Gene Information
|
Gene Name
|
EML4 |
|
Gene ID
|
27436
|
|
Gene Full Name
|
EMAP like 4 |
|
Gene Alias
|
C2orf2|ELP120|EMAP-4|EMAPL4|ROPP120 |
|
Transcripts
|
ENSG00000143924
|
|
Virus
|
HTLV1 |
|
Gene Type
|
protein-coding |
|
HPA Location Info
|
Microtubules, Primary cilium, Annulus;Cytokinetic bridge, Cytosol, Perinuclear theca, Calyx, Principal piece; 
|
|
Membrane Info
|
Cancer-related genes, Disease related genes, Predicted intracellular proteins |
|
Uniport_ID
|
Q9HC35
|
|
HGNC ID
|
HGNC:1316
|
|
OMIM ID
|
607442 |
|
Summary
|
This gene is a member of the echinoderm microtubule associated protein-like family. The encoded WD-repeat protein may be involved in microtubule formation. Abnormal fusion of parts of this gene with portions of the anaplastic lymphoma receptor tyrosine kinase gene, which generates EML4-ALK fusion transcripts, is one of the primary mutations associated with non-small cell lung cancer. Alternative splicing of this gene results in two transcript variants. [provided by RefSeq, Jan 2015] |
Target gene [EML4] related to VISs 
Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section
| DVID |
Chromosome |
HM |
TFBS |
CA |
Sum of Overlapped Records |
Detail |
| 6019267 |
chr2 |
8 |
0 |
0 |
8 |
View |
Target gene [EML4] related to Omics data
| Data ID |
Experiment type |
Sample number |
Platform |
|
GSE189602
|
Methylation profiling (Array) |
4 |
Infinium MethylationEPIC |
|
C GSE94732
|
Chip-seq |
24 |
Illumina NextSeq 500 (Homo sapiens);illumina Genome Analyzer IIx (Homo sapiens) |
|
GSE52244
|
Expression array |
15 |
[HuEx-1_0-st] Affymetrix Human Exon 1.0 ST Array [probe set (exon) version] |
|
GSE10789
|
Expression array |
6 |
NCI/ATC Hs-OperonV3 |
|
GSE224047
|
RNA-seq |
10 |
Illumina NextSeq 500 (Homo sapiens) |
|
GSE168557
|
Expression array |
6 |
Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Feature Number version) |
|
GSE136189
|
Methylation profiling (Array) |
40 |
Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482);Illumina Infinium HumanMethylation850 BeadChip |
When the gene can detect a peak in the dataset, a peak plot will be displayed.
> Dataset: GSE94732 - EML4 peak across samples
|
Peak Plot
|
|
|
HTLV1 Target gene Detail Information
