HTLV1 Target gene Detail Information

> FTO Gene Search Result


Gene Information
Gene Name FTO
Gene ID 79068
Gene Full Name FTO alpha-ketoglutarate dependent dioxygenase
Gene Alias ALKBH9|BMIQ14|GDFD|IFEX9
Transcripts ENSG00000140718
Virus HTLV1
Gene Type protein-coding
HPA Location Info Cytosol;Vesicles;
Membrane Info Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins
Uniport_ID Q9C0B1
HGNC ID HGNC:24678
OMIM ID 610966
Summary This gene is a nuclear protein of the AlkB related non-haem iron and 2-oxoglutarate-dependent oxygenase superfamily but the exact physiological function of this gene is not known. Other non-heme iron enzymes function to reverse alkylated DNA and RNA damage by oxidative demethylation. Studies in mice and humans indicate a role in nervous and cardiovascular systems and a strong association with body mass index, obesity risk, and type 2 diabetes. [provided by RefSeq, Jul 2011]
Target gene [FTO] related to VISs

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section


DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
6021300 chr16 6 0 0 6 View
6026898 chr16 1 1 0 2 View
6027057 chr16 2 0 0 2 View
6031376 chr16 0 0 0 0 View
6032913 chr16 0 0 0 0 View

Target gene [FTO] related to Omics data
Data ID Experiment type Sample number Platform
GSE189602 Methylation profiling (Array) 4 Infinium MethylationEPIC
C
  GSE94732 		Chip-seq 24 Illumina NextSeq 500 (Homo sapiens);illumina Genome Analyzer IIx (Homo sapiens)
GSE52244 Expression array 15 [HuEx-1_0-st] Affymetrix Human Exon 1.0 ST Array [probe set (exon) version]
GSE10789 Expression array 6 NCI/ATC Hs-OperonV3
GSE224047 RNA-seq 10 Illumina NextSeq 500 (Homo sapiens)
GSE168557 Expression array 6 Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Feature Number version)
GSE136189 Methylation profiling (Array) 40 Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482);Illumina Infinium HumanMethylation850 BeadChip


When the gene can detect a peak in the dataset, a peak plot will be displayed.


> Dataset: GSE94732 - FTO peak across samples

Peak Plot