HTLV1 Target gene Detail Information

> EGLN3 Gene Search Result


Gene Information
Gene Name EGLN3
Gene ID 112399
Gene Full Name egl-9 family hypoxia inducible factor 3
Gene Alias HIFP4H3|HIFPH3|PHD3
Transcripts ENSG00000129521
Virus HTLV1
Gene Type protein-coding
HPA Location Info Cytosol;
Membrane Info Enzymes, FDA approved drug targets, Predicted intracellular proteins
Uniport_ID Q9H6Z9
HGNC ID HGNC:14661
OMIM ID 606426
Summary Enables peptidyl-proline 4-dioxygenase activity. Involved in several processes, including positive regulation of cysteine-type endopeptidase activity; protein hydroxylation; and response to hypoxia. Located in cytosol and nucleus. Implicated in renal cell carcinoma. Biomarker of clear cell renal cell carcinoma. [provided by Alliance of Genome Resources, Apr 2025]
Target gene [EGLN3] related to VISs

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section


DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
6006294 chr14 15 30 26 71 View

Target gene [EGLN3] related to Omics data
Data ID Experiment type Sample number Platform
C
  GSE94732 		Chip-seq 24 Illumina NextSeq 500 (Homo sapiens);illumina Genome Analyzer IIx (Homo sapiens)
GSE168557 Expression array 6 Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Feature Number version)
GSE52244 Expression array 15 [HuEx-1_0-st] Affymetrix Human Exon 1.0 ST Array [probe set (exon) version]
GSE10789 Expression array 6 NCI/ATC Hs-OperonV3
GSE189602 Methylation profiling (Array) 4 Infinium MethylationEPIC
GSE136189 Methylation profiling (Array) 40 Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482);Illumina Infinium HumanMethylation850 BeadChip


When the gene can detect a peak in the dataset, a peak plot will be displayed.


> Dataset: GSE94732 - EGLN3 peak across samples

Peak Plot