Gene Information
|
Gene Name
|
DSG2 |
|
Gene ID
|
1829
|
|
Gene Full Name
|
desmoglein 2 |
|
Gene Alias
|
CDHF5|HDGC |
|
Transcripts
|
ENSG00000046604
|
|
Virus
|
HTLV1 |
|
Gene Type
|
protein-coding |
|
HPA Location Info
|
Cell Junctions; 
|
|
Membrane Info
|
Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins |
|
Uniport_ID
|
Q14126
|
|
HGNC ID
|
HGNC:3049
|
|
OMIM ID
|
125671 |
|
Summary
|
This gene encodes a member of the desmoglein family and cadherin cell adhesion molecule superfamily of proteins. Desmogleins are calcium-binding transmembrane glycoprotein components of desmosomes, cell-cell junctions between epithelial, myocardial, and other cell types. The encoded preproprotein is proteolytically processed to generate the mature glycoprotein. This gene is present in a gene cluster with other desmoglein gene family members on chromosome 18. Mutations in this gene have been associated with arrhythmogenic right ventricular dysplasia, familial, 10. [provided by RefSeq, Jan 2016] |
Target gene [DSG2] related to VISs 
Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section
| DVID |
Chromosome |
HM |
TFBS |
CA |
Sum of Overlapped Records |
Detail |
| 6013980 |
chr18 |
15 |
2 |
0 |
17 |
View |
| 6013982 |
chr18 |
15 |
2 |
0 |
17 |
View |
| 6013984 |
chr18 |
15 |
2 |
0 |
17 |
View |
| 6013987 |
chr18 |
15 |
2 |
0 |
17 |
View |
| 6013993 |
chr18 |
15 |
2 |
0 |
17 |
View |
| 6014003 |
chr18 |
15 |
2 |
0 |
17 |
View |
| 6014006 |
chr18 |
15 |
2 |
0 |
17 |
View |
Target gene [DSG2] related to Omics data
| Data ID |
Experiment type |
Sample number |
Platform |
|
C GSE94732
|
Chip-seq |
24 |
Illumina NextSeq 500 (Homo sapiens);illumina Genome Analyzer IIx (Homo sapiens) |
|
GSE168557
|
Expression array |
6 |
Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Feature Number version) |
|
GSE52244
|
Expression array |
15 |
[HuEx-1_0-st] Affymetrix Human Exon 1.0 ST Array [probe set (exon) version] |
|
GSE10789
|
Expression array |
6 |
NCI/ATC Hs-OperonV3 |
|
GSE189602
|
Methylation profiling (Array) |
4 |
Infinium MethylationEPIC |
|
GSE136189
|
Methylation profiling (Array) |
40 |
Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482);Illumina Infinium HumanMethylation850 BeadChip |
When the gene can detect a peak in the dataset, a peak plot will be displayed.
> Dataset: GSE94732 - DSG2 peak across samples
|
Peak Plot
|
|
|
HTLV1 Target gene Detail Information
