HTLV1 Target gene Detail Information

> EIF4G3 Gene Search Result


Gene Information
Gene Name EIF4G3
Gene ID 8672
Gene Full Name eukaryotic translation initiation factor 4 gamma 3
Gene Alias eIF-4G 3|eIF4G 3|eIF4GII
Transcripts ENSG00000075151
Virus HTLV1
Gene Type protein-coding
HPA Location Info Cytosol;
Membrane Info Plasma proteins, Predicted intracellular proteins
Uniport_ID O43432
HGNC ID HGNC:3298
OMIM ID 603929
Summary The protein encoded by this gene is thought to be part of the eIF4F protein complex, which is involved in mRNA cap recognition and transport of mRNAs to the ribosome. Interestingly, a microRNA (miR-520c-3p) has been found that negatively regulates synthesis of the encoded protein, and this leads to a global decrease in protein translation and cell proliferation. Therefore, this protein is a key component of the anti-tumor activity of miR-520c-3p. [provided by RefSeq, May 2016]
Target gene [EIF4G3] related to VISs

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section


DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
6000329 chr1 1857 121 117 2095 View
6024682 chr1 2 1 0 3 View
6028684 chr1 1 0 0 1 View
6032136 chr1 0 0 0 0 View

Target gene [EIF4G3] related to Omics data
Data ID Experiment type Sample number Platform
GSE189602 Methylation profiling (Array) 4 Infinium MethylationEPIC
C
  GSE94732 		Chip-seq 24 Illumina NextSeq 500 (Homo sapiens);illumina Genome Analyzer IIx (Homo sapiens)
GSE52244 Expression array 15 [HuEx-1_0-st] Affymetrix Human Exon 1.0 ST Array [probe set (exon) version]
GSE10789 Expression array 6 NCI/ATC Hs-OperonV3
GSE224047 RNA-seq 10 Illumina NextSeq 500 (Homo sapiens)
GSE168557 Expression array 6 Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Feature Number version)
GSE136189 Methylation profiling (Array) 40 Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482);Illumina Infinium HumanMethylation850 BeadChip


When the gene can detect a peak in the dataset, a peak plot will be displayed.


> Dataset: GSE94732 - EIF4G3 peak across samples

Peak Plot