Gene Information
|
Gene Name
|
EPHA3 |
|
Gene ID
|
2042
|
|
Gene Full Name
|
EPH receptor A3 |
|
Gene Alias
|
EK4|ETK|ETK1|HEK|HEK4|TYRO4 |
|
Transcripts
|
ENSG00000044524
|
|
Virus
|
HTLV1 |
|
Gene Type
|
protein-coding |
|
HPA Location Info
|
Nuclear membrane, Plasma membrane, Cytosol;Nucleoplasm, Actin filaments;Intracellular and membrane; 
|
|
Membrane Info
|
Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins |
|
Uniport_ID
|
P29320
|
|
HGNC ID
|
HGNC:3387
|
|
OMIM ID
|
179611 |
|
Summary
|
This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. This gene encodes a protein that binds ephrin-A ligands. Two alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Jul 2008] |
Target gene [EPHA3] related to VISs 
Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section
| DVID |
Chromosome |
HM |
TFBS |
CA |
Sum of Overlapped Records |
Detail |
| 6012819 |
chr3 |
12 |
3 |
6 |
21 |
View |
| 6012852 |
chr3 |
15 |
3 |
3 |
21 |
View |
| 6016425 |
chr3 |
1 |
11 |
0 |
12 |
View |
| 6018552 |
chr3 |
7 |
1 |
1 |
9 |
View |
| 6023253 |
chr3 |
2 |
2 |
0 |
4 |
View |
| 6025405 |
chr3 |
2 |
1 |
0 |
3 |
View |
| 6025815 |
chr3 |
1 |
2 |
0 |
3 |
View |
| 6025880 |
chr3 |
0 |
2 |
0 |
2 |
View |
| 6025895 |
chr3 |
0 |
2 |
0 |
2 |
View |
| 6030873 |
chr3 |
0 |
0 |
0 |
0 |
View |
| 6031232 |
chr3 |
0 |
0 |
0 |
0 |
View |
| 6031486 |
chr3 |
0 |
0 |
0 |
0 |
View |
Target gene [EPHA3] related to Omics data
| Data ID |
Experiment type |
Sample number |
Platform |
|
C GSE94732
|
Chip-seq |
24 |
Illumina NextSeq 500 (Homo sapiens);illumina Genome Analyzer IIx (Homo sapiens) |
|
GSE168557
|
Expression array |
6 |
Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Feature Number version) |
|
GSE52244
|
Expression array |
15 |
[HuEx-1_0-st] Affymetrix Human Exon 1.0 ST Array [probe set (exon) version] |
|
GSE10789
|
Expression array |
6 |
NCI/ATC Hs-OperonV3 |
|
GSE189602
|
Methylation profiling (Array) |
4 |
Infinium MethylationEPIC |
|
GSE136189
|
Methylation profiling (Array) |
40 |
Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482);Illumina Infinium HumanMethylation850 BeadChip |
When the gene can detect a peak in the dataset, a peak plot will be displayed.
> Dataset: GSE94732 - EPHA3 peak across samples
|
Peak Plot
|
|
|
HTLV1 Target gene Detail Information
