Gene Information
|
Gene Name
|
DPP6 |
|
Gene ID
|
1804
|
|
Gene Full Name
|
dipeptidyl peptidase like 6 |
|
Gene Alias
|
DPL1|DPPX|MRD33|VF2 |
|
Transcripts
|
ENSG00000130226
|
|
Virus
|
HTLV1 |
|
Gene Type
|
protein-coding |
|
HPA Location Info
|
|
|
Membrane Info
|
Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters |
|
Uniport_ID
|
P42658
|
|
HGNC ID
|
HGNC:3010
|
|
OMIM ID
|
126141 |
|
Summary
|
This gene encodes a single-pass type II membrane protein that is a member of the peptidase S9B family of serine proteases. This protein has no detectable protease activity, most likely due to the absence of the conserved serine residue normally present in the catalytic domain of serine proteases. However, it does bind specific voltage-gated potassium channels and alters their expression and biophysical properties. Variations in this gene may be associated with susceptibility to amyotrophic lateral sclerosis and with idiopathic ventricular fibrillation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014] |
Target gene [DPP6] related to VISs 
Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section
| DVID |
Chromosome |
HM |
TFBS |
CA |
Sum of Overlapped Records |
Detail |
| 6002203 |
chr7 |
7 |
203 |
61 |
271 |
View |
| 6007303 |
chr7 |
47 |
8 |
2 |
57 |
View |
| 6008170 |
chr7 |
34 |
3 |
11 |
48 |
View |
| 6023653 |
chr7 |
4 |
0 |
0 |
4 |
View |
| 6030563 |
chr7 |
0 |
0 |
0 |
0 |
View |
| 6031432 |
chr7 |
0 |
0 |
0 |
0 |
View |
| 6031608 |
chr7 |
0 |
0 |
0 |
0 |
View |
Target gene [DPP6] related to Omics data
| Data ID |
Experiment type |
Sample number |
Platform |
|
C GSE94732
|
Chip-seq |
24 |
Illumina NextSeq 500 (Homo sapiens);illumina Genome Analyzer IIx (Homo sapiens) |
|
GSE168557
|
Expression array |
6 |
Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Feature Number version) |
|
GSE52244
|
Expression array |
15 |
[HuEx-1_0-st] Affymetrix Human Exon 1.0 ST Array [probe set (exon) version] |
|
GSE10789
|
Expression array |
6 |
NCI/ATC Hs-OperonV3 |
|
GSE189602
|
Methylation profiling (Array) |
4 |
Infinium MethylationEPIC |
|
GSE136189
|
Methylation profiling (Array) |
40 |
Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482);Illumina Infinium HumanMethylation850 BeadChip |
When the gene can detect a peak in the dataset, a peak plot will be displayed.
> Dataset: GSE94732 - DPP6 peak across samples
|
Peak Plot
|
|
|
HTLV1 Target gene Detail Information
