alias	DPL2|DPPY|DPRP-3|DPRP3
Transcripts	ENSG00000175497
Virus	HTLV1
Gene Type	protein-coding
HPA Location Info
Membrane Info	Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters
Uniport_ID	Q8N608
HGNC ID	HGNC:20823
OMIM ID	608209
Summary	This gene encodes a single-pass type II membrane protein that is a member of the S9B family in clan SC of the serine proteases. This protein has no detectable protease activity, most likely due to the absence of the conserved serine residue normally present in the catalytic domain of serine proteases. However, it does bind specific voltage-gated potassium channels and alters their expression and biophysical properties. Mutations in this gene have been associated with asthma. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
6005544	chr2	35	47	3	85	View
6010914	chr2	21	4	3	28	View
6012377	chr2	14	5	4	23	View
6014145	chr2	7	9	1	17	View
6015852	chr2	7	6	0	13	View
6016218	chr2	6	6	0	12	View
6016592	chr2	8	4	0	12	View
6019825	chr2	1	6	0	7	View
6020031	chr2	7	0	0	7	View
6020767	chr2	1	4	1	6	View
6024909	chr2	1	2	0	3	View
6027823	chr2	1	0	0	1	View
6028528	chr2	1	0	0	1	View
6028641	chr2	0	1	0	1	View
6031002	chr2	0	0	0	0	View
6031355	chr2	0	0	0	0	View
6032143	chr2	0	0	0	0	View

Data ID	Experiment type	Sample number	Platform
C   GSE94732	Chip-seq	24	Illumina NextSeq 500 (Homo sapiens);illumina Genome Analyzer IIx (Homo sapiens)
GSE168557	Expression array	6	Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Feature Number version)
GSE52244	Expression array	15	[HuEx-1_0-st] Affymetrix Human Exon 1.0 ST Array [probe set (exon) version]
GSE10789	Expression array	6	NCI/ATC Hs-OperonV3
GSE189602	Methylation profiling (Array)	4	Infinium MethylationEPIC
GSE136189	Methylation profiling (Array)	40	Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482);Illumina Infinium HumanMethylation850 BeadChip

• Genome binding/occupancy profiling

When the gene can detect a peak in the dataset, a peak plot will be displayed.

> Dataset: GSE94732 - DPP10 peak across samples

Peak Plot